glp1guide

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by glp1guide 2y ago
Yup this is true -- it's common for very rapid weight loss to produce those same effects. Maybe if they'd done it much more progressively (i.e. picked a less effective treatment method) then they might not have the Ozempic Face,
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by glp1guide 2y ago
Well, that's swung the other way very quick -- that's a pretty callous way to look at it IMO but to each their own. Glad these drugs exist and are an option for people struggling with obesity though.
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by glp1guide 2y ago
> After the fast is over, I switch back to normal meals and weight lifting. "weight lifting" is doing a lot of lifting here probably. Strength training and building muscle is so beneficial for weight loss/body building in
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by glp1guide 2y ago
I know this is a joke, but you know what, it's actually kind of true now. There are absolutely downsides to GLP1 drugs, but the way they work is well-studied, and with a low enough price and high enough availability (and a lot of luck
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by glp1guide 2y ago
Funny way to spell GLP1 Receptor Agonist but "Ozempic Relative" works too
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by glp1guide 2y ago
Note that GLP1 receptor agonists are a whole class of drugs, and they were known to be effective in treating diabetes as well, and have been for a while. Recent commercialization and buzz is definitely new and there have been new formulatio
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by glp1guide 2y ago
Yeah it'd be really great if these kids didn't become this obese in the first place, but the anecdote in the article is a very specific case: > So Grace fought to get her middle-schooler on the new obesity drugs. Because no ped
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Show HN: A F/OSS listing of GLP1 related resources(github.com)
1 points by glp1guide 3y ago|0 comments
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by glp1guide 3y ago
Just to add to this, there's data to support the intuition there that there is long term good in taking GLP1s even after you stop: https://glp1.guide/content/do-people-regain-all-the-weight-l... Now, we need price
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by glp1guide 3y ago
> As an aside, also getting on a dose of Semaglutide has been similarly life changing. The damn near elimination of "food noise" has been incredible. >. I know there are a number of folks of the opinion that its somehow chea
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by glp1guide 3y ago
Sorry VERY late here (I somehow missed this), but have you considered weight training? From an efficiency point of view it seems hard to beat. Building muscle (like you'd like to) helps with metabolism, etc. Of course cardio with a con
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by glp1guide 3y ago
Thank you it's really nice to hear (read) someone say that!
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by glp1guide 3y ago
We are still early in the evolution of the GLP-1 Receptor Agonist class of drugs. Always great to look ahead though -- and most of these drugs work in similar way, i.e. they are GLP1 + something else. I personally think we're going t
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by glp1guide 3y ago
> Side note, GLP1 based therapies are being investigated for improving brain health and potentially helping prevent the development of neurodegenerative illnesses, potentially because of an anti inflammatory feedback mechanism it activat
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by glp1guide 3y ago
> I was skeptical about last year's glowing articles about Ozempic and other GLP-1 medications. Like so many chronically overweight people, I'd seen it all and then some: stimulants, supplements, low-carb, low-fat, intermittent
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by glp1guide 3y ago
> The drug amycretin caused people to lose 13 percent of their body weight over three months, according to the results of a phase one trial announced by the company. No mention of the risks and side effects, but those are some staggering
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by glp1guide 3y ago
Eli Lilly has made a lot of fuss about it's direct to consumer service, but IIRC it was basically an online prescription farm and a bit less... direct to consumer. That said, great to have these drugs be more available period -- manu
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by glp1guide 3y ago
I think this is one of the reasons that Rybelsus will do really well. It ends up being quite a low dose because of how much of it is lost in the ingestion process, but a pill is certainly much easier. > Chronic GI issues are definitely s
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by glp1guide 3y ago
> I used saxenda, and now mounjaro - I've always struggled with food noise and I don't think many non obese people are aware of how life consuming this is. Any reason you moved between these in particular? Victoza/Saxenda
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by glp1guide 3y ago
I am extremely biased, but I have to say... This is the way. I do want to note that GLP1s are not miracle cures for insatiable hunger, they don't necessarily work for everyone and may (rarely) have side effects that aren't worth b
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by glp1guide 3y ago
> Its changed my life. Never went to the gym once. Ate whatever I wanted. Simply didn’t want much to eat. This is really powerful. I think most people are going to want to pair going to the gym with it (hedonic treadmill and all that), b
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by glp1guide 3y ago
I don't think it needs to go that far -- one of the effects of capitalism is indeed competition-induced reduction of prices. Pharma is a bit different, but with time prices should go down and availability should go up. Also note that t
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by glp1guide 3y ago
Were you on Rybelsus? I think that one has one of the biggest potentials to be really widespread in use. It's a low dosage (which looks high just because you lose so much of it in your body) -- pills are easy to take. The costs are ve
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by glp1guide 3y ago
GLP1 Receptor Agonists[0] are going to change a LOT of things going forward. If we're having problems with price & accessibility now, I hope that gets solved before some of this stuff goes full swing. That said, Wegovy is made by N
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by glp1guide 3y ago
So note that although Semaglutide/Ozempic cost that amount retail, most are absolutely not paying that price. https://glp1.guide/content/glp1-pricing-2024-02 Of course, insurers are struggling to not cover the bil
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by glp1guide 3y ago
Also, possibly curing cancer: https://glp1.guide/content/glp1-vs-cancer
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by glp1guide 3y ago
Ozempic is definitely not just propaganda -- there's good research and outcomes to back it's effects. There HAVE been some questions as to how it works (and that the traditional understanding might be wrong), but...
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by glp1guide 3y ago
Note that insurers are already trying very hard to NOT cover Ozempic and other drugs[0]. While medicaid accepted the drugs federally, it's up to states to control how they support the drugs on their plans, and the cost of them seems
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by glp1guide 3y ago
Wow this is a fascinating thesis -- GLP1 was known to affect the stomach AND the brain, and it certainly does affect the stomach, but for the weight loss properties to be simply brain-driven might be a bit simplistic. It certainly does ex
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GLP1 Receptor Agonists vs. Cancer(glp1.guide)
2 points by glp1guide 3y ago|0 comments

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