1_over_n

19 ms·

121.
by 1_over_n 7y ago
This meaningless comparison is a fundamental concept in psychopharmacology. Different substances can have different effects whilst acting on the same pathway. And to your point re: "effects"it should be noted the SAME substance
122.
by 1_over_n 7y ago
There are other ways to proceed when your running low - in my experience it depends heavily on how hungry a bulldog you have built (i think paul graham said this) which is often a function of when you raised cash. If you have to make payrol
123.
by 1_over_n 7y ago
Coffee and coaine are not actually worlds apart in terms of mechanism of action, they both act on the same brain pathway though coffee has a limited ability to activate this pathway in comparison to cocaine.
124.
The Sievert(en.wikipedia.org)
2 points by 1_over_n 7y ago|0 comments
125.
by 1_over_n 7y ago
This narriative has also taken over the VC world.
126.
by 1_over_n 7y ago
Love this, many problems can be solved with regression analysis.
127.
UK target to start cancer treatment after urgent referral not hit since 2015(bbc.co.uk)
1 points by 1_over_n 7y ago|0 comments
128.
by 1_over_n 7y ago
Pigeons have been trained in pathology imaging for breast cancer https://journals.plos.org/plosone/article?id=10.1371/journal...
129.
by 1_over_n 7y ago
I worked in an animal lab on masters research that required strict 12/12 light cycles. 12 hours bright white, 12 hours red light (circadian rhythms impacted the study design). No windows and no support from post doc or supervisors (bot
130.
by 1_over_n 7y ago
Personally i think the frustrating thing here is that it sours the pool for others who are interested in medical innovation that requires data.
131.
by 1_over_n 7y ago
because VCs believe it gives them defensibility
132.
by 1_over_n 7y ago
well the post has hit top of HN
133.
by 1_over_n 7y ago
in a similar vein, i was also wondering how many are still on there and yet to be determined hoaxes. Someone with more time than me could see if you can use the existing hoax data to create an algorithm to flag hoax potential and run it on
134.
by 1_over_n 7y ago
just looked then to see if naked mole rats have upregulated p53 too as they are resistant to cancer and it seems to be regulated by same mechanism https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511137/
135.
by 1_over_n 7y ago
https://en.wikipedia.org/wiki/Another_Place_(sculpture) Gormleys another place is pretty cool. Pro tip: take a friend who doesnt know about it and ask why they think there are people standing motionless in the water.
136.
List of Hoaxes on Wikipedia(en.wikipedia.org)
181 points by 1_over_n 7y ago|72 comments
137.
by 1_over_n 7y ago
where does medtech / biotech / synthetic biology / drug development fit into this thinking too? Especially now YC are pushing into Bio. Long R&D timeline. Long path to revenue. Huge scaleability for those who get it right
138.
Bokklubben World Library(en.wikipedia.org)
1 points by 1_over_n 7y ago|0 comments
139.
Novel Immunotherapy Granted Fast Track Designation for Metastatic Melanoma(targetedonc.com)
1 points by 1_over_n 7y ago|0 comments
140.
FDA Release Draft Technical Performance Assessment of Quantitative Imaging [pdf](fda.gov)
2 points by 1_over_n 8y ago|0 comments
141.
by 1_over_n 8y ago
"makes it harder to kill" Unfortunately, this is still thinking in terms of the "cure" mindset as opposed to co-existing with cancer. Maybe you just can't kill cancer. Try not to think about "let it grow"
142.
by 1_over_n 8y ago
we are working in a similar space, the challenges of getting this to something that is beneficial to patients are immense. Getting the science working is one thing, regulation & reimbursement strategies for this are equally as intimidat
143.
by 1_over_n 8y ago
link to paper discussing new classification scheme based around evolution of cancers https://www.nature.com/articles/nrc.2017.69.pdf
144.
Thuggee(en.wikipedia.org)
1 points by 1_over_n 8y ago|0 comments
145.
by 1_over_n 8y ago
So the question becomes - will China respect the USA's patents, will the USA respect Chinese patents?
146.
by 1_over_n 8y ago
Yesterday i was researching IP strategies for AI companies and came across this paper from a legal firm. https://www.bereskinparr.com/files/file/IAM88_AI-and-IP_Jim%... It blew my mind how much China is filing pat
147.
by 1_over_n 8y ago
original paper here https://royalsocietypublishing.org/doi/pdf/10.1098/rspb.2017...
148.
Stanford Entrepreneurial Thought Leaders Talks(ecorner.stanford.edu)
2 points by 1_over_n 8y ago|0 comments
149.
by 1_over_n 8y ago
https://en.wikipedia.org/wiki/Pomodoro_Technique Pomodoro technique for the win. Just work for 25 minutes and then time box your procrastination for 5 minutes. Be disciplined and you will be surprised how far it gets y
150.
by 1_over_n 8y ago
Things that are happening on the edge become the things that propagate through to the mainstream. It's how cultures change. Predicting which edge behaviour will cross over is the tricky bit.

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