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daemonk
searching PlanetScale…
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27 ms
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241.
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daemonk
10y ago
This pretty much applies to any technical field. Good advice.
242.
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daemonk
10y ago
Is this a case of emphasizing aspects of each environment based on some kind of personal bias? The article describes a lack of moral compass in Silicon Valley and an enriching hacker spirit in Beijing. What about the other way around? If yo
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daemonk
10y ago
Sounds like the greatest advantage China has is a non-segmented software eco-system where a few companies dominate the market with apps that can do many things. In contrast to the US where companies focus on just a few key features and user
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daemonk
10y ago
I got to the create a team name step and got an error page trying to submit the team name. I guess your servers are getting the hug of death from hackernews. edit Got in after trying couple more times.
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daemonk
10y ago
I actually just finished a manuscript with overleaf and published it on biorxiv (shameless plug: http://biorxiv.org/content/early/2016/07/25/065789.1 ). Unfortunately, latex isn't used that wide
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daemonk
10y ago
I am in academic research. I want to see if this will be good for my work setting. I tried to sign up and got a nginx bad gatewawy error page :(. I'll try again later if I manage to remember.
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daemonk
10y ago
This is probably an oversimplification, but isn't this kinda just ssh wrapped up in some kind of more user-friendly package?
248.
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daemonk
10y ago
Fuzziness and ambiguity is good for the rational mind. We can't evolve our thinking without mutations.
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daemonk
10y ago
I am a non-high profile alum. While it is true that their fundamental business model is to find people jobs, they don't push that aspect of their business at all. They will try really hard to find you a job that fits you if you want to
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daemonk
10y ago
I have a pair of pet terrapins. Has anyone tried aquaponics with terrapins? They produce a lot more waste than fish. Perhaps that'll allow for more land-mass for growing?
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daemonk
10y ago
I am working with some epigenetics data right now (chip-seq on histone modifications). The main problem I see is that there doesn't seem to be any mature framework for analyzing the data. There are a bunch of disparate methods for diff
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daemonk
10y ago
Doesn't this describe most jobs that require some kind of technical expertise and creativity? I guess the silicon valley mystique/propaganda really works if people expect it to be vastly different from other jobs.
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daemonk
10y ago
I wonder how they removed the genes? I am not an expert in microbiology. I work with mainly eukaryotes, but I am guessing intergenic distances are not a huge factor here? What about spatial arrangement of the genes? Did they generally leave
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daemonk
10y ago
So is this basically "pure" communism? I guess historically, countries we called communistic didn't really adhere to its central idea; or they couldn't do so practically due to the accompanied political/economic ins
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daemonk
10y ago
I work in bioinformatics and have a reasonable amount of experience in the lab. In my perspective, scientific fields like computer science and biology progress in opposite directions. We are starting to see the intersection of the progressi
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daemonk
10y ago
Just bought it. I really like it. One thing that would make this perfect for me is the ability to show stats for specific time ranges within a day. I use my laptop for both work and home. It would be nice to see a set of stats for just 9am-
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daemonk
10y ago
I really like the UI. Is it possible to implement keyboard/mouse movement activity tracking? I don't mean keylogging or anything, but something like key presses per minute while an app is focused or mouse movement in pixels per mi
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daemonk
10y ago
"Building culture" seems like an euphemism for romanticizing the workplace to squeeze more productivity out of employees without spending too much money on supplementing salaries. Interestingly, It's kinda like academia in th
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daemonk
10y ago
I mainly work with eukaryotes, so I don't know much microbio aside from generating vectors. Do we actually know enough about bacteria for this to work? I can see it working for a small number of elements (anti-biotic resistance, promot
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daemonk
10y ago
If this is fake, is this some kind of ploy to flush out the real Satoshi? Or a publicity stunt?
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daemonk
10y ago
Nice read. Product placements didn't really bother me. I just skipped them.
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daemonk
10y ago
This name is obviously a joke name that probably shouldn't be used. Yes, there is a responsibility to maintain a democracy by the governing body. But shouldn't there also be a responsibility on the governed to take voting decision
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daemonk
10y ago
Cool. So they basically took away Cas9's ability to cut, but retained its ability to target specific loci on the genome. Then attached an enzyme that converts the base. Changing the other combinations of bases might be tricky. Not sure
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daemonk
10y ago
I see. I guess near exact match functionality would be great for plasmids where there is a custom sequence inserted. But wouldn't a pre-processing pipeline that either automates annotation of the plasmid based on commonly used motifs (
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daemonk
10y ago
Bioinformatican here with couple years of bench experience. Nice writeup, but what would be the use case here? I would imagine something like automatically annotating motifs/restriction sites and then searching for them would be more u
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daemonk
10y ago
People are down-voting it because it is exact what you said, a gut-level reaction. While it may be a perfectly reasonable reaction, I would think some elaboration on why they didn't like it would be far more informative and probably mo
267.
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daemonk
11y ago
I think the stereotypical thinking is that younger people tend to buy into the culture. Older people tend to not drink the kool-aid. Does the expertise/experience of older people win over younger people who are willing to work 80 hour
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daemonk
11y ago
I work on eukaryotes, so I am not very familiar with bacteria. Is it really this simple in bacteria where you can modify it according to a planned circuit and get the results you expect? I can understand maybe generating simple behaviors li
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daemonk
11y ago
I think the key here is to introduce the concept slowly because saying "stop ageing" freaks people out. A lot of people have this idea of what "natural" means and stopping ageing just doesn't sit right with them. I
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daemonk
11y ago
Are you suggesting that they are just detecting the un-incorporated foreign DNA after CRISPR? I think the fact it has been shown that the knocked-in DNA is inherited to the progeny is strong enough evidence that the DNA was actually inserte
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