COGlory

74 ms·

871.
by COGlory 5y ago
Re: the chimera vs mosaic, that's not particularly true. If I take a known virus and make a single mutation (insertion of a furin site in this case), then I wind up with the same virus, + a furin. If I take that mutated virus, and then
872.
by COGlory 5y ago
This simply isn't true though. Because the jobs pay more than the welfare in most cases, and don't require any skill. Some businesses in town have closed as a result. I know multiple people who would rather scrape by on welfare an
873.
by COGlory 5y ago
People getting paid entry wage at McDonald's were never supposed to be able to afford a house on that. Also housing prices are astronomical, but your numbers are a touch high. I believe the median home price is $600k or so.
874.
by COGlory 5y ago
The Wendy's in Bozeman MT is starting at $17/hr. The McDonalds is starting at $15.50. This is not a wages problem. This is a huge influx of wealthy people to the state that aren't working but are taking up property and servic
875.
by COGlory 5y ago
The Wendy's in Bozeman starts at $17. The McDonald's there starts at $15.50. I know of people working at a clothing store (Athleta) making $22. I think you're extremely off the mark with this comment.
876.
by COGlory 5y ago
Are you implying that having a politician on their board lends them credibility?
877.
by COGlory 5y ago
...picked by Facebook...
878.
by COGlory 6y ago
Then there's Alexander Shulgin. https://en.wikipedia.org/wiki/PiHKAL
879.
by COGlory 6y ago
What about Discord besides network effect makes it a desirable holding? Do they have any technological advantage?
880.
by COGlory 6y ago
The science behind them is well established. The economics just never made sense until now.
881.
by COGlory 6y ago
>Marzari stated that she was not overriding Clark’s “freedom of thought and speech.” >“It is only how he expresses those views privately to [Maxine] and publically to third parties that is affected.” This does not compute.
882.
by COGlory 6y ago
I have no sympathy for any IT department that enforces Teams upon its peers.
883.
by COGlory 6y ago
Yeah this is a parenting failure first and foremost. We don't know what the magnitude of the problem is once that variable is accounted for.
884.
by COGlory 6y ago
No, that was not in this fork, that one is slated for July. This fork was not contentious.
885.
by COGlory 6y ago
The real question is, why do they have to have a sworn enemy? Its not like israel is going to invade them.
886.
by COGlory 6y ago
>We can't just focus on random mutation, we have to think about fixation. Because virus populations don't just evolve in one concerted direction. They evolve /outwards/ in a cloud. It's not simply A to B, it&#x27
887.
by COGlory 6y ago
Not sure what you're referencing as rude. Let me go back to my original hypothesis, and then try to restate your arguments, and you can tell me where I'm restating them incorrectly. My original hypothesis: 1) Major point of differ
888.
by COGlory 6y ago
It's disappointing to see a comment like this get downvoted, especially on HN. The comment appears to find a pretty obvious inconsistency: "why is weed not treated like booze?" and then proposes an obviously off-the-cuff expl
889.
by COGlory 6y ago
I'm just doing a poor job of explaining what I'm trying to say , mainly because I was typing from my phone, and also because it's Friday evening after a long week and I've had a couple beers. And because a lot of this st
890.
by COGlory 6y ago
>You're comparing apples and oranges. 14 mutational sites across a virus with 17k ssDNA genome is not comparable to RATG-13 vs SARS-2, which have not just 1200 mutations different, they're spread out over HUNDREDS of SNPs. If m
891.
by COGlory 6y ago
How was he part of the "insurrection" if he did nothing illegal?
892.
by COGlory 6y ago
Actually, CRISPR/Cas is a fantastic example of lamarckian evolution. What I'm trying to say is that it's not pressure into with evolution, but rather, random mutation + purifying selection = evolution of new traits. Organisms
893.
by COGlory 6y ago
OK so if you go back to here: https://news.ycombinator.com/item?id=26757986 You don't have any molecular biology refutation that I can find.
894.
by COGlory 6y ago
Drop the gatekeeping and appeals to authority and we have an agreement?
895.
by COGlory 6y ago
>And on a small scale, I had that post reviewed by 8-10 working PhD virologists before I posted it as part of the editorial process. Not a true peer review since I know them and it wasn't blinded. But I want to be clear it's no
896.
by COGlory 6y ago
>You spend an awful lot of time attacking me and not very much time attacking my arguments. That's not very scientific of you. I said I had no way to know you were actually a virologist, which I didn't. It isn't really imp
897.
by COGlory 6y ago
Your arguments are not arranged in any sort of logical way against the hypothesis I discussed which set this whole chain off. I examined the one that you claimed refuted it, and failed to see how it applied. If you apply it to my statement,
898.
by COGlory 6y ago
I have to nitpick. I don't believe there's evolutionary pressure to evolve this. Evolution is (going to piss some people off) almost entirely random. There may be purifying selection but that has an entirely different set of prope
899.
by COGlory 6y ago
I'm unfortunately going to give an equally hand-wavy response. There's nothing in there that strikes me as factually incorrect (I could be wrong though because I am not an expert on these viruses). I did a brief genome analysis my
900.
by COGlory 6y ago
I'm going to start off by pointing out that again, almost your entire argument is an appeal to authority, which is not a scientific argument. Oh and add gatekeeping to the list as well, in support of your appeal to authority. As an asi

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