new299

21 ms·

151.
by new299 6y ago
I assume by “works” you mean in relation to COVID19? Sars-Cov2 is a respiratory disease. I guess it maybe present in blood, but it doesn’t seem like removing it from blood would help with the respiratory issues it causes. I can’t see how yo
152.
by new299 6y ago
All phases will be testing for safety to varying degrees. So... a challenge trial at phase III will still have risks. Right now, I don’t think we have any vaccines ready to enter phase III? COVID19 does seem to be actively spreading in the
153.
by new299 6y ago
You, and the vox article, seem to assume that the risks are all associated with COVID19 in the trial as similar to those normally associated with COVID19 in the human population.. One of the issues with vaccine development is that vaccines
154.
by new299 6y ago
When they were released in the 1990s they were pretty capable machines. The OS had its issues, but I don’t think it faired badly against DOS/Windows 3.11. They were however largely limited to the UK marketed, and had a more limited sel
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by new299 6y ago
The irony is that the ARM architecture was also developed in the same way. A custom CPU, for a new machine, with an operating system specifically designed for it, and applications written specifically for that OS (the Acorn Archimedes/
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by new299 6y ago
There was a post on the front page a few days ago suggesting than a naturally attenuated form of SARS-CoV-2 should be found. This preprint linking mutations to pathogenicity may be of interest.
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Patient-derived mutations impact pathogenicity of SARS-CoV-2(medrxiv.org)
3 points by new299 6y ago|1 comments
158.
by new299 7y ago
> SARS-CoV-2 RNA was identified on a variety of surfaces in cabins of both symptomatic and asymptomatic infected passengers up to 17 days after cabins Unless there’s more to this, it doesn’t seem very useful to me. It seems obvious to me
159.
by new299 7y ago
But you do seem to be suggesting that "people spreading it around on their own" is a "solution to Covid-19"? Otherwise, what is your plan for this attenuated strain? Don't get me wrong, I think large scale sequencin
160.
by new299 7y ago
Perhaps I’ve missed something in your argument then. I’d need to understand exactly how you are planning to promote the spread of the attenuated form. If you’re talking about a “sequencing driven” Pox party [1] then I suspect you will run i
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by new299 7y ago
> What are regulatory agencies going to to do? If you were to start doing this without regulatory approval, the most likely outcomes seems that you’d be arrested [1]. Do you have anything that suggests otherwise? > 1. We would know it
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by new299 7y ago
You make this statement: "The most important thing to note is that such a virus would not be a vaccine from a regulatory perspective." Can you provide any evidence to back up this statement? If you were to start intentionally infe
163.
by new299 7y ago
> I’ve been employed there a few years > I really just want to go and do something else It sounds to me like you’ve already decided. It might be time for a change anyway? If you have some equity (and don’t gave terms that make it diff
164.
by new299 7y ago
The website states “no-human-in-the-loop”. So I guess it depends on how much you trust them. It seems like all component positions need to be fixed first, then it routes between them. That’s based on the examples, fact that it takes DSN inp
165.
by new299 7y ago
From what I can tell, you need to position all the components and then it routes between them...
166.
by new299 7y ago
The website says there’s no human in the loop... but who knows. It takes dsn input files and outputs ses files (if the examples are accurate). The ses files appear to contain traces only. So I assume you would import these over your already
167.
by new299 7y ago
I would imagine that it’s not the suns location that is the primary concern, but where you are directing the light. The light is being reflected and focused by mirrors. That light is being directly onto some volume of material. So, in this
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by new299 7y ago
Bill Gross, Heliogen’s current CEO previously founded eSolar. eSolar proposed using an array of Heliostaticly controlled mirrors to direct light toward a solar cell: https://en.wikipedia.org/wiki/ESolar So... that part
169.
by new299 7y ago
A number of companies are working on cfDNA (cell free DNA) approaches to early cancer detection. GRAIL and Freenome are probably notable examples. Far fewer seem to be looking at miRNA, as Toshiba are here. I know of one other in Japan with
170.
by new299 7y ago
Bill Gross, Heliogen’s current CEO previously founded eSolar. eSolar proposed using an array of Heliostaticly controlled mirrors to direct light toward a solar cell: https://en.wikipedia.org/wiki/ESolar So... I’d guess
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by new299 7y ago
The audible audiobook version of Anathem is extremely good in my opinion. Probably one of my favorite readings... I’m surprised that speech synthesis does a reasonable job given the language involved.
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by new299 7y ago
The delivery method is generally the missing piece. For the first of the reports mentioned here the authors used bacterial conjugation [1] as the delivery method. They note that: "In culture conditions that enhance cell-to-cell contac
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by new299 7y ago
Well what bunnie says in that talk is that something may well have happened but it doesn’t pass Occam’s razor as presented in the Bloomberg article. Specifically he says that adding an IC to the board doesn’t make sense. And that embedding
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by new299 7y ago
I think the fact that fake components regularly make their way into the supply chain should be more of a concern than the supermicro story. So, supply chain security is poor, and getting backdoored parts into the supply chain is a realistic
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by new299 7y ago
Right, so I’m not sure what the purpose of the cost estimate is. To show you don’t need expensive tools? If that’s the case, then 200USD is massive over-estimate. You only need a soldering iron, and the parts. If you’re looking at the time
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by new299 7y ago
You can do this with a 30USD soldering iron by eye. None of the other equipment is essential.
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by new299 7y ago
This seems not terribly interesting to me. The article motivates itself the allegations of devices embedded in supermicro products saying “But even as the facts of that story remain unconfirmed...”. But it’s not that the facts as unconfirme
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by new299 7y ago
This is a nature news feature, not a scientific publication. The later still “means something” if you care about that sort of thing.
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by new299 7y ago
I guess 3nm is just marketing, but I’d be interested in better understanding the feature sizes here and in current processes. From what I can tell, in their current 5nm process the smallest features are on the order of 30nm? Is that correct
180.
by new299 7y ago
> just for the purpose of extending their patent I don’t understand this point, though I’ve heard it before. If the original patents expire, the original drugs can be manufactured as generics right? If the new patents provide no new bene

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