searine

26 ms·

271.
by searine 7y ago
Opioids work wonders for chronic pain, the downside being obvious, but when used responsibly they are a lifesaver. Lurk any chronic pain support group and you will find hundreds of people terrified of going back to the dark ages before opio
272.
by searine 7y ago
>there already is a cure to chronic pain and it is called correct diagnosis. There are many many conditions where even with a proper diagnosis there is little help. One of the easiest things to do with chronic pain patients is to minimiz
273.
by searine 7y ago
I don't think I'll ever forgive the environmental movement for turning their back on nuclear technology. Yes, there are safety concerns but the price of inaction was the climate. I would take an accident or two over climate change
274.
by searine 7y ago
I wouldn't be surprised if the Volt comes back in a few years as a full EV sedan.
275.
by searine 7y ago
>Some people are not interested in those pursuits and they are, in comparison, very "pedestrian" in terms of complexity. Now I enjoy all things related to food for example, but I would stab myself in the ears if I had to talk t
276.
by searine 7y ago
That is the single main state route into Hanover. So that sign is highly visible actually. I would be more appropriate on campus but the building that housed the computers no longer exists. The library where the terminals were is still ther
277.
by searine 7y ago
It's not just writing. Being around a group of highly-skilled peers sets the bar. It exposed your shortcomings and gives you a resource to remedy them.
278.
by searine 7y ago
>The Department of Defense's own DNA database (DoDSR) The reality of this is that it's just a big ass warehouse deep in the farmland of Virginia which houses unprocessed tubes of DNA. Its like the end of Raiders of the Lost Ark
279.
by searine 7y ago
"Mom's Across America" is a well known science denying hotbed who stoke fear of GMOs, chemicals, and vaccines. They don't care whether or not glyphosate is safe or not. They care that impossible foods is getting headline
280.
by searine 7y ago
>You don't think you're mixing up "heritable" with "genetic" here? "Heritable" in this context is a term of art. It is a statistic (H squared) that describes the amount of a phenotype that is trans
281.
by searine 7y ago
>Statistics. Garbage in, garbage out. The problem isn't the statistics, and it isn't the solution either. Its the diagnosis data. How do you quantify if someone is depressed? How depressed are they? How do you compare two peopl
282.
by searine 7y ago
>It's just naive to pin something as complex as depression No it's not. Twin-based heritability studies show depression risk has about 10% heritability across all cases and 50% heritability among severe cases. There is a geneti
283.
by searine 7y ago
As someone who works on depression GWAS, this isn't the end of finding causal genes for depression, it's the beginning. In the next few years we're going to see a waterfall of new rare variants linked to disease, all which ha
284.
by searine 7y ago
>I was taught a decade ago that rolling your own in genomics isn't as bad of a decision as it seems. Famous last words.
285.
by searine 7y ago
[Hello my name is Peter Barakan Intensifies]
286.
by searine 7y ago
>it completely misses the point of what made Timex famous to begin with; excellent quality at a low price. Brands change, particularly fashion brands. Many high-end brands become debased and low end brands slowly scale up in quality to b
287.
by searine 8y ago
Excluding risk variants, they are FDA approved to test : BRCA1 BRCA2 Alpha-1 Antitrypsin Deficiency G6PD Deficiency Hereditary Amyloidosis (TTR-Related) Hereditary Hemochromatosis (HFE‑Related) Hereditary Thrombophilia Late-Onset Alzheimer&
288.
by searine 8y ago
Associations form the foundation for future reportable SNPs. Many of their tests are now FDA approved. Many of the variants they report have clear and drastic impacts on health. You are splitting hairs to be bitter.
289.
by searine 8y ago
> Such SNP chips are currently used in exactly zero real world (human) medical applications. That's not true at all. There have been dozens of publications using that data and they have been instrumental in progressing our knowledge
290.
by searine 8y ago
I've been following TEPCOs media site casually for years. They actually used to have a really great media site showing the latest work being done on decommissioning but its gotten more and more closed off over the years as people care
291.
by searine 8y ago
Like your face or fingerprints, DNA is just going to be one of those immutable features of identification.
292.
by searine 8y ago
Seconded, amazing book, wish it was longer!
293.
by searine 8y ago
Try google scholar next time instead of regular google search.
294.
by searine 8y ago
>Because if meta-studies only get to include the single most recent and largest study, they wouldn’t be very ‚meta‘, would they? I'm saying the earlier are clearly non-specific to glyphosate. The 2015 and 2018 AHS are targeted to gl
295.
by searine 8y ago
Thoughts as I read: This is a review, not original research. It seems to also conduct a meta-analysis as part of this, however that is somewhat unusual for a review. In general, both the review and meta-analysis quality is dependent on the
296.
by searine 8y ago
Not all jobs are equal. Are the jobs we are adding good ones? or desperate ones?
297.
by searine 8y ago
Play stupid games, win stupid prizes.
298.
by searine 8y ago
They might be two different issues. General insect collapse is likely dude to the overuse of broad spectrum insecticides. Monarch collapse is more likely due to reductions in milkweed population. Milkweed is often found on the edges of corn
299.
by searine 8y ago
"Matching" in dating apps is old world thinking. "Swiping" has largely replaced computational matching because it outsources the decision to the user and allows for high-through-put decision making. Users set a radius an
300.
by searine 8y ago
I'd love to use this as a meat-replacement but can ordinary consumers buy it yet? I just want to make chili. Please let me give you money!

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