podgaj

18 ms·

151.
by podgaj 5y ago
Maybe not missing ion channels, but it does seem to be caused by over sensitive ion channels, and several different ones. They used to think it was just sodium channels but now they find the calcium channels (which are also implicated in Bi
152.
by podgaj 5y ago
Then maybe we should change something more fundamental? Like maybe not have an economic system that depends on some false notion of social darwinism?
153.
by podgaj 5y ago
> Why should Uber (and, by extension both drivers and users) be forced to treat all users as if they are the most expensive users? It's about kindness. These companies want to treat ALL customers as the least expensive user. Don&#x2
154.
by podgaj 5y ago
I am done with the internet. It is nothing but toxic positivity.
155.
by podgaj 5y ago
>But we have a way of defining who is poor and who isn't in terms of income Yes, the definitions. Is it a definition or a lived experience? Politicians love to define away poverty. These definitions are how millionaires were able to
156.
by podgaj 5y ago
I guess getting downvoted on this means there is no chance of a third party....
157.
by podgaj 5y ago
Poor people, which is a large majority of the United States, can only afford processed food. You neoliberals in your whole foods crap make me nauseous.
158.
by podgaj 5y ago
But you’re mistaking inflation for the rate of inflation growth. The rate of inflation growth is horrible right now.
159.
by podgaj 5y ago
Democrats are the Charlie Brown’s of politics. And Republicans are Lucy.
160.
by podgaj 5y ago
I agree. Plus if you look at 90 day credit card delinquency’s and credit card balances they’re going in the opposite direction. Delinquency’s are going down right now, but inflation can change this quickly. It’s been said that the lower del
161.
by podgaj 5y ago
I live in disability. And I can tell you the inflation is serious.
162.
by podgaj 5y ago
People are still making money from the process whether I do it before or after the sale.
163.
by podgaj 5y ago
If there is no original than all digital artwork is worthless because it can be endlessly copied which would diminish its value. Rarity is what dictates price, not only social decisions. If I make an NFT of my photograph and sell it to some
164.
by podgaj 5y ago
>If that's what's happening, why are most of the Twitter-famous whale collectors completely anonymous? Because it is an easy way to launder/hide money?
165.
by podgaj 5y ago
NFTs, what a scam. I had no idea what the process was. I was a photographer in my younger days, published. Thought I could make a buck or two turning them into an NFT. NFTs are the people selling shovels during the gold rush, a for someone
166.
by podgaj 5y ago
As an example I will show how taking his dose riboflavin might increase the need for Zinc and Magnesium. To turn Riboflavin into FMN using an enzyme called RFK, which needs zinc and magnesium as cofactors: https://www.uniprot.org
167.
by podgaj 5y ago
It is not the usual doctor stuff, but it should be. I was misdiagnosed my whole life even though it was obvious there was some maternal genetic (metabolic/mood/immune) issues passed down through my family. It was only my own effor
168.
by podgaj 5y ago
It's genetic, and partial. Unless you know your genetics, telling someone what they need is useless. I know my genetics. And I tried Thiamine years ago. It made me manic, most likely because my real issue was a depletion of manganese t
169.
by podgaj 5y ago
garbanzos, would you mind contacting me at phaser.spa-0a@icloud.com (iCloud private relay) I think we have a lot we can collaborate on and talk about.
170.
by podgaj 5y ago
chiefalchemist, I do not understand your comment and it is probably a result of your misinterpretation of what I have proposed. I understand that my idea seems simple, but what I am proposing is that many people could have an inability to h
171.
by podgaj 5y ago
The only thread I can find that runs through all these disorders is an inability to balance oxidative stress. The reason symptomatic COVID will vary so much between people is that genetics, nutrition, and life stress are all variables that
172.
by podgaj 5y ago
As someone with a Complex I Deficiency I did not know you could "unblock" the electron transport chain. Taking these supplements without knowing your genetics will result in undue suffering and confusion. And to speak of the elect
173.
by podgaj 5y ago
As someone who is disabled with a mitochondrial disease (Complex 1 Deficiency) that expresses as a mood disorder (which includes the anxiety they speak of in the article) and ME/CFS, I feel sure enough to posit that the cause of all th
174.
by podgaj 5y ago
No, and it wold probably make things worse if this is true. Tryptophan is turned into NAD but if you do not have enough of the cofactors to make NAD down the Kynurenine pathway then you will just deplete yourself of cofactors even further.
175.
by podgaj 5y ago
The ONLY things that will stimulate SOD activity are superoxides. But the SOD enzymes need cofactors to work effectively. SOD1 and SOD3 (Extracellular) needs Copper and Zinc SOD2 (intracellular) needs Manganese (not magnesium) It is possibl
176.
by podgaj 5y ago
Sometime science is stupid. You see they thought that since there was an increase activity of SOD enzymes after drinking Green Tea that it meant the EGCG was stimulating the enzyme directly. What was in fact happening is that EGCG was creat
177.
Green tea catechins promote oxidative stress(bionity.com)
4 points by podgaj 5y ago|2 comments
178.
by podgaj 5y ago
It is not permanent, the SD goes away after about a month of stopping prozac. It has a long half life so it can seem like forever though.
179.
by podgaj 5y ago
The mechanism of action how this helps is probably so simple that people who have over complicated thoughts cannot see the answer. Serotonin is made from tryptophan by the TPH enzyme. But Tryprtophan is also turned into kynurenine by an enz
180.
by podgaj 5y ago
Don't count on it... https://www.1800petmeds.com/Fluoxetine-prod10489.html

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