Yes, pathways are complex and adaptive, but as I read the abstract (thank you!), they're suggesting a treatment path. The potential treatment is that the prote

Yes, pathways are complex and adaptive, but as I read the abstract (thank you!), they're suggesting a treatment path. The potential treatment is that the protein JUN can block IFN's increasing CXCL13 pathologically. It's testable in that JUN itself can be produced and delivered during acute phases to reduce flares, and could itself be a therapy. More lasting gene diagnostics and therapies may come from checking for dysregulated genes in the pathway and injecting genes to produce JUN. It's not promising, though, to the extent JUN wouldn't address an underlying IFN dysregulation.