gww

9 ms·

61.
by gww 5y ago
If you haven't read it The Making of the Atomic Bomb by Richard Rhodes is in the same vein and excellent. It doesn't focus on a single physicist but covers a lot of the physics and chemistry that led to the construction of the ato
62.
by gww 5y ago
What made you decide to take notes on a paper rather than markup the pdf it's self? I have recently been reorganizing my citations as I transition to bring an independent investigator and I have been debating which method I prefer
63.
by gww 5y ago
One point that I seem rarely mentioned especially in the life sciences is learning when to tell your mentor that you have enough to leave. In my experience a lot of labs will try to keep their senior PhD students around as long as they can
64.
by gww 5y ago
This is a huge struggle for me as a computational biologist with a computer science background. When I use a published method I try to have at least a cursory understanding of how the method works. However, many of the papers in my field
65.
by gww 5y ago
It's very common to use 2 bits per nucleotide despite the human genome having ambiguous bases on top of the 4 letters. These tools typically encode the ambiguous base as a random nucleotide but keep track of them and then convert them
66.
by gww 5y ago
I am so glad I am not the only one who did this. I was messing around with the phone wires because my sister was hogging the phone and I had important business on a MUD. I found if I put a large resistor across two of the wires (I can&#x27
67.
by gww 5y ago
It's from the Who Shot Mr. Burns Episode (S06E25) [1]. [1] https://en.wikipedia.org/wiki/Who_Shot_Mr._Burns%3F
68.
by gww 5y ago
Nextflow and Snakemake are quite common. I prefer the later as I have a lot of Python experience.
69.
by gww 5y ago
In the biological sciences there is a huge push for the code to be released alongside the paper. Many publications (but not enough yet) include a complete pipeline in a workflow language that downloads, processes the data and generates the
70.
by gww 5y ago
Oh cool thanks, I will check it out!
71.
by gww 5y ago
That would be a great resource. Most of the information I have found ends up being outdated.
72.
by gww 5y ago
I really struggle with this part of Python package development. I have a rather complex C++ library I have been calling with Cython but I am struggling to find the best practices for either compiling the library with setup tools or calling
73.
by gww 5y ago
There are multiple academic startup companies now trying to do cfDNA tests. They have all acquired patents from a paper or two. I would be wary about many of the early stage ones as they are not truly proven or have demonstrated scale.
74.
by gww 5y ago
I bought one for wrist and elbow RSI. I really am enjoying it so far as well. The biggest challenge I am having is finding a layout I like and sticking with it.
75.
by gww 6y ago
Oh I get it that is clever.
76.
by gww 6y ago
I imagine that the tumour would quickly evolve to repress expression, mutate, or completely delete the targetted neoantigen as the neoantigen is probably not required for viability.
77.
by gww 6y ago
I went to disable the online presence indicator for my Reddit account and the "use new reddit" option was magically enabled when I have only been using "old reddit". Has anyone else experienced this? I wonder if they ar
78.
by gww 6y ago
In the life sciences and bioinformatics I have had to wait 2-4 months for first and second round reviews.
79.
by gww 6y ago
I have had a few papers submitted during the pandemic and the time limits given to the reviewer and the time the reviewer actually takes varies drastically. For example, one of my papers was under its second round of peer review for nearly
80.
by gww 6y ago
If the journal is paying a reviewer would there be more pressure in terms of turn around time? Or more pressure to accept contentious papers because the journal expects them to be highly cited or wants to pander to their authors? I also ima
81.
by gww 6y ago
Even before mobile gaming and in-game purchases was a thing. I remember there was a very wealthy player on Asheron's Call Frostfell who paid players to feed his XP chain, bought all of the rarest items such as nexus armour etc etc.
82.
by gww 6y ago
Great channel. I found it a few months ago and have watched all of his videos. I like that he provides enough scientific detail without making it too hard to follow.
83.
by gww 6y ago
I have the same problem. COVID has made it much harder. I finally have some decent publications and was hoping to go to some of the bigger Cancer Genomics conferences this year to try to build a network but it's not the same when it&#x
84.
by gww 6y ago
I have already done the post-doc part. It was so painful that I really don't want to do a second one. There's that glass ceiling in academia when it comes to respect and salary they is very hard to break through without being prom
85.
by gww 6y ago
I agree with you. I think more PIs are realizing that. I know of some who have machine learning scientists that have second jobs in industry. They tolerate it because they still do everything asked of them well and in a reasonable time fram
86.
by gww 6y ago
This is particularly a problem for academic labs looking for bioinformatics specialists. Many of the bioinformatians I know with strong stats backgrounds have taken jobs at banks etc where the pay and benefits are significantly better. It&
87.
by gww 6y ago
If you haven't seen it Lior Pachter at CalTech has been sharing open source / 3d printable designs for lab equipment [1]. [1] https://twitter.com/lpachter/status/1354955229532360707
88.
by gww 6y ago
It's a hard and frustrating career. I work on an academic lab but the chances of me having an independent research program are very low. However, everyone who wants something from you -- especially your PI -- will string you along in t
89.
by gww 6y ago
There is so little emphasis in production software development in bioinformatics and biostatistics. Despite a lot of groups open sourcing their code it's is nearly unusable and not reproducible due to hard coding, ignoring edge cases,
90.
by gww 6y ago
Your description reminds me of the Outer Wilds, the creator wrote a thesis on the game. While it is a bit awkward to get used to the time limit it's part exploration, part archeological adventure, part flight simulator and part platfor

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