w10-1

48 ms·

571.
by w10-1 2y ago
Relatedly: I wish there was a practice of acknowledging when you give up. I've seen so many people just slink away from their PhD's, perhaps with a nominal masters, but always in some kind of defeat, without accepting or sorting o
572.
by w10-1 2y ago
Heraclitus plead, "Listen not to me but the logos (word)" i.e., to honor SJ, it may be best to pick up his work - to respect what he respected - instead of lining up in idolatry. In this case, the key insight about design is not t
573.
by w10-1 2y ago
There's another difficulty: to get the numbers needed to validate that a drug works, an equivalent large number of people need to enter the trial in the non-treatment arm, typically foregoing other treatment. Many people refuse to joi
574.
by w10-1 2y ago
It is the standard for all security domains - police, army, etc. I would reword it to say that security should work for the oblivious user, and we should not depend on good user behavior (or fail to defend against malicious or negligent beh
575.
by w10-1 2y ago
Virtually all diagrams are representations of declarations that are the source of truth. Visual editors just help you edit that, but rarely get close to validating the underlying structure. For things like programming languages and markdow
576.
by w10-1 2y ago
When something needed does not evolve, it helps to understand why, and address that. Yes, visualizing the expected programming model helps with programming. Tech leads should convey the programming model somehow, and graphics can help. Th
577.
by w10-1 2y ago
I think Swift is close to optimal for now. It does have the union type Result<normal, error>, but most people throw/catch Error. In Swift, error is a simple value (without a stack frame) and thus is as cheap as a return value, bu
578.
by w10-1 2y ago
Yes, pathways are complex and adaptive, but as I read the abstract (thank you!), they're suggesting a treatment path. The potential treatment is that the protein JUN can block IFN's increasing CXCL13 pathologically. It's test
579.
by w10-1 2y ago
Toyota practice had such impact because it empowered people to speak up. It's not clear this article is empowering in that sense. Instead of tracking/pleasing your boss, quality principles were stated and your job was to implement
580.
by w10-1 2y ago
> Obstinacy is defined by a lack of imagination, good judgement, and intent listening I think that may be a mistake. Any value strategy that is primarily conservative (e.g., protecting sunk or resource assets) will be obstinate. That do
581.
by w10-1 2y ago
Both persistence and obstinance are somewhat social. Many persistent leaders become obstinate when they develop a success history that surrounds them with positive feedback - yes-men, resources to waste, etc. Obstinate people flock together
582.
by w10-1 2y ago
The Quality perspective seems more like persistence to me, attacking every potential issue (like Howard Hughes polishing rivets). Persistence to me extends the reality principle to even minor and potential issues: they *must* be addressed (
583.
by w10-1 2y ago
> What do you think the mechanism behind this is Estrogen in the brain is neuro-protective and neuro-trophic. The primary source of estrogen in the brain for men is testosterone converted via aromatase. However, that's speculative.
584.
by w10-1 2y ago
I recall enterprising lawyers researched California coastal property titles back to the 19th century to overcome more recent prohibitions on subdivision -- successfully! Does anyone remember their names or details?
585.
by w10-1 2y ago
The essence, from the majority opinion https://www.supremecourt.gov/opinions/23pdf/23-939_e2pg.pdf > nature of Presidential power entitles a former President to absolute immunity from criminal prosecution
586.
by w10-1 2y ago
With VSC, the only extensions are those MS builds API's for. It's hub and spoke integration, for a few big leaders and many tiny followers. With Eclipse (Theia or otherwise), it's fully open, with a large number of medium-s
587.
by w10-1 2y ago
Java, because: Mark Reinhold He learned from the best.
588.
by w10-1 2y ago
Justice Kagan for the longest time has been the liberal that tried to reconcile with the rest of the court. But she delivered her dissent orally and framed it broadly, signaling that there is no possibility of reconciliation. That unfortuna
589.
by w10-1 2y ago
I'm curious (read "doubtful") about the claims for reliably detecting DNA and proteins in soils that are 100K+ years old. For medical diagnostics, we even had trouble with small samples of blood directly and reliably obtained
590.
by w10-1 2y ago
Aside from that excellent summary of features: the model of cards in stacks sending messages to components or up through a hierarchy was SmallTalk-inspired and enabled plain old people to do a kind of object-oriented programming long before
591.
by w10-1 2y ago
> Bill Atkinson went on an LSD trip and had the idea for HyperCard There's another (to me more plausible) story. Steve Jobs had plans for a 20MB hard drive, but marketing could not find users who wanted that much space. So Steve a
592.
by w10-1 2y ago
This is so promising! I presume like pandoc, the goal is to use an internal model to reduce the M*N complexity of format transcoding to M+N. But when I look at the tests for this (and Dasel and rq also mentioned here), I see very little. j
593.
by w10-1 2y ago
Approved with 40% experiencing liver injury? Check out the statistical evaluation sections on the study outcomes: https://www.fda.gov/vaccines-blood-biologics/tissue-tissue-products/elevidys I could see appr
594.
by w10-1 2y ago
> coming from folks who are really against open-source AI to begin with strike me as a bad faith debate tactic Meaning: really against AI? But Nietzsche said it's our enemies who are honest with us. > do not wish any more barrie
595.
by w10-1 2y ago
> You're not Google. Your company will never be Google True, but the CTO comes from twitter/meta/google/some open-source big-data project, the director loves databases, etc. So we have 40-100 people managing queues wi
596.
by w10-1 2y ago
A small caveat is that the idea of friction suggests resistance to a necessary change, and the concept drives one towards more flexibility and power. In my experience, it is simplification that reduces friction: accepting constraints and li
597.
by w10-1 2y ago
Complexity is just one of the many kinds of requirements. And yes, requirements (despite their name) can be somewhat fungible. And if you keep going, you'll think of yourself as a forcing function for humanizing humanity. For me the
598.
by w10-1 2y ago
Go co-routines are the same: a bit of magic you just use and don't think much about. I'd argue the primary magic in large-scale languages should mainly be in those two places: inversion of control and concurrency.
599.
by w10-1 2y ago
> you ever want cheaper Adobe subscriptions is to cancel your sub and they’ll send you repeat offers at lower prices up to 60% off That used to be true at NYTimes and WaPo. But new WaPo management does the reverse: - offer to keep
600.
by w10-1 2y ago
This is not oligopoly, but the result of technology as an enhancer delivering more value to the leader. E.g., in the 1990's vehicles for commercializing movies took off. Toys, fast-food tie-in's with well-timed ad campaigns and p

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