0xB31B1B

10 ms·

61.
by 0xB31B1B 3y ago
In short, it’s a reduction in atherosclerosis associated with obesity and metabolic disorders. In obese people with insulin resistance, some actual fat cells will become “overfilled” with fatty acids and burst. This releases fats into the b
62.
by 0xB31B1B 3y ago
drugs are priced differently country to country and the price has nothing to do with the unit cost to manufacture. The US is the least regulated pharmaceuticals market in the world and drugs here usually cost significantly more than drugs i
63.
by 0xB31B1B 3y ago
Lots of folks in this thread talking about how this comp plan is BS/poorly structured. I don’t disagree, but IMO this is a result of salary/comp deflation in tech. We’re going to see more of these types of plans as companies try t
64.
by 0xB31B1B 3y ago
The main forcing function is gravity. The second function is FAA regs. Third is that most, but not all, pilots will not fly on aircraft that are out of maintenance schedule. The universe of owners/operators that disregard the above is
65.
by 0xB31B1B 3y ago
Outside of their own apple stores Apple is not managing or storing inventory for retail sale. A shipment for bestbuy or Amazon will almost always go straight from the origin to the retailer logistics hub in the US.
66.
by 0xB31B1B 3y ago
Yes. The 3 dominant features are (1) income and (2) ability, (3) alternative opportunities. Highly specialized doctors in the US get paid a lot because they have great alternatives because they are some of the smartest and most driven peopl
67.
by 0xB31B1B 3y ago
It’s not residency slots that gate complex specialties it’s fellowship slots. At the end of residency, a “general surgeon” can do common and basic things like appendectomies. Those that go on to do organ transplants, complex cancer cases, e
68.
by 0xB31B1B 3y ago
Fellowships are the last 1-3 year stint of training for specialist docs. There are unfilled training slots in competitive/complex fellowships in many disciplines. The fellowships are choosing not to train because they don’t have qualif
69.
by 0xB31B1B 3y ago
Black pill for me: the doctors that are paid extremely well (surgeons, complex specialties) are doing work that is extremely challenging and realistically only a tiny amount of people are able to do. Increasing med school and residency slot
70.
by 0xB31B1B 3y ago
There is a 0% chance this is someone gambling. This is a 1000000 sigma event.
71.
by 0xB31B1B 3y ago
The deciding factor here is if the owner can find a cash flow source that covers the mortgage payment, property tax, and maintenance costs. NYC lease rates have surged since the state revamped rent control laws.
72.
by 0xB31B1B 3y ago
1) there are technology workers in solano county that commute to walnut creek or SF. 2) technology workers spend money at local restaurants. Workers in solano county that work in service industry jobs with 60 minute commutes to napa, walnut
73.
by 0xB31B1B 3y ago
No, it’s not. The surplus created by cheap water is captured by the hedge funds buying up artificially cheap water rights then selling foods at market rates for a large profit. Growing alfalfa in California for cows in China or Saudi Arabia
74.
by 0xB31B1B 3y ago
thats great, but amazon pays top of market, so they have more power. You get more money in exchange for less freedom, its not completely explicit, but its also not a secret and its not like they're abusing their workforce by paying the
75.
by 0xB31B1B 3y ago
Huge breakthrough. Energy efficiency is just one gain. This also potentially unlocks major gains in quantum computing, fusion energy, tradition computer chip design allowing another 30 years of moore’s law, batteries with zero energy loss l
76.
by 0xB31B1B 3y ago
the GTM for fake/cultured meats generally goes through restaurants first. its easy to train a few chefs to cook properly, partner with them to make meals that taste great. Much better solution than buying in a grocery and lettting anyo
77.
by 0xB31B1B 3y ago
yea, none of that stuff really matters though. The magic of the MIT type schools is that students are expected to go into entrepreneurial roles, found companies etc in a way that is not the norm at schools like CMU. The peer set at MIT will
78.
by 0xB31B1B 3y ago
San Francisco, where this article is about, is spending more than 75k USD per homeless person per year on homeless services. The issues is not a lack of compassion of city residents or the collective residents of the city shouting "pul
79.
by 0xB31B1B 3y ago
There were a few hundred shelter beds available last night in SF to anyone who wanted to sleep indoors. The problem is the people who sleep outside the library don't want to sleep in shelter, because the shelters don't allow drug
80.
by 0xB31B1B 3y ago
we're far far beyond "trampling on freedom of movement" in SF. We need to enforce basic laws and pro social behaviors like "don't poop on the street", "dont smoke meth within 500 feet of an elementary scho
81.
by 0xB31B1B 3y ago
Thats great, the library in question has to call the police multiple times per week for various issues caused by the meth addiction homeless who occupy it. It has completely ruined the concept of library for everyone who isn’t a drug user.
82.
by 0xB31B1B 3y ago
Correct, ~75% of homeless people are "invisibly homeless", don't have drug use issues, aren't criminals, take showers and don't practice antisocial behaviors. The problem is that the 25% of homeless who are drug add
83.
by 0xB31B1B 3y ago
Library wifi is not a homeless service. An 24 hour open seat on a subway is not a homeless service. Parks where children play is not a homeless service. Public goods being overtaken by an antisocial drug users in the name of homeless suppor
84.
by 0xB31B1B 3y ago
I hate local beers. Local wine makes sense, there is terroir, a sense of place etc. Local beers are just some weird competition to see who can make the hopiest bitterest beer. I don't want to try a new lager every time I cross county l
85.
by 0xB31B1B 3y ago
In the process of going public, the SEC is not evaluating if the business model of a company is legal, it is evaluating if the company is exercising the proper financial disclosures to market its securities to the public. There are a bunch
86.
by 0xB31B1B 3y ago
Going public regs is not about validating business practices, it’s about validating disclosures to investors. Entirely different things.
87.
by 0xB31B1B 3y ago
There is 80 years of case law in the US about what is and isn’t a security. The SEC is applying the 80 years of case law history to this action. It’s not an SEC land grab.
88.
by 0xB31B1B 3y ago
Ransomware. The ransomware economy is powered by crypto, did not exist before crypto, and would not exist without the key feature of crypto, that it allows transfer of money without KYC.
89.
by 0xB31B1B 3y ago
It’s a job, not a pension. The goodwill lasts a quarter, not 20 years.
90.
by 0xB31B1B 3y ago
RE #2, the main political issue in SF at the moment is that the homeless advocacy non profits want permanent supportive housing as the only solution, they advocate against shelters temporary group and sober housing, and they also advocate a

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