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Viagra improves brain blood flow and could help to prevent dementia
- Havoc 2y agoPresumably it would need to be pretty continuous though? So uhm like micro dosing ?
- silenced_trope 2y agoI take 4.5mg cialis (tadalafil) every day. I think a lot of people do. Viagra is slightly different of course. Both "hims" and "blue chew" now offer a daily mint "multivitamin" of tadalafil.
- jjallen 2y agoYou take it for this purpose or why?
- QuantumGood 2y agoIt is prescribed for benign prostatic hyperplasia (BPH; an enlarged prostate) which include difficulty urinating—not just for ED
- koolala 2y agoouch thank you for explaining your usecase
- pasquinelli 2y agonow you have my attention.
- beachy 2y agoJust hijacking to add a public health warning about BPH. Like many men as they get older, I was getting up several times a night to pee. Thought I would just put up with it until it got worse. I went on a yacht for the weekend, drank quite a few beers and crashed to sleep. I awoke to find out I couldn't pee at all. I can't describe how painful things were by the time I staggered into the emergency department that evening. Definitely the worst experience of my life. A few weeks later a guy was winched off a boat by helicopter with the same condition - one of his mates had been tasked with catheterising him using the rubber fuel hose from the boat's engine, but was unsuccessful. If you are having trouble urinating, seek medical attention - don't ignore it.
- justinc8687 2y agoIs there some correlation to boats or just happenstance?
- beachy 2y agoJust coincidence, situations where one might drink too much and be isolated from medical care.
- barrenko 2y agoIgnoring prostate issues for 6 months got me to the edge of sanity - I was 26 then and was told there was no way I have prostate issues.
- 2-3-7-43-1807 2y agowhy on a yacht, though? i have a similar problem. shy bladder plus tense pelvic base. maybe even somewhat increased prostate (i don't know). so peeing is always something i need a little privacy for. but everytime i'm scuba diving plus out with a boat it's like my prostate is locking up completely. extremely weird and uncomfortable feeling. on those small boats there is never a toilet but there are sneaky options that in theory should work but don't. so i'm wondering if the wavy motion might have something to do with this problem.
- petereddy 2y agoI take it on doctor’s orders to recover from prostate cancer. Improving the circulation in that area should help rebuilding tissue.
- paiute 2y agoThere are many off label uses. Pulmonary Hypertension for one.
- astrange 2y agoIf you want to pretend to be old, Strattera gives you the effects of this as a side effect.
- hombre_fatal 2y agoAnother weird effect was that my ejaculation and orgasm were seconds apart. Don’t remember which came first (pun). Hated that drug.
- QuantumGood 2y agoBPH smptoms I started having in my '60s turned out to go away when I stopped taking antihistamines for seasonal allergies.
- tomcam 2y agoLooks like 5mg viagra is 10%-20% of the minimum recommended dose for viagra's original purpose
- saulpw 2y ago10mg works really well in my experience.
- Scoundreller 2y ago5mg of tadalafil would be 50% of the typical “as needed” dose for its original purpose
- loeg 2y agoGP is talking about cialis (tadalafil), a completely different drug. It is dosed differently from viagra (sildenafil).
- tomcam 2y agoThanks! I thought they were the same
- snakeyjake 2y agoI do the same because 20 years ago a roadside bomb blew up next to the vehicle I was riding in and caused it to roll over and down an embankment and the repeated impacts compressed my lumbar discs which after about 10 years manifested as degenerative disc disease at L5-S1 and a series of disc bulges and scar tissue build-up up and down my lumbar region that compressed the nerves leading to my genitals and ultimately led to a spinal fusion of that area... ...and a low dose makes it so my penis functions normally. It's fantastic, really.
- the_arun 2y agoIt needs prescription, correct?
- koolala 2y agoummmmmm... no offense if you have dementia and i have no easy way to ask about it, sorry this question is personal and you could easily just be asking for a friend
- cactusplant7374 2y agoIt's possible to order it from Indian pharmacies or one can pick it up while on vacation in the third world.
- Scoundreller 2y agoWhich is why every package I get from India (to Canada) goes through heavy inspection, to the point that most/all Indian pharmacies just won’t ship here anymore.
