This meaningless comparison is a fundamental concept in psychopharmacology. Different substances can have different effects whilst acting on the same pathway. A

This meaningless comparison is a fundamental concept in psychopharmacology. Different substances can have different effects whilst acting on the same pathway. And to your point re: "effects"it should be noted the SAME substance can have very different effects (biphasic effects) depending on dose (alcohol being the key exmaple). https://en.wikipedia.org/wiki/Mesolimbic_pathway https://en.wikipedia.org/wiki/Mesolimbic_pathway https://jbiomedsci.biomedcentral.com/articles/10.1186/1423-0127-17-4 https://jbiomedsci.biomedcentral.com/articles/10.1186/1423-0... https://www.ncbi.nlm.nih.gov/pubmed/9884132 https://www.ncbi.nlm.nih.gov/pubmed/9884132