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vibrio
searching PlanetScale…
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1.
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by
vibrio
7d ago
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by
vibrio
8d ago
..or a crappy casino. (further precedents)
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by
vibrio
8d ago
Circling the wagons and tending our own garden is a nice ideal, but is no panacea just because we build some factories in Cleveland, celebrate the end of Globalism , claim ‘US energy independence’ (that’s gotten quiet lately.) reassessing
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by
vibrio
9d ago
What you say is all true. Put down that book and take a trip to a Corpus Christi Texas city council meeting (eg), and help get all that silly confusion sorted out.
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by
vibrio
9d ago
Doh! (Switches on vpn)
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by
vibrio
9d ago
I wish this was just an anecdote rather than an axiom.
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by
vibrio
12d ago
Moon? I’m starting to wonder if there’s enough water for cities on earth.
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by
vibrio
13d ago
Batttlezone was the tank game.
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by
vibrio
17d ago
What are their data privacy and security policies? That is an important consideration.
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by
vibrio
1mo ago
…and a trusted doctor isn’t necessarily a replacement for the CDC.
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by
vibrio
2mo ago
Nice work! Love it.
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by
vibrio
2mo ago
Wtf world do we live in that this sentence exists.
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by
vibrio
2mo ago
To add a somewhat cynical view, a significant part of the original motivation for the ranibizumab (Lucentis) development was due to pricing arbitrage across diseases. bevicizumab was priced based on uses in cancer indications with a “large
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by
vibrio
2mo ago
I agree with you that AAV is clearly a useful tool but at times the low levels of self discipline and scientific rigor that the field has applied to dosing is disappointing at best and scary at times. This includes use of other vector types
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vibrio
3mo ago
I suspect there is a deep sequencing service that is non CLIA and cheap. True. they may not be trustworthy with the data. That said, there are steps here where the data is put into Claude. Do we trust that ?
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by
vibrio
4mo ago
Maybe also an interesting case study in the inconsistent application of copyright law.
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by
vibrio
4mo ago
I think their point is not the ESG component, but firms with traditionally irrational valuations (à la GameStop) for which index inclusion exceptions have been made to facilitate short term liquidity for IPO participants. Seems as though o
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by
vibrio
4mo ago
I can’t wait until Thanksgiving.
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by
vibrio
5mo ago
Just in that it’s not gonna work.
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by
vibrio
6mo ago
…Better plan all day Better plan all week, better plan all month, better plan all year…. (Sorry, esoteric song lyric that applies.)
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by
vibrio
7mo ago
Interesting analogy.
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by
vibrio
7mo ago
This is interesting. As a naive user I’ve gotten the gut feeling of commoditization among the models. I assumed the data center capacity push is intended to be the differentiator but that still seems utility-like over time. (and the data
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by
vibrio
7mo ago
(not intending ot be snarky, but this isn't my area of knowledge in the least.) Didn't the AI organizations 'get it both ways' when they trained on vast collection of works under copyright and then purely "own'
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by
vibrio
7mo ago
You've succinctly identified and communicated a real problem. In your opinion, what is the best approach, if any, to attempt to address it?
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by
vibrio
8mo ago
Put this way, this seems reasonable. Beyond cell therapy, I don't thin the cost of drug is the motivation for not making it more freely available. 'Misuse' leading to potential liability or unjustified bad outcomes, along wi
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by
vibrio
8mo ago
So charging patients/insurance companies at cost to fund the clinical studies?
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by
vibrio
8mo ago
Not even cost plus? Not sure how that works, from the viewpoint of economic incentives.
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by
vibrio
8mo ago
Knowing whether drugs work isn’t trivial. Patients are typically very heterogeneous in their responses to drugs. For example, pembrolizumab (the most successful cancer drug ever) typically only works in, say 30% of patients depending of th
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by
vibrio
8mo ago
Cane you provide a list of the “stupid” drug approvals?
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by
vibrio
9mo ago
lol. The battery life seems so short, I was starting to wonder whether this was the case...
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