- salad-tycoon 2y agoYes, but how do you know what it really is? Plenty of legit generics have been found to be complete bunk,(1) let alone gray market ED drugs. Other generics have high levels of cancer causing contaminates. Eg TMAO in metformin, chantix, ranitidine, and more. 2 You can also buy these things as research chemical but same question as above. Always remember, made in USA is likely a misdirection. You buy this stuff in bulk off of Alibaba like sites, buy some made in USA containers, repackage it in the USA and now you can claim the whole thing is “made in USA.” Some of these places will list chemical analysis of their drugs but who knows what they tested what they send? Also, when did they test, who tested it? Etc. would love to hear if anyone has figured this out. Just some quick references off the top of my head, 1 - bottle of lies, book or Ted talk https://m.youtube.com/watch?v=si2M93gZy1E&pp=ygU5Ym90dGxlIG9mIGxpZXMgcmFuYmF4eSBhbmQgdGhlIGRhcmsgc2lkZSBvZiBpbmRpYW4gcGhhcm1h https://m.youtube.com/watch?v=si2M93gZy1E&pp=ygU5Ym90dGxlIG9... 2-valisure, commercial entity that tests for contaminants. https://www.valisure.com/ https://www.valisure.com/ Also labadoor, consumerlab.com and others 3- John Abramson did an interesting Rogan interview a while back
- bell-cot 2y agoExpect a new tsunami of Viagra spam in 3...2...1...
- jagged-chisel 2y agoI bet you were at least sixty seconds late
- samstave 2y ago[dead]
- boguscoder 2y agoHmm I thought viagra improves blood flow in opposite place but 2 for price of 1 is great too
- andrewstuart 2y agoIts all the same.
- Izikiel43 2y agoDifferent head
- sva_ 2y agoI think it just causes vasodilation anywhere in the body?
- Spod_Gaju 2y agoYes, pretty much everywhere but the eye. https://www.proteinatlas.org/ENSG00000138735-PDE5A/tissue https://www.proteinatlas.org/ENSG00000138735-PDE5A/tissue
- AbstractH24 2y agoThis makes me wonder -- why do things like stimulants, caffeine, and cold medicine help people think clearly? Aren't they vasoconstrictors?
- GlickWick 2y agoWasn't this class of medication originally for cardiovascular issues, and the whole ED mitigation was a happy marketable accident?
- mikercampbell 2y agoI vaguely recall an anecdote about athletes using it for performance improvement, and getting a slightly different stat buff
- brandall10 2y agoIt's commonly used in bodybuilding competitions.
- lukan 2y agoNow I cannot get that picture out of my head. A crowd full of bodybuilders in tight shorts and all on Viagra doing workouts. Each to his own I guess..
- idiotsecant 2y agoI'm pretty sure you don't just get random erections unless you're engaged in activity that you find sexually stimulating. ...so yes, probably.
- rs_rs_rs_rs_rs 2y ago> I'm pretty sure you don't just get random erections unless you're engaged in activity that you find sexually stimulating I think that's the case for Cialis but Viagra should make you "pop" regardless of what activity you're doing.
- Frost1x 2y agoThat’s not how it works at all. As someone with recent onset of ED taking viagra regularly, it’s been fantastic but it just makes me function like I should. It takes about an hour to take effect (usually less for me) and lasts a little over 4 hours with some lingering effects for several hours later, with diminishing effects towards the 4 and above hours. If I’m sexually stimulated during that time physically and or mentally, everything works like it should (erection). If during that time even when I would normally see peak effects around the 50 min to 90 min mark I’m driving or doing taxes or whatever non-sexually stimulating activity one might do, no erection at all.
- bouncycastle 2y agoAll you need is regular exercise to improve blood flow
- koolala 2y ago[flagged]
- mpenick 2y agoSimple solutions to hard problems seem to be falling out of favor.
- Spod_Gaju 2y agoActually, exercise lowers cGMP (and low cGMP is what Viagra reverses) so your "simple solution" is actually totally wrong.
- larsrc 2y agoHave done regular exercise to improve my Long COVID state for 6 months now. It has helped, but it has its limits too. If I overdo it, I get worse, but I can't always tell until later. And other health issues are limiting what forms of exercise I can do. Hard problems rarely have one simple solution, or they wouldn't be hard, would they?
- rsynnott 2y ago> The OxHARP trial was a meticulously designed double-blind, placebo-controlled study involving 75 participants who had experienced a minor stroke and showed signs of mild to moderate small vessel disease. I mean, I think if going for a walk were a magic bullet for stroke rehabilitation, someone would have noticed by now.
- SamPatt 2y agoI'm not knowledgeable about stroke rehabilitation specifically, but the benefits of walking are extremely robust. Especially if you're talking about the difference between a totally sedentary lifestyle and one which includes a substantial amount of walking.
