dekhn

5 ms·

1.
by dekhn 6d ago
There are two different "cure cancer" meanings. I meant, when somebody stops having cancer, we don't say they were cured. We say they are remission. That's because even if you completely remove all visible tumor, 20 ye
2.
by dekhn 6d ago
This is an extremely low quality and likely AI-generated article that contributes little to nothing to the ongoing progress of AI for bio.
3.
by dekhn 6d ago
Could you clarify what you are trying to achieve with this comment? I work in a related field and talk to stem cell/organoid growers from time to time. It is in fact hard to grow brain organoids from stem cells; this is still very muc
4.
by dekhn 6d ago
To me, transistors are the best example of how hard EE can be. I heard "transistor is a switch" or "transistor is an amplifier". So I bought some MOSFETs and tried to use them. No go. Well, I had to learn (through ra
5.
by dekhn 6d ago
lcamtuf is one of the smartest people I've ever seen. When you read his work you realize he's only sort of putting about 1% of his intelligence on the page.
6.
by dekhn 7d ago
Yes, I do, although I noticed that I had a hard time reading the text, the images were so interesting.
7.
by dekhn 7d ago
While the popular press does bungle nearly all cancer research findings, the last 20 years have been unbelievably productive in cancer treatment. No, we haven't and aren't going to cure cancer any time soon.
8.
by dekhn 7d ago
Mostly the parts I hear about. But I also communicate with mathematicians on a regular basis and I can see what they are working on, which is representative of the field. It's about 90% "cohomology of abstract Lie groups that mo
9.
by dekhn 7d ago
I have been losing interest in this proof-oriented approach into extremely abstract concepts (what seems to be the core of academic mathematics today). Obviously, proofs are very attractive because they are the closest thing we have to a u
10.
by dekhn 9d ago
What's an allele? There is no real answer to that question. Or rather, the concept of allele is highly abstract and does not correspond well to actual genomic sequences. Predicting phenotypes is not a linear function of the genome. I
11.
by dekhn 9d ago
Genetics is complicated enough that both things can be true without circular reasoning. I've studied genotype to phenotype mechanisms for a very long time (but from the lens of molecular biology, biochemistry, and biophysics, rather th
12.
by dekhn 10d ago
Fusion 360 can convert many STLs to BREP automatically. It can be slow and error prone but it does work. It will recognize large regularly curved areas and replace thousands of triangles with a single smooth curve.
13.
by dekhn 15d ago
Yes, I remember. See anything familiar on https://www.weeklyrobotics.com/articles/2023_01_25_the_histo...
14.
by dekhn 15d ago
With regards to Franklin and DNA: the credit went to Watson and Crick because they had the fundamental insight: that DNA is an antiparallel double helix (Franklin knew it was a helix, but not an antiparallel double helix, which is key t
15.
by dekhn 15d ago
When I worked at Google, we spent $100M in power on protein folding and drug discovery (this was long before AlphaFold). Never underestimate the willingness of smart rich people to invest in speculative science.
16.
by dekhn 15d ago
I 3D print cable rocks and mount them in my garage and then hang them in groups by type. I also get rid of every cable type I haven't used in 10 years because you can always just buy more of that cable.
17.
by dekhn 15d ago
Which ones? I have a copy of the movie and can go back and check. But in my experience nearly all the jokes had already been done in the original show, or were duplicative of jokes from other "X vs Y" movies.
18.
by dekhn 16d ago
I don't engage with hyperbole.
19.
by dekhn 16d ago
The claim that OpenAI somehow used the mathematicians' ideas to leapfrog them seems unsupported at this time and IMHO it was irresponsible to bring it up because credulous people will immediately believe that narrative. And from my per
20.
by dekhn 16d ago
rates beat counts almost always.
21.
by dekhn 16d ago
Reputational risk- if they lie about this and get caught, it will have billion dollar implications for their business.
22.
by dekhn 16d ago
Yes, it's pretty clear that's a common pattern.
23.
by dekhn 16d ago
I think pretty much every major mathematician has accepted that the ideas and implementation behind lean is solid.
24.
by dekhn 16d ago
Tell me you don't understand how cancer or medicine works, without telling me you don't understand how cancer or medicine works.
25.
by dekhn 16d ago
Didn't OpenAI make a Lean proof? https://github.com/openai/NavierStokesAndEuler/tree/main/Nav... "This repository contains Lean 4 formalizations of the results presented in “Finite time blowup
26.
by dekhn 16d ago
Individual crystal structures, while heroic, probably don't qualify for the Nobel Prize (the only counterexample that I can think of is the crystal structure of the ribosome, which finally demonstrated that the active site was RNA, not
27.
by dekhn 17d ago
I simply feel that it could have been 10X better. They had everything for it to be great, and it was just.... adequate. Here's an example of Looney Tunes elevating the genre: https://en.wikipedia.org/wiki/What%27s
28.
by dekhn 17d ago
A prior of "one large company is current involved in an unrelated lawsuit with another large company" is pretty weak; the case is undecided and about an entirely different kind of IP theft. In short I think a lot of people are jum
29.
by dekhn 17d ago
I watched it (I'm a big old school looney tunes fan) and I don't think I laughed even once in the entire movie.
30.
by dekhn 17d ago
Actually, I work in biology, which is a far more complicated and undocumented computer than any existing AI model. And we've already seen the failure models (COVID is an example).

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