8 ms·
Bacteria found in the human intestine capable of improving muscle strength
- culi 7mo agoIt works by converting fibers into butyrate. You should maintain a high fiber diet to promote Roseburia in your gut
- adrian_b 7mo agoIt is known that the bacteria that produce high amount of butyrate are beneficial, e.g. by decreasing the risk of colon cancer, but this does not seem sufficient to explain the increase in muscle strength that seems to be caused by this species alone. The study has first found in humans a correlation between muscle strength and the presence of this bacterium. Then they have attempted to determine whether this correlation is due to a causal relationship by killing the gut bacteria in mice, then feeding them with this kind of human gut bacteria. The result was an increased muscle strength, which seems to confirm causality. How the bacteria increase muscle strength remains unknown. I think that a possible explanation may be that this bacterium produces some substance that mimics a human hormone, e.g. a steroid, in which case it would be a kind of natural doping.
- sandworm101 7mo agoNatural or otherwise, one must wonder if there are similar downsides.
- adrian_b 7mo agoTrue.
- DiscourseFan 7mo agoI've always eaten a ton of fiber, to the point where if I stop I get constipated, and I've always put on muscle fairly easily.
- b65e8bee43c2ed0 7mo agothe fiber will promote all bacteria in your gut, not just this particular strain.
- blargey 7mo agoAll fiber-consuming gut bacteria, yes - but that's basically synonymous with "good"/beneficial gut bacteria, so it's good advice even if it doesn't give people the massive gainz they might have been hoping for.
- moffkalast 7mo agoYou know it would be funny if at least once the finding would be "you should eat more hamburgers" or something.
- HK-NC 7mo agoA home made hamburger can be incredibly healthy.
- array_key_first 7mo agoIt can be, but it's often not. The thing that makes hamburgers harmful isn't really the "chemicals" or processing or whatever, it's the fact that it's red meat with high amounts of saturated fat. You would have to use low fat beef, and ideally not beef but turkey. I think some people think that burgers, fries, steak, and milkshakes are bad for you because they're fast food or restaurant food. No... no that stuff is just bad for you. You'll get a heart attack if you make it at home, too. Just eat it in moderation and eat more vegetables.
- culi 7mo agoIMHO it's the restaurant. For a variety of reasons but here's just one example of a mechanic: > Repeatedly heated cooking oils (RCO) can generate varieties of compounds, including polycyclic aromatic hydrocarbons (PAH), some of which have been reported as carcinogenic. RCO is one of the commonly consumed cooking and frying medium. These RCO consumption and inhalation of cooking fumes can pose a serious health hazard. https://pubmed.ncbi.nlm.nih.gov/28925728/ https://pubmed.ncbi.nlm.nih.gov/28925728/ Nutrition is complicated and rules of thumb can be really useful even if they sometimes over simplify things. One good rule that has had a ton of research interest into it in the past decade or so is ultra-processed foods. Here's a BMJ review > Greater exposure to ultra-processed food was associated with a higher risk of adverse health outcomes, especially cardiometabolic, common mental disorder, and mortality outcomes. These findings provide a rationale to develop and evaluate the effectiveness of using population based and public health measures to target and reduce dietary exposure to ultra-processed foods for improved human health. They also inform and provide support for urgent mechanistic research. https://www.bmj.com/content/384/bmj-2023-077310 https://www.bmj.com/content/384/bmj-2023-077310
- functional_dev 7mo agoSo.. eat more fiber and your gut bacteria will produce butyrate. And that helps muscles.
- rendall 7mo ago...in mice. :/
- jb1991 7mo agoThe reflex “in mice” meme has been annoying for quite some time.
- Aboutplants 7mo agoMaybe we need to flip it and start testing new mouse drugs on Humans?
- wellthisisgreat 7mo agoThe mouse lobby rears its [tiny] head again
- RobRivera 7mo agoWe need deeper research into mouse bites as medicine.
- wpm 7mo agoMore mouse bites!
- ben_w 7mo agoUnironically, SMBC is one of the two most important philosophical treatise in modern western culture: https://www.smbc-comics.com/?id=2881 https://www.smbc-comics.com/?id=2881
- stefs 7mo agoAs always. But it's a first step.
