vibrio

28 ms·

331.
by vibrio 9y ago
Mine was a hedge fund with a sports franchise attached.
332.
by vibrio 9y ago
It’s true, if you cure Alzheimer’s you will probably be worth hundreds of billions of dollars, but scientifically Pharma is groping in the dark at this point in time. The last decade or so has had a series of extremely expensive last stage
333.
by vibrio 9y ago
Probably the most expensive identification of aspergillus sp. ever.
334.
by vibrio 9y ago
This is interesting but my understanding of blockchain is limited so: Aren't all transactions 'encoded' in the blockchain? If so why can't the coins be found? If not, what does the blockchain "record"?
335.
by vibrio 9y ago
I came here to say this. Knowing the difference between an investment and a gamble is my most important rule in money management. There is nothing wrong with gambling-just know when and to what extent you are doing it.
336.
by vibrio 9y ago
"hit piece by big Pharma" seems a bit overstated. It has the same lack of nuance that an accusation by drug companies often make against AMA as a cartel in defending drug pricing. There are examples of gross abuses and genuine val
337.
by vibrio 9y ago
this is not a new problem and I'm glad to see structured analysis and thinking about it, especially in an era where technology for the characterization of cell lines (or mixtures thereof?) should be relatively cheap and easy.
338.
by vibrio 9y ago
I don't know that hipsters is the correct classification of the target crowd, it seems to be right for a population of vapid folk with abundant discretionary cash that see hedonism as an achievement. (--hey you kids, get off my lawn).
339.
by vibrio 9y ago
Isn't the point that this a Google problem? If just because Google says it is news it becomes news we are in trouble.
340.
by vibrio 9y ago
username checks out.
341.
by vibrio 9y ago
There is am ecosystem of many types viruses in all of us, healthy or not. Part of that ecosystem is HERVs or Human Endogenous Retroviruses (PERVs are the same in pigs--im not kidding). Understanding how they do or don't cause disease i
342.
by vibrio 9y ago
"local' anticancer treatment is achievable but not really effective. the promise in the CAR-T is persistence of the cells and systemic distribution so they can surveil for micro metastases and minimal residual disease, hopefully e
343.
by vibrio 9y ago
"The golden rule of investing -- regardless of asset -- remains not using more than you can afford to lose." I agree with this point, but it is also important to distinguish investing from speculation/gambling.
344.
by vibrio 10y ago
Agreed that there is a spectrum of second amendment supporters even amongst my acquaintances. "What should be do about Snowden?"is a conversation that can be fun to start over beers with mixed company.
345.
by vibrio 10y ago
I completely agree with your sentiment, but privacy is a bit harder to sell--guns are badass and cool to collect, privacy is geeky and suspicious. Another key difference is that the second amendment is big business (Smith Ruger & co st
346.
by vibrio 10y ago
agreed. sort of my point: some changes can be beneficial, but the process is very risky and the cell goes through great measures to minimize any sequence changes. some viruses are sloppy on purpose, as they have tens or hundreds of thousand
347.
by vibrio 10y ago
You could get a 'super T cell' that behaves just as you want, or as is empirically observed, mutations would more commonly lead to leukemia. There is a phenomenon call somatic hypermuatation, that as T-cell respond to antigens, t
348.
by vibrio 10y ago
The physiology/fundamental biology is the area that needs /deserves the academic praise and where the public support and attention will do the most good. The application of that information by Pharmaceutical companies and physicia
349.
by vibrio 10y ago
I agree resistance will develop, but i can't imagine unintended and nasty consequences. Anti-microbial peptides already exist in nature.
350.
by vibrio 10y ago
They will develop resistance, but that is not a reason to not do it. I fully agree with you that reckless antibiotic use is the core problem, but public health solutions are slow and not sexy. It reminds me that Everyone wants a pill to tr
351.
by vibrio 10y ago
a wise board member once said "Congratulations, on [good Product launch]. The optimists in your team were right. But you should remember, it's clear that the pessimists on the team are the ones that made it so."
352.
by vibrio 10y ago
I agree that medical research is broken in many ways. A steady stream of 'outsiders' set out to shake it up, from hedge fund billionaires that discover their kid has an incurable disease to google's calico grabbing some of th
353.
by vibrio 10y ago
I agree, but also think one has to consider the mode of action of the poison and the evolution of mechanisms of resistance to it. All poisons are not equal. Sure, generating some level of bleach tolerance is possible--studies using it as a
354.
by vibrio 10y ago
Well done on the deer analogy- I'm in over my head there. I appreciate and agree with your point, and think my original response was glib and not clear. Clearly, extremophilic archea have evolved to inhabit nearly every niche of the e
355.
by vibrio 10y ago
This concept is key. Growth in the presence of antibiotic in pure culture on agarose plates does not necessarily equal pathogenic potential. Every adaptation probably has a cost to the bacteria, and if you throw in the immune system and oth
356.
by vibrio 10y ago
I'm not sure bleach would be that interesting. It's like asking deer to evolve resistance to hunters' rifle bullets--it's too steep an evolutionary step.
357.
by vibrio 10y ago
Some would say the US has two grids and Texas had one.
358.
by vibrio 10y ago
Today I learned that my dog is doing her part to improve National Security.
359.
by vibrio 10y ago
There haves been increasing regulatory scrutiny given to the prophylactic use of antibiotic in animals (perhaps later than would have been optimal) http://www.fda.gov/AnimalVeterinary/GuidanceComplianceEnforc... Some o
360.
by vibrio 10y ago
sure. did you get your flu vaccine last year? will you get another next year, and the year after? You should, but there is a limit to the number of the vaccines that are feasible either scientifically, clinically, or economically.

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