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Humans May Be Able to Grow New Teeth Within Just 4 Years
- Fraterkes 10mo agoConfused a bit by the article: it mentions human trials began in september 2024, but also that the trials that might prove it working are yet to start?
- magicalhippo 10mo agoI think it's just poorly written. If you go to the source[1] the trial period was planned from September 2024 to August 2025, and the submission says people are "undergoing" a trial. Perhaps it got delayed, or, more likely IMHO, the trial period is over and they're studying the data so haven't made reached a conclusion yet. [1]: https://www.kitano-hp.or.jp/info/20240503 https://www.kitano-hp.or.jp/info/20240503
- MajesticHobo2 10mo agoIt’s a phase 1 clinical trial designed only to assess safety and determine the appropriate dosage. Future trials will focus on efficacy.
- zingababba 10mo agoI've been taking vitamin k2 mk4 at 45mg a day for over a year now. My teeth feel gr8. Now I need to get some of this stuff to have super human chompers.
- epicureanideal 10mo agoWhat changes in your subjective sensation of your teeth with K2?
- giardini 10mo agoThis guy's been downvoted badly but he's right - vitamin k2 make your teeth into "superteeth". I started K2 about 10 years ago. Next dental checkup (about a year too late) the dental tech said my teeth appeared recently-cleaned. This has continued since then. No cavities, little cleaning required other than regular brushing, flossing and taking k2.
- resoluteteeth 10mo agoIIRC plaque is mineralized by saliva in the same way as tooth enamel, so something that changes saliva in a way that prevents tartar from forming might be reducing the amount of calcium in your saliva in a way that could potentially ultimately not be good for your teeth.
- terribleperson 10mo agoWhy mk4 over mk7?
- bumblehean 10mo agoAren't the shape/size/placement/etc. of human teeth fairly unique across different individuals? At least unique enough to use dental records to identify bodies. I don't see if mentioned in TFA, but if new human teeth can be grown is it expected that the new ones will just grow in "correctly" to fit a person's mouth?
- clickety_clack 10mo agoTeeth wear quite a bit too, I wonder will new ones have to be pared down to fit.
- throwup238 10mo ago> At least unique enough to use dental records to identify bodies. Yes but in comparative dental analysis they use ante-mortem dental records to compare with post-mortem remains. It's not like DNA where you can record it once and then use that to match samples decades later in a database. In order to have a high confidence in a match, recent x-rays and records of dental work like fillings, crowns, etc. work best. And no it is not expected. It's one of the primary challenges with bringing these kinds of drugs to market, as hyperdontia is already relatively common among humans (I had an incisor growing at the roof of my mouth an inch behind my row of teeth). Most successful applications of these tooth regrowth drugs tend to place them near the root of missing teeth hoping that the cellular growth signaling mechanisms are still working.
- msuniverse2026 10mo agoScientists regrowing everything except hair. Fuck my life.
- xenospn 10mo agoAnd limbs.
- piskov 10mo agoI would say every tissue: no bones, no organs, eyes, ears, nerves, skin. Like what can they grow?
- janice1999 10mo agoThe liver is an exception here - you can grow back a lot of it.
- piskov 10mo agoNot many times tho: see cirrhosis
- kylecazar 10mo agoWell, I'm personally hoping stem cells pull through for corneal tissue regrowth. I've got significant scarring in one eye. I'd rather not get a donor (cadaver) cornea sewn on if it's avoidable but we'll see. I think they're making progress.
- drdeca 10mo agoEh? They can grow skin cultures that are good enough to help burn victims. Not, like, with all the pores and follicles being there, but it is skin…
- zaken 10mo agofinasteride + minoxidil
- m3kw9 10mo agoGrowth rate and how you don’t mess it up before it matures are problems
- TylerE 10mo agoThis is like fusion energy. It's been 4 years away since I've been a child.
- amelius 10mo agoI personally regrew my teeth since I was a child. Granted, once.
- gambiting 10mo agoFun fact - all of your adult teeth were already there from the start, hiding under(inside?) the gums. We don't "grow" new teeth when the baby teeth fall out - the adult teeth were always there under them.
- dekhn 10mo agoDid they get bigger as you were "Growing up"? Then we grow teeth, you're just being pedantic about whether they're brand new or not.
- Dylan16807 10mo agoIt's not pedantic in this context unless you already have a way to set up fresh seed teeth.