- adrian_b 7mo agoIt is not that simple. They have found first a correlation between the presence of this species of bacteria and muscle strength in humans. Then they have made an attempt to determine whether this correlation reflects a causal relationship. So they have fed mice previously treated with antibiotics, to remove their own gut bacteria, with this kind of bacteria extracted from humans. They have indeed seen an increase in muscular strength at the mice that have received the human bacteria, which seems to confirm causality between the presence of this bacterium and muscle strength. While they have also determined the biochemical changes in muscles that have caused increased strength, the mechanism of how the bacteria have influenced that remains a mystery. Perhaps this bacterium produces some substance that mimics a human hormone, e.g. a steroid. Paywalled research article: https://gut.bmj.com/content/early/2026/03/03/gutjnl-2025-336980 https://gut.bmj.com/content/early/2026/03/03/gutjnl-2025-336...
- grg0 7mo agoThis is why I tell my gym bros that they should quit all that Celsius garbage and stick to the basics. You should measure your gut health by the quality of your feces (consistency, texture, colour, shape), and then your muscles and rest of your body will thank you. This research is evidence of that. The science is still catching up.
- stefs 7mo agoCelsius?
- grg0 7mo agoCorrected, thank you.
- acessoproibido 7mo agoWhat do you mean by celcius garbage? Fun fact: in Germany most toilets have a built in 'inspection plate' so you can look at your shit before you flush it. In other places I often found it hard to judge the quality because you can't even see it well or it gets flushed instantly
- grg0 7mo agoI meant Celsius, a popular energy drink in the US, but more generally that and the processed foods people take in for some supposed performance gains.
- SV_BubbleTime 7mo agoIt’s gross sugar water. I accidentally bought some once and years later I found out people are intentionally drinking it.
- simulator5g 7mo agoIt's not sugar, they use synthetic sweeteners. I started getting gout symptoms after picking up a Celsius habit, then quit that without making any other changes, and the symptoms went away.
- toomuchtodo 7mo agoRoseburia inulinivorans probiotic when? Probably add it to the premade protein shakes and mix specific to those building muscle. https://en.wikipedia.org/wiki/Roseburia_inulinivorans https://en.wikipedia.org/wiki/Roseburia_inulinivorans
- Giorgi 7mo agoWell... assuming this article is just shilling, soon.
- RobRivera 7mo agoGAINS
- youalmosthadit 7mo agoNo grain no gain
- FurstFly 7mo agoMy gym bros gonna be so shocked lol
- shevy-java 7mo agoSo Homer Simpson was right in the end. Beer is basically fermented sugar (well, glucose converted to ethanol by yeast, for the most part; though its maltose first, yeast, bacteria etc... prefer glucose and maltose is a disaccharide of glucose: Maltose).
- mikrl 7mo agoPretty sure Duff was a heavily filtered macro beer. Not saying engineered beer is necessarily bad- Sapporo and Asahi never disappoint- but I imagine you would want to stick to unfiltered and unpasteurized to retain some of the more… alive compounds.
- deleted 7mo ago[deleted]
- joshuahaglund 7mo agoNo beer has nothing to do with Roseburia genus bacteria
- TMWNN 7mo ago>So Homer Simpson was right in the end. Indeed. Proof that beer builds gut strength: <https://www.youtube.com/watch?v=OrrEzyKXUnk https://www.youtube.com/watch?v=OrrEzyKXUnk>
- xthe 7mo ago[dead]
- rramadass 7mo agoPerhaps there is also a direct correlation between this microbiome and longevity in the so-called "blue zones" of the world like Okinawa, Sardinia etc. We are what we eat.
- tvshtr 7mo agoSome of the blue zones were disproven, due to falsified documentation or lack of it.
- patmorgan23 7mo agoIIRC there are several of the "Blue Zones" where just bad government records. (People who had incorrect birth dates, or had already died and the government just didn't know about it)
- SV_BubbleTime 7mo agoJose DeSanquin Demarco of Bolivia is now the world’s oldest man at 117, he attributes his health to 10 hours daily in the sun and fields farming quinoa. Photographed here, Jose’s 90 year old wife holds their newborn twins.
- jareklupinski 7mo ago> We are what we eat. putting together a theory on how bacteria organized multicellular life to exploit our macro-movements and proliferate between damp spots
- rramadass 7mo agoDo you mean you work in this domain and are working on the above theory?
- jareklupinski 7mo agomy only credential is a bio-eng degree, but i read a lot and hope to put together a novel or something to get ppl thinking about it, until we can find a way to test the hypothesis
- roschdal 7mo agoI need this
- nate8bit 7mo agoEat some apples and add 10lb to your bench. Nice!