- koolala 2y agodeleted?
- a_wild_dandan 2y ago“…involving 75 participants who had experienced a minor stroke and showed signs of mild to moderate small vessel disease.”
- mikercampbell 2y agoI had my hopes up, but there is the kicker
- deleted 2y ago[deleted]
- ablyveiled 2y agoViagra increases the effect of nitric oxide, which is bad stuff when it gets into cytochrome complex iv in the mitochondria (IIRC). I would personally suspect based on that, that its effects on brain health would be negative in spite of blood flow.
- francisofascii 2y agoNitric oxide bad for you? Pretty sure it is good for you ,otherwise super foods like beets and leafy greens would be bad for you.
- fnordpiglet 2y agoNitric oxide is a crucial part of the biology of life, especially animals. Viagra does not specifically impact the amount of nitric oxide in the body or the nitric oxide cycle mediated by arginine. It instead enhances the effect of NO in the smooth muscle. I would not worry about nitric oxide in general as it’s crucial for the basic functioning of your body.
- Dylan16807 2y ago1. "Bad stuff" meaning what? 2. There's no such thing as increasing "the effect" of such a nonspecific chemical as nitrogen oxide. There's tons of effects, and it increases some of them. Also, can the active ingredient get into mitochondria?
- sva_ 2y ago> The OxHARP trial was a meticulously designed double-blind, placebo-controlled study involving 75 participants who had experienced a minor stroke and showed signs of mild to moderate small vessel disease. Each participant received sildenafil, a placebo, and cilostazol (a similar drug) over three-week periods in a randomised order. I feel like dudes will know if they got Viagra or not? It doesn't seem like cilostazol has the same kind of effects on them, or does it? So is it really a placebo?
- saulpw 2y agoViagra doesn't "make" you hard, you still need sexual stimulus. I've taken it and then the sexual opportunity fell through, so I went back to coding or whatever, and I didn't notice anything different.
- arresin 2y agoDang, that is a sad tale.
- wumbo 2y agoSevere warning. I have no sexual problems and took a viagra once. It definitely was automatic and persistent. It was terrible. It wouldn’t even go away when I was done with it.
- paiute 2y agoPseudoephedrine
- ThrowawayTestr 2y agoYou shouldn't mix uppers and downers.
- paiute 2y agoIt’s one of the things they might give in a hospital for it.
- spencerchubb 2y agoBoss: You look... particularly excited to be working today Me: I'm just trying this new technique to boost productivity
- luxuryballs 2y agoyou seem to be working hard today
- xtracto 2y agoOh man...
- ta4343 2y ago[flagged]
- anigbrowl 2y agoUsername checks out
- spencerchubb 2y agoMy username is my legal first and last name lmao
- anigbrowl 2y agoNominative destiny strikes again!
- mpenick 2y agoSaunas, hot baths, and excercise improve blood flow.
- demondemidi 2y agoThis is America: we demand a low-effort, overpriced solution, preferably in pill form.
- senordevnyc 2y agoNot everyone on HN is from the US, and the study in question is from the UK...
- demondemidi 2y agoDo you have jokes where you live?
- Dylan16807 2y agoSaunas and hot baths are low-effort too, but they get pretty expensive time-wise. And these pills are pretty cheap.
- houseplant 2y agothink about the main consumer base for viagra, and then think about who makes the majority of economic/financial decisions in this country.
- pram 2y agoI’ve read about people using tadalafil as a nootropic in the past. Is there even a difference? It’s so easy to get a prescription these days might be worth a shot.
- simple10 2y agoTadalafil (Cialis) can be useful for dealing with depressive symptoms. It's commonly used in nootropic circles. With both viagra and tadalafil, they can negatively effect sleep. So it's hit or miss for a lot of people depending on depressive or anxiety symptoms. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7306377/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7306377/
- anigbrowl 2y agoIt's thought to improve neuronal density in the hippocampus and also (higher p) to increase bone density. A lot of bodybuilders and athletes use it for increased blood flow benefits, partly because it seems to have fewer side effects then sidenafil (which can cause mild retinal damage leading to a blue tint in the vision; probably why Pfizer used a blue tint in all their advertising). I have no personal experience with it but the theory seems sound. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7321982/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7321982/
- xgkickt 2y agoI’d like to see how this effect from Sildenafil compares to increased NO levels from eating beets.
- Aerbil313 2y agoIIRC the benefit of viagra comes from increased NO in blood. You naturally get no when you breathe from your nose. I'd like to see a research on viagra use and mouthbreathing relation.