- tstrimple 10mo agoIt may be fun, but it's not a fact. At birth, you likely have all the tooth buds to grow your primary teeth and maybe your permanent molars. Premolar and canine buds typically form during the first year of life. Second molar buds form around age two. Third molar (wisdom teeth) buds don't begin developing until around age five to six and in some folks they don't grow at all. I have a condition where my lower front permanent teeth never developed. We weren't sure if any of our kids would have the same issue so we discussed it with the dentist. They couldn't tell us if all the permanent teeth were present or developing because there hadn't been enough time for first xrays to show all of the permanent teeth buds growing. Even at age 3.
- piskov 10mo agoLet’s hope teeth won’t grow in places they shouldn’t.
- wellthisisgreat 10mo agoa haircut made of teeth though, hmm
- krater23 10mo agoWe all shoult fear the vagina dentata.
- kevin_thibedeau 10mo agoLet me introduce you to the teratoma: https://en.wikipedia.org/wiki/Teratoma https://en.wikipedia.org/wiki/Teratoma
- RomanPushkin 10mo agoDon't need teeth yet (lol), but curious if anyone is aware of a similar/new ways to restore the enamel?
- petermcneeley 10mo agohttps://www.bbc.com/news/articles/cn09kwrg57do https://www.bbc.com/news/articles/cn09kwrg57do
- eulgro 10mo agoMix hair in your toothpaste https://www.bbc.com/news/articles/c9qy0w27213o https://www.bbc.com/news/articles/c9qy0w27213o
- throw4847285 10mo agoPopular Mechanics is like Popular Science right? Extremely bullish on new technologies to the degree of taking one study and turning it into a breathless article about how we're 1 year away from flying cars? Sorry for the cynicism, but I grew up subscribing to Popular Science and I gained a very jaundiced view of this kind of science/technology popularizing
- intothemild 10mo agoYep, you nailed it.
- fellowniusmonk 10mo agoYes, they loved the moller sky car, frankly these magazines would have been great if they just accurately caveated stage of development and leaned into a speculative "The World of Tomorrow" attitude for these types of things. As a result of NOT doing that they really poisoned people against the very idea of progress (of which we make a ton.)
- twosdai 10mo agoI wonder if at the time the "world of tomorrow" is how we think of it now with fondness.
- abootstrapper 10mo agoI’ve heard this for the last 20 years.
- valunord 10mo agoOld news. They were doing this with ultrasound successfully 20 years ago. I know a guy who a tooth back with his own device.
- u8080 10mo agoCould you give more details? Sounds interesting.
- galkk 10mo agoUnrelated to the growth topic, but related to teeth. 5 or something years ago I read here, on hn, about novamin/biomin and started to buy toothpaste with it. Since that I had 0 cavities, even if my toothcare routine isn’t the best: most of the time I brush only in evening and when I had severe clinical depression episode I could go weeks without brushing.
- wakawaka28 10mo agoDo you eat much sugar? Soda or juice? These things make a huge difference. So does age. Young people get cavities easier than somewhat older people.
- anonzzzies 10mo agoIs there also not a some genetic aspect there? It is a question as I do not know but always assumed as I always did whatever and have 0 cavities or anything else that other people seem to have and I am almost 60. Never have receding gums, sensitivity, cavities or anything else since I was born.
- wakawaka28 10mo agoThere is a genetic aspect I'm sure. But I think most people don't avoid consequences of, say, drinking lots of soda while not brushing teeth. I bet there are nutritional factors too. If you are chronically malnourished, your teeth may be worse somehow. I think regularly brushing your teeth and getting cleanings makes a big difference obviously. Gum disease or gingivitis mainly happens to people who have long-term dental care issues or certain bad habits.
- wolvoleo 10mo agoIt's actually really bad to brush teeth just after drinking soda because the acidity of the CO2 softens the enamel. Better to wait a while. That's what my dentist said anyway.
- ezoe 10mo agoI've been hearing this for as long as I can remember and I'm not young anymore.
- nephihaha 10mo agoGreat idea but I'm sure it will be for the rich.
- BugsJustFindMe 10mo agoBugsJustFindMe's Law of Headlines: Any headline that uses the words "May", "Might", or "Could" is equally true if those words are replaced by "Won't".
- coolThingsFirst 10mo agoSame like curing baldness, every 5 years there's a new medicine which doesn't work. Teeth are orders of magnitude more complex than hair follicles.