The ONLY things that will stimulate SOD activity are superoxides. But the SOD enzymes need cofactors to work effectively. SOD1 and SOD3 (Extracellular) needs C

The ONLY things that will stimulate SOD activity are superoxides. But the SOD enzymes need cofactors to work effectively. SOD1 and SOD3 (Extracellular) needs Copper and Zinc SOD2 (intracellular) needs Manganese (not magnesium) It is possible that these cofactors will stimulate SOD on their own.