Y
HN Search
Hacker News Search
new
|
comments
|
top
|
jobs
varelse
searching PlanetScale…
1.
▲
2.
▲
3.
▲
4.
▲
5.
▲
6.
▲
156 ms
·
901.
▲
by
varelse
13y ago
But as in all things, Anton makes a controversial set of assumptions and approximations w/r to long-range electrostatics so it's anyone's guess whether their approach is valid or not. All that aside, Anton is a wicked cool pi
902.
▲
by
varelse
13y ago
Actually, Vijay Pande's lab has been "folding" proteins in hours to days for years now by massively parallelizing the trajectories: http://en.wikipedia.org/wiki/Markov_chain_Monte_Carlo Similarly, David
903.
▲
by
varelse
13y ago
They are. But the previous generation of scientists came of age when Molecular Dynamics was a disappointing tool because of limitations in the Newtonian models and the lack of computational firepower to do sufficient sampling. The latter h
904.
▲
by
varelse
13y ago
OTOH you can't get sufficient sampling on anything but the smallest systems to make any sort of dynamic prediction about it. Not to mention the approximations that were made during the choice of basis sets for the atomic orbitals and
905.
▲
by
varelse
13y ago
Why no Harold Scheraga? Seriously...
906.
▲
by
varelse
13y ago
In my solipsistic personal and 100% anecdotal experience, making room for something philosophically 90+ degrees away from your day job is a learnable skill. I've frequently coped with ghastly day jobs (including my brief stint at Goog
907.
▲
by
varelse
13y ago
Housework isn't cardio, but it burns plenty of calories. I've measured it. And who needs to exercise outdoors? You can frickin' walk up and down stairs if you have to. It's a question of priorities. I work exercise in
908.
▲
by
varelse
13y ago
Confused? Not at all. I personally watch really godawful action movies on my spin bike on a regular basis. And if you're on your feet all day, by all means, eat what you want, you're going to need it! But don't lump yours
909.
▲
by
varelse
13y ago
And I think that's because they've convinced themselves that things are never going to get any better. They're completely and utterly wrong about that. But to get there would involve taking a new approach to getting out of w
910.
▲
by
varelse
13y ago
At the risk of losing some of the karma I've built up every time I deconstruct Google's hiring practices, here goes: High Fructose corn syrup and subsidizing horrible nutritional choices is at least partially to blame for the obes
911.
▲
by
varelse
13y ago
Purple Wage anyone? http://en.wikipedia.org/wiki/Riders_of_the_Purple_Wage
912.
▲
by
varelse
13y ago
And that's exactly what happened to me. I was senior level talent at the preceding employer with a fantastic track record. When I started at Google, I was effectively told to start over from scratch. I'm not just in it for the
913.
▲
by
varelse
13y ago
I had an offer for something more suited to my skills before I left Google, skills that I knew Google would ultimately need, but didn't yet need when I was there. In fact I had previously turned said offer down to join Google in the f
914.
▲
by
varelse
13y ago
As one of the vocal ones(tm), even I would say Google is fantastic if you get allocated onto the right team. This obviously occurs most of the time or the place would be out of business. What led to me becoming one of the vocal ones is wha
915.
▲
by
varelse
13y ago
Google has both offices and cubes arranged around collaborative groups of 4-6 workers. It's not an open floor plan, but it's not individual cubes either.
916.
▲
by
varelse
13y ago
It's all fun and games until your programmer starts vomiting...
917.
▲
by
varelse
13y ago
Yours is an honest mistake. Just don't do it again. Or at least consider breaking it up into separate collaborative groups. My personal experiences with open offices have all been at large organizations bending over backwards to expl
918.
▲
by
varelse
13y ago
I gotta say it - those 160 column printouts of code were awesome for debugging over a cup of coffee... And they still are. When you can look at 500+ lines of code at once spread over a table, you can immediately see all sorts of things t
919.
▲
by
varelse
13y ago
My favorite past employer had a sea of 8x8 cubes. The solution to communications issues like this was all you can eat Friday night pizza parties. People stayed to 11 PM hashing over issues of the week. One day, the beancounters decided t
920.
▲
by
varelse
13y ago
Open offices are a line-item cost cutting measure and nothing more than that. While they destroy the ability to write code and ergo engineering productivity, they are providing important data on the minimal environment from which productiv
921.
▲
by
varelse
13y ago
And that's just it, Patrick is mostly a perma-bear. So trotting out his recommendations when the market is stupid up makes him seem more sagely than I personally think he is. When I used to participate in his online forum, it seemed to
922.
▲
by
varelse
13y ago
This looks like the same set of points Patrick has been making since before the bubble burst. They're all great rules of thumb. And all bubbles pop eventually, but the problem is that it's very hard to predict exactly what pops
923.
▲
by
varelse
13y ago
If you work on a team, mark time on your calendar where you are busy and stick to it - there are very few emergencies that really are more important than maintaining your own personal productivity - in the rare event that you hit one, thr
924.
▲
by
varelse
13y ago
A long time ago my very athletic college girlfriend dumped me for a very athletic version of me. In the final weeks of that doomed relationship, I desperately hit the gym to try to stop the inevitable end of that first love. I failed. But
925.
▲
by
varelse
13y ago
People are unwittingly bearing the cost of this in terms of ridiculously low interest rates on savings and high unemployment.
926.
▲
by
varelse
13y ago
In the western world, gain is privatized, and loss is socialized. Nothing changes unless tax rates or some other form of revenue emerges to back up that socialization. Oh wait, my money market account is earning ~0.15%. Silly me, problem
927.
▲
by
varelse
13y ago
More proof that everything comes in threes. Just like the Ramans...
928.
▲
by
varelse
13y ago
Just like there was a relatively cheap countermeasure to every pipe dream revision of the SDI, such countermeasures are already in place for facial recognition: http://news.discovery.com/tech/gear-and-gadgets/glass
929.
▲
by
varelse
13y ago
It could certainly narrow the field. Combine a vector of "features" derived from the single image that with a bunch of other orthogonal "features" such as location and I could see it improving efficiency of manhunts sig
930.
▲
by
varelse
13y ago
Given the 15.8% success rate of the cat detector on large data sets: http://arxiv.org/pdf/1112.6209.pdf&embedded=true , My chief worry is overconfidence from hopelessly technologically ignorant bureaucrats combined
More ›