In short, it’s a reduction in atherosclerosis associated with obesity and metabolic disorders. In obese people with insulin resistance, some actual fat cells wi

In short, it’s a reduction in atherosclerosis associated with obesity and metabolic disorders. In obese people with insulin resistance, some actual fat cells will become “overfilled” with fatty acids and burst. This releases fats into the bloodstream and also releases inflammatory chemicals called cytokines. This is the process by which people get fatty liver disease. Both the fatty acids and the cytokines contribute to atherosclerosis, or hardening of the arteries. Causing a reduction in fat mass reduces the rate at which these cells burst and the associated coronary events, but it does not “fix” the arteries if they’re already damaged.