zosima

15 ms·

121.
by zosima 3y ago
Yes, the zoonotic origins of e.g SARS and MERS were found shortly after the outbreaks. In fact COVID seems somewhat unique amongst modern maladies to not have a clear zoonotic origin.
122.
by zosima 3y ago
There may have been brought even closer relatives of covid-19 to Wuhan by lab personnel. We don't know as for unknown reasons the database of specimens collected by the Wuhan lab was taken down in September 2019. The distance in years
123.
by zosima 3y ago
The Huanan Seafood market paper has been heavily critized. Especially the fact that covid was not found in a single animal sample does make the evidence rather weak. In addition it seems that the lack of sampling from outside the market and
124.
by zosima 3y ago
And crucially, researchers from the Wuhan lab were studying bat virus samples from Laos, before covid. https://www.business-standard.com/amp/article/current-affair...
125.
by zosima 3y ago
Some points: 1. Depression is measured by severity on the MADRS scale. But the Ketamine group seems to have started out less depressed than the Placebo group. Thus the placebo group had further to fall. Normally this will be adjusted away w
126.
by zosima 3y ago
Why not apply this principle when making laws?
127.
by zosima 3y ago
FDA was pushed for, I think, over six years by laws to allow over-the-counter hearing aids. I don't know why they even started regulating them. There is no credit here, whatsoever, for FDA.
128.
by zosima 3y ago
But there's also plenty of negative feedback processes. Why assume there'll be extreme runaway apocalypse from the warming.
129.
by zosima 3y ago
What resolution does ice core records have? Do they really show year-over-year change or are the core records being smoothed through natural processes?
130.
by zosima 3y ago
Yes, Aducanumab may very well have had mild efficacy in the high dose group. But clearly the two newer drugs appear superior. Especially, when considering the side-effect profile. It will be exciting to see how efficacious these amyloid-bet
131.
by zosima 3y ago
Antibiotics has worked well, since its invention and continues to work very well to this day. Sure, resistance to antibiotics is an occasional problem. But it's also a problem that doesn't seem to grow much worse over time. Proble
132.
by zosima 4y ago
No, the fact that amyloid-beta or at least its precursor protein APP is causative in Alzheimer's disease is based on very solid science, with a huge amount of genetic evidence behind it. Lecanemab an antibody that binds to amyloid-beta
133.
by zosima 4y ago
This looks like solid work. Still need more research, but if I suffered from cardiac problems or diabetes, I'd stay away from erythritol and other sugar alcohols for the time being.
134.
by zosima 4y ago
How is the ecology more sustainable and pleasant with a different amount of CO2 than 450ppm? What is the optimal concentration of CO2 and why?
135.
by zosima 4y ago
Germany declared war on Russia which was allied with France. And Germany did not declare war on any of those countries out of will, but due to an alliance with the Austro-Hungarian empire. The situation is not even remotely comparable.
136.
by zosima 4y ago
> I am guessing that if we applied a similar model to Russian and English, the model would indicate there is an inherent bias against the west in Russian and a bias against Russia in English. That is all were seeing here. It isn't a
137.
by zosima 4y ago
The C standard could easily make dereferencing a null pointer implementation-defined behavior. And even more critical: Signed integer overflow should be implementation defined, and each implementation do something sane (different from assum
138.
by zosima 4y ago
People are getting a woefully inaccurate picture of the world, which make us all worse off (because massive numbers act deluded, due to being fed bullshit). Making sure that AIs don't go completely bonkers for the powers that be, is ul
139.
by zosima 4y ago
Whether they create more harm than good, I don't know. I'm on the fence. But they definitely cause a lot of harm, and it shouldn't be a secret that foster homes are the most dangerous homes for kids. Here is some statistics a
140.
by zosima 4y ago
Most people don't wear life-vests on dry land. Severe flu is very, very rare in most healthy people below 60 or 70. It's simply not a real risk, compared to driving to and from work.
141.
by zosima 4y ago
I agree, I think the politicization of the covid-vaccine, and almost forced vaccination in many countries and places of e.g. people younger that 20-30 years who would stand to get no benefit from the vaccine whatsoever has created an anti-v
142.
by zosima 4y ago
Lecanemab had an extremely strong effect, from a statistical point of view. The average clinical efficacy could be stronger. But Lecanemab is definitely the largest step in Alzheimer's disease research in a very long time. Well, when y
143.
by zosima 4y ago
Because the results of this trial is extremely convincing. The result of the Adecanumab trials was fairly unconvincing, and it was quite possible that the positive results were due to a fluke. The second reason is that Adecanumab did not (a
144.
by zosima 4y ago
There is very good genetic evidence that amyloid oligomers are causative in the rarer dominantly heritable types of Alzheimer's disease. The recent positive results of a Lecanemab phase III study, furthermore provides strong evidence t
145.
by zosima 4y ago
Yes, clearly the Mayas were a peaceful society living a perfect harmony with themselves nature and other tribes, and no regular practices contrary to modern sensibilities. https://en.m.wikipedia.org/wiki/Human_sacrifice
146.
by zosima 4y ago
Also in the Soviet Union most people publishing and spreading unsanctioned works, did so because they did not propagate the blessed and (therefore) popular views of the party. How strange.
147.
by zosima 4y ago
Many people have had the idea that fascism will only be able to make entrance into America under a different name and guise. And most likely then disguised as anti-fascism. And currently it seems fairly clear. I don't think most of the
148.
by zosima 4y ago
So please tell, by what statute or mandate is FBI helping to enforce twitter's terms of service?
149.
by zosima 4y ago
No, you wouldn't expect anything like that at all. Nobody passing kindergarten would write down something so blatantly illegal.
150.
by zosima 4y ago
I am quite sure, that if a sufficient bounty was given out for developing new kinds of antimicrobials, they'd be developed in no time. The problem is that cost and risk of development and trials is too large for the current rewards, an

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