NoPie

93 ms·

421.
by NoPie 5y ago
Brazzy is right and you are wrong. For big pharma to extort, first they need the product that actually works. Most gene therapy is pipe dream. There are some drugs on the market for some orphan (rare) diseases but the development is very co
422.
by NoPie 5y ago
Do we even need clinicians be able to distinguish male and female retinas? The task is meaningless. Yes, there might be some interesting facts in discovery how male and female retinas are different. It could even lead to differentiated trea
423.
by NoPie 5y ago
But for every kid like this there could be 10 austistic people with average or even above average IQ. Honestly I don't know but if autism is due to genetic differences then greater proportion will be with slight deviations from normal
424.
by NoPie 6y ago
I believe it is very possible. My android phone often asks how did I like this or that shop. Sometimes I was just passing by those shops but on average the phone is quite correct which shops I have visited. Google knows when you are in the
425.
by NoPie 6y ago
Upvote this. These events are so rare that it is hard to prove causal relationship and find the mechanism by which it happens. The rarity also means that in any case they are not very significant.
426.
by NoPie 6y ago
Sadly, I have lost more people I knew from drug overdose than from virus during last year. Most people won't care about to understand the damage that lockdowns have done to vulnerable people. The difference is that covid deaths are dir
427.
by NoPie 6y ago
There have been gains but one has to see it in the context of health life expectancy which in the UK currently is about 63 years. Modern medicine helps to extend life expectancy but often those last 10+ years are miserable clinging to life
428.
by NoPie 6y ago
You are right, that's how it was communicated by irresponsible journalists and politicians. They managed to influence the public opinion against the vaccine. Now many countries will have to deal with growing anti-vaxx sentiments and de
429.
by NoPie 6y ago
It is not how it happened at all. EMA looked at this and said – it is possible that these cases are related to vaccine but it doesn't change that the benefit overweighs risk and there was no reason to stop the vaccine. Informing patien
430.
by NoPie 6y ago
I am curious now what exactly is that puts people off when hearing from AZ? I remember there was a similar outrage when it turned out that one batch of vaccine used in clinical trials had a half-dose. It was a mistake from a contractor and
431.
by NoPie 6y ago
What exactly is your argument? Biologics are messy. It is not chemical synthesis that is easy to assay and finetune. They are growing live modified viruses. No one has made such vaccine before. Pfizer and Moderna vaccine is technologically
432.
by NoPie 6y ago
I am a pharmacist and I have followed this closely. AZ can make profits after July. They apparently did this for good PR. Unlike what people think vaccines usually do not bring much profits, so it was not a big sacrifice. The vaccine was de
433.
by NoPie 6y ago
The major fault would be ineffective vaccine or the one with bad side-effects. Or not being able to manufacture at all. They did very well, all things considered. Normally setting up such manufacturing takes years. They didn't screw up
434.
by NoPie 6y ago
I agree that AstraZeneca should have been communicating better. It is not the first time they have caused public outrage due to communication issues. On the other hand, this is pandemic and they are trying their best with the vaccine. Is it
435.
by NoPie 6y ago
Exactly, it has nothing to do with the contract. If I make an agreement to delivery 100 million vaccine doses tomorrow and then fail to do it, so what? Concentrate on real issues, on what we can or cannot do, not on some lawyers' fanta
436.
by NoPie 6y ago
The UK invested in AZ 3 months earlier. Even if contracts are not very explicit about this, it appears that AZ really saw it as a separate supply chain from the very beginning, at least for initial doses. Looking into contract is like tryin
437.
by NoPie 6y ago
I would say it is fair. The problem is the manufacturing process. The vaccine is slowly grown in large volume bioreactors. If you need long time from investment till finished product, then obviously people who invested sooner can expect tha
438.
by NoPie 6y ago
Contracts are complicated and disputed what they really mean. But it doesn't look that AstraZeneca is acting in bad faith. The UK invested 3 months sooner and that enabled AstraZeneca to solve manufacturing issues sooner. The same issu