- CoastalCoder 2y agoIf nothing else, you're making me imagine some new scenes involving Dwight Schrute :)
- debo_ 2y agolooks at pants I see you've been beeting off ... Sorry
- paiute 2y agoThis is how i figured out NO would help my heart. Eating cereal colored with beet powder. If i understand the magic happens when it combines with saliva. So chewing beets might help.
- 01100011 2y agoAlso arginine and/or citrulline.
- Arthanos 2y ago50mg 3x a day, according to the study: https://www.ahajournals.org/doi/10.1161/CIRCRESAHA.124.324327 https://www.ahajournals.org/doi/10.1161/CIRCRESAHA.124.32432... Seems high to me, but I've never taken the drug. I assume most people take it just a few times a week for it's intended use? Is anyone aware of research that shows positive benefits to health at recreational doses?
- Aurornis 2y agoThat’s a standard dose. 3X per day is because it has a short half life. > Is anyone aware of research that shows positive benefits to health at recreational doses? Recreational doses? What does that mean? Excessive vasodilation isn’t going to be fun. You actually need some vasoconstriction to balance your blood pressure. Too much and you’re just going to get headaches and lightheaded. Excessive vasodilation would be expected to worsen cognition.
- ezekiel68 2y ago> Recreational doses? What does that mean? I mean, we don't need to act obtuse here in the name of pedantry. Commenter was clearly referring to occasional use for on-label indication.
- antonyt 2y agoGiving the parent the benefit of the doubt, they probably were confused by the idea of people taking these pills to get high. That's generally what is meant by the term "recreational use" when it comes to drugs.
- AbstractH24 2y agoSo Extended Release Sindafil is about to hit the market hard? Reminds of me how ER Guanfacine was brought to market as and ADHD drugs. Why invent new drugs when you can put new wrappers on old ones?
- deleted 2y ago[deleted]
- pbj1968 2y agoI used to buy it over the counter in Mexico for recreational purposes, now I have some ancient prescription I don’t need that’s renewed annually for free. A stiff breeze will work, it’s actually remarkable. It will totally make your skin flush and make you feel light headed, not surprised by any of this.
- Spod_Gaju 2y agoIf this is true they altered zinc metabolism might play a role in dementia since zinc is the cofactor for PDE5, or that people who do not make enough cGMP are prone to dementia (which also means they might be low in GTP and GTP regulates glucose-insulin secretion so...) So I think they can do better then "here is a pill give me more money".
- WalterBright 2y agoFirst NIH said it does: https://www.nih.gov/news-events/nih-research-matters/viagra-associated-reduced-risk-alzheimers-disease https://www.nih.gov/news-events/nih-research-matters/viagra-... Then it doesn't: https://www.nih.gov/news-events/news-releases/nih-dream-study-finds-viagra-cialis-do-not-reduce-risk-alzheimer-s-related-dementias https://www.nih.gov/news-events/news-releases/nih-dream-stud... Then it does: https://www.ox.ac.uk/news/2024-06-07-sildenafil-viagra-improves-brain-blood-flow-and-could-help-prevent-dementia https://www.ox.ac.uk/news/2024-06-07-sildenafil-viagra-impro... Who knows what to believe.
- throwup238 2y agoI’ve always been taught that “a wank a day keeps the doctor away” so I believe it.
- hulitu 2y agoI guess it depends on the Doctor. /s
- pcloadletter_ 2y agoMaybe these studies are particularly hard
- CydeWeys 2y agoThey certainly are hard, because dementia is something that develops over years if not decades. Anytime it takes that long to do a single iteration of your experiment, it's hard!
- jfoster 2y agoDoes it need to be, though? You can survey healthy but senior populations about their habits, and then over the following years track what happens. If medical records were public, the answers could even be in those for any medicines that are prescription based. You could then make statements like "A% of patients who took drug B within C years did/didn't develop disease D".
- doubloon 2y agoyou know what else would? walkable cities more time off from work more third spaces less air pollution less inequality of course none of that "increases productivity or GDP" so the ruling class won't consider it. of course when they start dying like Japan with low birth rates, their 'solution' is to have a government funded dating app instead of doing the obvious.
- astrange 2y agoLess air pollution does increase productivity (air pollution is actually really bad for your mental performance, it's a surprisingly strong effect) and it seems to me "the ruling class" does consider it seeing as the Clean Air Act exists. Btw, Japan has walkable cities of course but also has low inequality (but not so high wealth). Approximately nothing is known to increase birth rates except for being highly religious though; it seems they mostly collapse when people have anything else to do for fun besides have sex. So basically it's caused by being on your phone too much.
