COGlory

12 ms·

121.
by COGlory 3y ago
ChimeraX has a VR functionality. Certain modeling programs still support Nvidia's Stereo3D (Coot, PyMOL, Chimera, ChimeraX, and more) which I still use for modeling. That relies on X11 unfortunately, so I'm looking for a new way t
122.
by COGlory 3y ago
Not an expert in that field. I can speculate wildly that I'm not super optimistic. I can say I've seen the narrative around the field start to give way slightly - shifting from "genome is all you need" to "genome is
123.
by COGlory 3y ago
Opening the bio-assembly for 3J31 ate about 8 GB of my VRAM, and 32 of my system RAM, in ChimeraX. Which is actually less than I remember a few years ago. I wonder if the render pipeline has changed a bit. That said, it's still very si
124.
by COGlory 3y ago
I can only guess, but I believe that ChimeraX's rendering pipeline is single threaded (just an empirical guess based on my CPU usage when using it). Additionally, loading that many atom positions requires a huge amount of memory (I rou
125.
by COGlory 3y ago
https://github.com/cryoem/eman2/blob/master/programs/e2spt_m...
126.
by COGlory 3y ago
It's a guided, but automated process. EMAN2 (the software used/partially written by the author), for instance, has a convolutional neural network particle picker. So you can pick a few particles by hand, pick some noise, pick some
127.
by COGlory 3y ago
Yes, at multiple levels. You can do a heterogeneous refinement that takes the structures and solves for n number of averages, trying to use something like PCA to maximize the distances between the averages. Particles get sorted into the a
128.
by COGlory 3y ago
Muyuan Chen is one of (maybe the?) primary developer of the sub-tomogram averaging portion of the EMAN2 software package (linked below in another comment). Typically what you do is take a 3D tomogram (think like a scan) using a microscope,
129.
by COGlory 3y ago
Dolphin is legitimately my favorite KDE program. My experience is that it's a phenomenal productivity tool. Being able to quickly open or close a terminal. How customizable the ordering and appearance and columns are. Easy to manipulat
130.
by COGlory 3y ago
Take away the iPad? Tell them no Youtube on the iPad? Not everything is an engineering problem.
131.
by COGlory 3y ago
Lost in all the discussion about the cultural issues... Who wants to pay for this? Seriously? What value does Gemini provide when it's limited in this form?
132.
by COGlory 3y ago
No. No one trusts Chinese research to be: A) accurate B) reproducible Even in Western journals it's frequently suspect.
133.
by COGlory 3y ago
Next generation computer hardware releases every ~18 months. No matter what you buy it will be "last gen" in like a year.
134.
by COGlory 3y ago
The domain NwAvGuy.com was last renewed in 2023.
135.
by COGlory 3y ago
That poll needs to be explicit about the definition of abortion to be a useful disambiguation. Most people probably don't even consider treating an ectopic pregnancy an abortion, just like how most people don't consider killing so
136.
by COGlory 3y ago
>FTC Obtains $195 Million Judgment, Permanent Ban on Telemarketing and Selling Healthcare Products Against Simple Health Over Charges It Sold Sham Health Insurance This took me about 2 minutes to parse.
137.
by COGlory 3y ago
I'm just saying that fetuses already have some legal protection without breaking the legal system, so we can dispense with "can my embryo be claimed on taxes" jokes. That's all - this post was hit with like 5 of them in
138.
by COGlory 3y ago
In most of the US, that's legally double homicide. The point is for people making snarky comments such as "can the embryo run for president in 35 years?" and "can I claim it on my taxes?" The legal system has differ
139.
by COGlory 3y ago
This simply doesn't apply. If you die, then the fetus dies regardless. It's not wrongful death to have immediate lifesaving medical care, and it's extremely difficult to find a pro-life person that would argue otherwise.
140.
by COGlory 3y ago
Can you name any principle or right that is actually taken to a logical extreme by society? I can own a gun, but not a nuclear bomb. I have free speech, but I can't make fake 911 calls. I can't have soldiers quartered in my hous
141.
by COGlory 3y ago
No one that believes an embryo is a human being also believes IVF is acceptable. At least, not without major cognitive dissonance. Alabama effectively banned IVF with their recent legislation and constitutional amendments. We're just s
142.
by COGlory 3y ago
https://codes.findlaw.com/al/alabama-constitution-of-1901/al... >(b) This state further acknowledges, declares, and affirms that it is the public policy of this state to ensure the protection of the rights of t
143.
by COGlory 3y ago
I would encourage anyone about to make a blithe comment about embryos being people to consider how they would feel about criminal charges against someone who murders a pregnant woman. I'd also recommend everyone read this sentence: &gt
144.
by COGlory 3y ago
What AlphaFold is doing is essentially matching a sequence of amino acids to solved protein structures, albeit dynamically, and with some advanced constraints. In essence, it's not predicting how the protein will fold, but rather, how
145.
by COGlory 3y ago
Just a nitpick, we typically call it a local minima, because we are trying to minimize energy. A stable protein will be at (or near) the minimal energy conformation. Otherwise, I think you are absolutely correct. It's a nearly infinite
146.
by COGlory 3y ago
It's worth pointing out industrial food preparation processes can be patented. Beyond Meat for instance: https://patents.google.com/patent/WO2015161099A1/en
147.
by COGlory 3y ago
This is interesting. I've worked with people like this, met people like this, and heard of people like this. But one thing you're missing is this guy didn't claim to be a highly skilled killer or ex-military. I wonder why. Th
148.
by COGlory 3y ago
>Modern mobile networks work far better if you buy all the gear from one company Do they really? How resilient/robust is such a network? What does "better" mean in this context?
149.
by COGlory 3y ago
>How do you figure that? You're a chief executive of a successful web technology and browser organization, while it looks as though Baker is being removed from the one you previously left. I have no issue with the Rust facts, just t
150.
by COGlory 3y ago
I think it comes off as petty to punch down, and wanted to let Mr. Eich know (out of respect) in case he didn't realize it. But if he realizes it and doesn't care, or just disagrees, that's his decision.

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