3 ms·

I think this is one of the reasons that Rybelsus will do really well. It ends up being quite a low dose because of how much of it is lost in the ingestion proce

I think this is one of the reasons that Rybelsus will do really well. It ends up being quite a low dose because of how much of it is lost in the ingestion process, but a pill is certainly much easier. > Chronic GI issues are definitely something that should be avoided and I think lower dosing helps with that. This simple/obvious take is really quite often left out of the common objections to the drug on side-effect grounds. I wasn't sure it was necessarily true but it certainly makes intuitive sense -- if you're having a strong reaction, take a lower dose and plan your weight loss around that.

cjbgkagh 3y ago
Yeah, quite a lot is lost via oral, I do worry with the dosing being uncertain with different stomach conditions resulting in different effective doses. Due to the cost savings I'll stick with injecting but totally understand that most people are adverse to that. Permanent gastroparesis is nightmare fuel and I worry about people assuming ozempic a safe drug and being cavalier with the higher doses. There is a risk/trust dynamic between doctors and patients where doctors want to keep doses on the 'known path' and patients trust their doctors a bit too much.