- arcimpulse 2y ago"Japan doesn't have walkable cities" is not a logical conclusion one can draw from the grandparent.
- ezekiel68 2y agoNah, man. I'll take the Capitalism and the pills.
- kredd 2y agoGiven the opportunity, people will do anything else than have more than 2 children, which is the requirement to increase the population. There’s just better stuff to do than spend multiple years taking care of the baby. Any argument other than “for the greater good” won’t sound reasonable to educated population. Talking to my friends, especially women who already have a child, they keep mentioning the opportunity loss when you go through pregnancy and birth (career, vacations, personal growth and etc.). You can call it selfish, but it’s the reality and nobody wants to fall behind. Everything you mentioned is great, and I support it, but I doubt it’ll convince young people to sacrifice at the very minimum 6 years of their life (pregnancy + first year).
- hkt 2y agoAh, finally, Rupert Murodch's secret!
- deleted 2y ago[deleted]
- elzbardico 2y agoWell. too sad I can't take it. It gives me terrible heartburn (an acute stomach pain, not a heart related condition) that only partially responds to anti-acids such as Alka Seltzer. Also, extremelly stuffy nose, to the point where basically I need to breath by the mouth. And the red eyes, eyes as red as if had just smoke the biggest and strongest joint ever. Yes, I tried to use it recreationally a few times. It is not worth the pain for me. And then the dosage in the study: 50mg 3X times a day? I am not sure I could even survive the first day. Did I mention the headaches too? EDIT: Before someone asks... At least the on-label effect works really well in a recreational setting for me. But it is kind of funny to have persistent carbon-steel erections when you're feeling miserable with stomach pain and can't breath well. Doing oral sex with a stuffy nose is... interesting.
- Scoundreller 2y agoSildenafil is fairly short acting, so that’s probably the reason for 3x/day (but a better choice if you don’t need a whole day of effects because of its side effects like sinus congestion). Tadalafil (Cialis) would probably be a better choice, and is used at daily (but reduced) dosing for prostrate issues.
- flatline 2y agoViagra is prn, you should not take it 3x/day. Cialis is a daily dose.
- elzbardico 2y agoI was talking about the regime used in the study. If you read the article you'll find that
- talldatethrow 2y agoWere you taking authentic or internet genetics from China/India? Ive gone through a decent amount of generics over the years, from several sources, and even though the label is the same, they almost all act differently on me. Some give me a flushed red face. Some cause a dull headache. Some don't cause anything negative thank God. They all work though. I think the Indian/Chinese ones are laced with garbage and what I feel depends on what else was in there.
- adolph 2y agocanned ham health benefits still elude science
- aaron695 2y ago[dead]
- largbae 2y agoI always wonder if there is a circular logic flaw in survey studies of recreation and dementia: could it be that the folks who are chasing Viagra or running marathons don't get dementia, because the ones with dementia don't pursue these activities?
- standardUser 2y agoThe 3x daily dosage is surprising to me because the one notable warning that comes with the prescription is to never take it more than once in a day. In fact, I would go as far to say that if you've been prescribed Viagra the only things you know about it are: it will help you get boners, you should talk to a doctor if you have a heart condition, and you should never use it more than once a day. The warning seemed extra ominous because it was basically the only warning, so I adhered to it fairly strictly at first. About a year later I talked to some gay male friends and they all said that was ridiculous, that they freely take it multiple times per day, and I that should too. So now I do (as needed) and it's worked very well. Plus, the subscription I get through Hims sends me a giant bottle of 20mg pills (at an unreasonably high cost) so I am able to easily dose myself instead of being given a one-size-fits-all dosage, like we get with most medications. My low dose is 3 pills and my high dose is 5 pills. Now there are many options beyond Viagra including a ton of intriguing combination drugs that use multiple erection drugs and/or other drugs with tangential effects. But I like that I know how Viagra works for me personally based on experience. I think we all underestimate how much drugs very from person to person. Plus, now that I think about the lack of warnings that come with Viagra, it actually seems like an unusually benign drug.
- UberFly 2y agoA typical dose of Viagra is 25,50 or 100 mg, so your 3-5 doses of 20 mg isn't even atypical. Also, there are plenty of warnings that come with Viagra usage. You may have not taken the time to read them.
