smallgovt

9 ms·

31.
by smallgovt 6y ago
Tl dr; Moderna vaccine exits Phase 1 trials successfully. "Clinical development is a three-phase process. During Phase I, small groups of people receive the trial vaccine. In Phase II, the clinical study is expanded and vaccine is give
32.
Moderna says COVID vaccine trial produced robust immune response in all patients(cnbc.com)
9 points by smallgovt 6y ago|6 comments
33.
by smallgovt 6y ago
Interesting theory. Is there a way to quantify how evenly investing, say $200B, across the S&P would affect the index's price?
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by smallgovt 6y ago
>> The bots didn't identify as FB (used "spoofed" UAs) That's surprising. What were the spoofed user agents that they used? We've run into this issue also, but all Facebook bot activity had user agents that c
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by smallgovt 6y ago
The fact that many investors will outright dismiss Skilling based on his track record is exactly what would attract amoral investors. One man's trash is another man's treasure.
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by smallgovt 6y ago
How do we support non-profit sites like this more? I think it's pretty absurd that Grubhub and Uber take such a large commission for what amounts to pretty basic software. But, I bet this site isn't getting much traction because i
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by smallgovt 6y ago
How is this random? Uber has been making significant investments in the food delivery space via their Uber Eats offering. Consolidation makes sense given industry-wide razor thin margins and intense competition.
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by smallgovt 6y ago
Grubhub actually only charges 10% for delivery. It charges an additional 15%+ for the marketing component (to get your restaurant listed and to appear higher up in search rankings). In other words, if a restaurant sources their own customer
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by smallgovt 6y ago
Source?
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by smallgovt 6y ago
There's a guy that's working on an app that helps you order directly from local restaurants so they can save on commission fees: https://www.eatnyc.org/ I think the app only covers NYC for now.
41.
by smallgovt 6y ago
You may be right, but my thought was that people can't go back to work if their kids are stuck at home.
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Sweden didn't shut down. Hospitals are not overwhelmed. Cases have plateaued(bbc.com)
26 points by smallgovt 6y ago|31 comments
43.
by smallgovt 6y ago
What is your reaction to Sweden's COVID track? They didn't shut down daily life, and their hospitals are doing just fine. In fact, COVID cases and deaths have plateaued. Source: https://www.bbc.com/news/world
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by smallgovt 6y ago
> Blanket lockdown has to end. I tend to agree. Why is nobody focusing on Sweden's COVID numbers? Sweden didn't institute city-wide shutdown measures. Yet, there hospitals are not overwhelmed. And, their COVID case counts an
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by smallgovt 6y ago
Um, I'm not sure if you're being serious, but there are plenty of ways to gradually re-open. As an example: step 1) re-open elementary schools step 2) re-open middle schools step 3) re-open high schools & colleges step 4) re-
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by smallgovt 6y ago
To be fair, the cost of COVID medical care pales in comparison to the likely impact on future earnings these shutdowns are having. If it's strictly about money, we should cease shutdowns immediately. But, it's not. People are dy
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by smallgovt 6y ago
> How is it moral to order people to shelter in place when their risk of death is 0.01% for 18-45 year olds The data from your second source indicates that the case fatality rate in New York for 18-45 yr olds is 0.833% (14 deaths in 1705
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by smallgovt 6y ago
If you were doubting that the +3% market movement was primarily driven by this news, take a look at the markets at 12:40PM today when negative news of clinical trials for the drug were released. Again, direct minute by minute correlation b
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by smallgovt 6y ago
I think you've outlined an excellent framework/technique to self improvement -- not dissimilar to the Carol Dweck's 'Growth Mindset'. However, I think it's very likely GP has a much more pernicious problem. Th
50.
by smallgovt 6y ago
Stock futures are up 3% on this news so there appears to be something to this.
51.
by smallgovt 6y ago
> If founders say something along the lines of YC decides after term sheet, it basically means no. Why would it basically mean no? It seems like the new policy makes the answer "Maybe, and there's no way to find out until a le
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by smallgovt 6y ago
Ah, I see. Is it true that these tests are a work in progress and the false positive rate will drop in the coming weeks/months? If so, it seems like we should start doing random sampling and saving the samples for future testing (so w
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by smallgovt 6y ago
This published scientific article shows you why the CFR in Italy is so high -- and why it doesn't apply to the general population: http://jamanetwork.com/journals/jama/fullarticle/2763667 Takeaways: Old
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by smallgovt 6y ago
Does this study change your mind on that 20-30% figure? After all, the study measured a 35% infection rate for people living in close quarters with other infected individuals. Surely, the overall population would yield a much lower infect
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by smallgovt 6y ago
> We can't say for certain that the sample is an exact representation of the general population. I actually think we can say for certain this is NOT a good representation of the general population. The general population has not be
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by smallgovt 6y ago
> We need more studies to gather data on these asymptomatic cases if we want to reopen the economy soon. I don't understand what's so hard about measuring population infection rate. Assuming the population infection rate is bet
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by smallgovt 7y ago
Simply put, no. No evidence other than hearsay. And this, after countless lawsuits.
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by smallgovt 7y ago
I would hardly call them credible reports. It's easy to see how business owners could draw false inferences when they receive a Yelp sales call and coincidentally get a negative review shortly after. Honestly, I thought this was long
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by smallgovt 7y ago
> You’ve moved the goalposts here though. You first argued how none of these small business owners brought forward evidence and therefore this isn’t a real scandal. I never moved the goalpost. My claim has always been that there is zero
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by smallgovt 7y ago
Obviously the number one existential threat is different for each startup. He's simply saying that lack of runway is the most likely cause of death now. Most industries will probably return to normal in 2-3 years time.

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