5 ms·

What exactly is your argument? Biologics are messy. It is not chemical synthesis that is easy to assay and finetune. They are growing live modified viruses. No

by NoPie 6y ago

What exactly is your argument? Biologics are messy. It is not chemical synthesis that is easy to assay and finetune. They are growing live modified viruses. No one has made such vaccine before. Pfizer and Moderna vaccine is technologically different, and even they are having scaling issues and delays. The reason for the late notice is that most likely the issues were in the last steps of the complicated manufacturing process. Hopefully they learned from this and will be able to ramp up production.

libertine 6y ago
>The reason for the late notice is that most likely the issues were in the last steps of the complicated manufacturing process. Hopefully they learned from this and will be able to ramp up production. Watching the reaction of AZ CEO reaction, I don't see it in that light. Basically they took enough time to have EU too much compromised to turn around and look for other solutions. And don't buy the narrative that AZ isn't gaining anything from this, they're basically getting funding and facilities to enter the vaccine market. Maybe approving AZ was a mistake, and should have doubled down on Pfizer and aprove either the Russian or Chinese vaccine.
- NoPie 6y ago
  I am curious now what exactly is that puts people off when hearing from AZ? I remember there was a similar outrage when it turned out that one batch of vaccine used in clinical trials had a half-dose. It was a mistake from a contractor and they were open about it. And yet the reaction on blogosphere was as if they are some kind of frauds. AZ might not have the best PR but if they are more on geeky side I would expect HN blog to understand them even better. At least to me it seems that they know what they are doing. But I studied pharmacy and I can relate to drug manufacturing in technical details so I might not understand how a lay person sees this.

by NoPie 6y ago

libertine 6y ago

>The reason for the late notice is that most likely the issues were in the last steps of the complicated manufacturing process. Hopefully they learned from this and will be able to ramp up production. Watching the reaction of AZ CEO reaction, I don't see it in that light. Basically they took enough time to have EU too much compromised to turn around and look for other solutions. And don't buy the narrative that AZ isn't gaining anything from this, they're basically getting funding and facilities to enter the vaccine market. Maybe approving AZ was a mistake, and should have doubled down on Pfizer and aprove either the Russian or Chinese vaccine.

NoPie 6y ago
I am curious now what exactly is that puts people off when hearing from AZ? I remember there was a similar outrage when it turned out that one batch of vaccine used in clinical trials had a half-dose. It was a mistake from a contractor and they were open about it. And yet the reaction on blogosphere was as if they are some kind of frauds. AZ might not have the best PR but if they are more on geeky side I would expect HN blog to understand them even better. At least to me it seems that they know what they are doing. But I studied pharmacy and I can relate to drug manufacturing in technical details so I might not understand how a lay person sees this.