- nothrowaways 2y agoWhat a coincidence
- fny 2y agoViagra has also been shown to reduce period cramps. https://pubmed.ncbi.nlm.nih.gov/23925396/ https://pubmed.ncbi.nlm.nih.gov/23925396/
- ofrzeta 2y agoOne trial with 62 patients and then "Since we did not meet our sample size due to the loss of funding and could not confirm our primary hypothesis, larger studies of longer duration, likely multi-center, are needed to confirm the findings from this study. "
- kabes 2y agoIt also increases blood flow to the scalp, which helps against hair loss.
- madmask 2y agoTry some citrulline
- deleted 2y ago[deleted]
- bionhoward 2y agoJust a word to the wise, viagra can cause tinnitus by putting too much blood through tiny vessels in your ears. Be careful of high doses while hydrated and exercising
- noduerme 2y agoisn't, er, vigorous exercise part of what people expect when they take viagra?
- galdosdi 2y agoDepends. The kind of exercise you're thinking can be done vigorously and for a long period -- or, for some people, it could be a quick 5-10 minute thing that feels vigorous but really doesn't involve that much muscular effort.
- sushid 2y agoIt's common to have a 1 hour running or a lifting session 3-4 times a week but kudos to you and/or my condolences to your partner if your vigorous exercise lasts that long every time.
- alfiedotwtf 2y agoOff-topic but related… I started Vyvanse about 3 months ago and the only negative side effect so far is tinnitus. It’s bloody loud :(
- hooverd 2y agoIt can also be caused by SSRIs and NDRIs and benzos! Great side effect if you're already feeling depressed. Although benzos can also help, depending. I think 80% of cases are a brain thing and not an ear thing, but because ENTs and audiologists have exactly one hammer (hearing aids), we get fuck all for research.
- alfiedotwtf 2y agoYeah, definitely a brain thing. Once it wears off, no more tinnitus :) But I’d rather tinnitus and focus, than silence but scattered!
- cpill 2y agoI wonder if it would help with the brain fog of long Covid...?
- larsrc 2y agoMe too! This small study suggests so: https://clinicaltrials.gov/study/NCT00598585 https://clinicaltrials.gov/study/NCT00598585
- treprinum 2y agoIt also seems to cause melanoma, so... Pomergranate/beetroot/garlic seem safer. Arginine/citrulline perhaps as well (all of them increase NO in the blood). https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4178948/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4178948/ https://www.drugwatch.com/viagra/melanoma/ https://www.drugwatch.com/viagra/melanoma/ "In 2014, a study published in JAMA Internal Medicine found that the use of sildenafil, more commonly known by its brand name Viagra, within 3 months prior to the study’s start increased the likelihood of developing melanoma by as much as 84 percent.'
- loeg 2y agoIt is associated with increased risk of melanoma, but not known to cause it. The third variable is expected to be lifestyle / socioeconomic. https://jamanetwork.com/journals/jama/fullarticle/2338254 https://jamanetwork.com/journals/jama/fullarticle/2338254 > Men taking PDE5 inhibitors had a higher educational level and annual income, factors that were also significantly associated with melanoma risk.
- treprinum 2y agoStill, it's a food for thought. I know correlation is not causation but there might be some link that hits some folks unexpectedly hard. I was taking sildenafil to improve brain hypoperfusion from long covid and one day a fast growing mole appeared on my arm that reached 2cm diameter in a few days - the suspicion was on nodular melanoma or pyogenic granuloma and it turned out to be the latter. I stopped taking sildenafil immediately. I am in the socioeconomic group they mentioned.
- seydor 2y agobetween this and cialis helping with prostate cancer, i wonder if the erection is just a side effect
- AbstractH24 2y agoOne that is very profitable
- pylua 2y agoMaybe now viagra opens up to older women, not just men ? It will double their market ?
- bitwize 2y agoSo it works as well for the big head as it does for the little head. Interesting, but somehow I feel I should have figured this was the case.
- dkekenflxlf 2y ago@ALL: Guys (esp!), for real-pros, Viagra is a toy - instead, they use Taladafil/etc. (Source: Boner all day _actually_ hurts ;-)
- black_13 2y ago[dead]
- jgalt212 2y agoThere's a joke / counterpoint in here about men with erections thinking less clearly than men without erections.
- martin82 2y agoEating healthy (low carb), working out, and thus preventing insulin resistance prevents dementia. But big pharma is never going to tell you that...
- audiometry 2y agoWould cialis likely have the same benefits?