- sublinear 7mo ago> This opens up the possibility that the bacterium under investigation could be used as a probiotic to help preserve muscle strength during aging Maybe, but it's really hard to control for other variables here. They don't know what's causing this bacteria to diminish over time in older adults in the first place. It could totally just be dietary habits getting worse over time as people let themselves go. Regardless of age, most people already don't eat enough protein and when they do they might not be getting "complete" proteins either (missing amino acids is common with plant-based foods).
- fylo 7mo agoFor me personally, as I've gotten older I have continued to eat better and more consistently than I ever did earlier in life. I think the long term study of your own life tends to show you that diet is one of, if not the, primary factor in short and long term health and well being.
- DennisP 7mo agoThat's why they followed up with an actual experiment with mice, where they found that just adding the bacteria made them stronger. Of course we won't know for sure before doing human experiments, but it'd be an odd coincidence if we saw the correlation in humans and causation in mice, but there was no causation in humans.
- ramoz 7mo agoDid quick research on how to support the bacteria growth > Dietary modifications that emphasize high-fiber and prebiotic foods and dietary supplements may support the healthy growth of Roseburia [1] > As stated above, a Mediterranean diet is associated with increased Roseburia growth. This diet emphasizes primarily plant-based foods: whole fruits and vegetables, whole grains, legumes, nuts and seeds, olive oil, and fatty fish. The high fiber and resistant starch content of these foods may fuel Roseburia and the other beneficial flora of the human microbiome [1] > Polyphenols are plant compounds abundant in fruits, vegetables, tea, and coffee. Emerging research indicates that polyphenols can enhance Roseburia abundance indirectly by inhibiting harmful bacteria and fostering beneficial ones. [2] [1] https://www.rupahealth.com/post/roseburia-spp-101 https://www.rupahealth.com/post/roseburia-spp-101 [2] https://www.innerbuddies.com/pages/gut-microbiome-101/gut-bacteria-key-gut-species-increase-roseburia https://www.innerbuddies.com/pages/gut-microbiome-101/gut-ba...
- OfirMarom 7mo agoThanks for the dietary info! Helps make it concrete.
- underlipton 7mo agotl;dr They don't know. I wish scientists would be more open about how little they understand digestion and nutrition, particularly on an individual level. Advice gets presented as an if-then, when it's not.
- kbenson 7mo agoIf you have a complaint against "scientists" as hsme homogenous group, I think I'm going to have to ask you to explain how these particular scientists did not do that, and why you would think this is a problem of scientists (a label for a largelt disparate group not connected through any specific communication or hierarchy and mostly in output) in general?
- drecked 7mo agoNutrition researchers know a lot about diet. Or at least what constitutes a good diet. The reason you think “they don’t know” is a media ecosystem that hypes weak minor contrary results that usually disappear in further research and an entrenched trillion dollar food industry that spreads misinformation to get you to continue eating the foods they sell that have the highest markups, such as processed foods, meat and dairy.
- soopypoos 7mo agoNeisseria gonorrhoeae doesn't even have muscles but it can pull 100,000x its own weight
- emanuele-em 7mo agoEvery few months there's a new study showing gut bacteria control yet another thing we thought was "us." Mood, cognition, immune response, and now muscle strength. Starting to wonder what's even left.
- dd8601fn 7mo agoAnd yet, still no serious fixes for any of it that aren’t just jabronis pitching overpriced and ineffective supplements.
- wiml 7mo agoRecommendation #1 is almost always "eat a healthy, varied diet high in vegetables, fiber, etc". Pretty f'in straightforward if you ask me.
- array_key_first 7mo agoYes, I think some people are waiting for doctors to tell them that they can eat hamburgers and drink milkshakes and be healthy. Remember when Mom said to eat your vegetables? Turns out she was right.
- g-b-r 7mo agoWill people really go after Tom Brady's stuff now? xD
- sharpshadow 7mo agoActive cultures are available[0] and there is certainly a way to make them available to the gut isn’t there? 0. https://webshop.dsmz.de/en/bacteria/Roseburia-inulinivorans.html https://webshop.dsmz.de/en/bacteria/Roseburia-inulinivorans....
- blitzar 7mo agoGym bros are going to be eating their own faeces for the gainz.