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High blood pressure may contribute to cognitive decline
- taurath 3y agoOr high blood pressure is related to stress, anxiety, trauma etc which all also contribute to cognitive decline!
- cuchoi 3y agoIt seems that they increase blood pressure by giving rats a high-salt diet.
- deleted 3y ago[deleted]
- CrzyLngPwd 3y agoIs there anything that won't contribute to cognitive decline?
- okr 3y agoStay young and don't breathe.
- garganzol 3y ago> don't breathe Lack of oxygen immediately contributes to cognitive decline.
- Scoundreller 3y agoOnly in the long-term (ie: more than 5 seconds). But for those initial seconds, you're a bit better off!
- emmelaich 3y agoSwings and roundabouts. ¯\_(ツ)_/¯
- basedkissinger 3y ago[dead]
- nradov 3y agoAtmospheric nitrogen is a very mild anesthetic which reduces cognition. If we could replace nitrogen with helium in the gas we breathe then we would all be a tiny bit smarter.
- corethree 3y agoPlenty of things are associated with cognitive growth. For example: gaming and reading.
- pstuart 3y agoExercise, which will help prevent it.
- pharrington 3y agoThe article's real title is "Salty immune cells surrounding the brain linked to hypertension-induced dementia".
- dangerwill 3y agoOh joy, yet another reason why I'm getting dumber, I'll add it to the pile
- garganzol 3y agoHigh blood pressure may be not a cause of cognitive decline, but just a consequence. This is what happens in malnutrition. Absence of nutrients and coenzymes (vitamins) leads to energy deficit and results in cellular damage, nervous system tries to compensate that by increasing blood flow, so it induces high blood pressure to have better chances of survival with increased blood perfusion and substrates delivery rate (glucose, lipids, oxygen, coenzymes). Immune system gets activated by metabolically impaired tissues creating even more damages at the affected areas. Changing electrolyte balance of the body by giving extremely high amounts of salt is a sure way to disrupt the metabolism with all the consequences.
- rqtwteye 3y ago"High blood pressure may be not a cause of cognitive decline, but just a consequence." Isn't that the same?
- TeMPOraL 3y ago"Cause" is the literal opposite of "consequence", unless you're postulating a feedback loop.
- arcticbull 3y agoDepends how you read the line. If you read it this way, they are the same. > "High blood pressure may be not [be] a cause of cognitive decline, but [cognitive decline may] just [be] a consequence [of high blood pressure]." The other interpretation makes less sense. > "High blood pressure may be not a cause of cognitive decline, but just a consequence [of cognitive decline]." The implication here is that cognitive decline causes high blood pressure, which doesn't make any sense. The author I think was trying to say they have a common cause, but I don't believe there's any evidence for the mechanism on which their thesis relies.
- garganzol 3y agoThe implication is that a dying brain (= cognitive decline) initiates a flight or fight response which includes adrenaline flare ups and high blood pressure as a result.
- financltravsty 3y agoHypertension -> blood vessel necrosis -> reduction in blood supply and nutrients to organs such as the brain -> declining mental health? An interesting note is that of runaway hypertension when the kidneys become damaged by hypertension, decrease their ability to modulate blood pressure, thereby increasing hypertension, which damage the kidneys, which... so on.
- rabuse 3y agoI'm of the belief obesity causes more than 90% of the health woes in western nations.
- mobilejdral 3y ago> In this study, mice were fed a high-salt diet High salt levels increase Aldosterone (https://pubmed.ncbi.nlm.nih.gov/11327640/ https://pubmed.ncbi.nlm.nih.gov/11327640/) > However, blocking the brain blood vessels’ ability to respond to IL-17 only partially rescued cognitive impairment, suggesting that there was another source of IL-17 acting on the brain. Just a guess, but To produce Aldosterone the body also over produces cortisol resulting in less somatostatin, lowering IGF-1. IGF-1 stimulates the growth and division of both oligodendrocytes and schwann cells so lower IGF-1 would decrease myelin growth and induce cognitive impairment.
- iamdbtoo 3y agoThis is very related to a theory I have that as my blood pressure has gotten higher over the years my ADHD also gets more difficult to manage. Guanfacine has also helped my symptoms more than anything and it was first brought to market as a blood pressure medication.
- c_o_n_v_e_x 3y agoI have elevated blood pressure and what I suspect to be an undiagnosed case of ADHD. I've never made the connection until reading your comment. I thought perhaps it's just been years of doomscrolling that has destroyed my attention span. Maybe both? I routinely get blood pressure spikes in the late afternoons. It's hard to describe but when it happens I feel like I need my vision to "zoom out", it's almost overwhelming / fatiguing to maintain what I'm looking at. I feel "spaced out" cognitively when this happens.
- brainbag 3y agoDo you have any more information about this? It would explain the challenge I've been experiencing as I enter my early 40s with a family history of hypertension; my blood pressure has been going up, which makes sense, but my ADHD has also been getting harder to manage, which doesn't.
- iamdbtoo 3y agoSorry for the late response, but I don't have any more information about it as it's mostly anecdotal based on my experience. The best explanation I have come up with is the high blood pressure lowers the amount of oxygenated blood in the brain making it harder to produce dopamine, which it is already struggling to do.
- hombre_fatal 3y agoI have a similar issue. Amphetamine gives me more side effects and seems to help less these days despite being a wonder drug thru my 20s. I’ve optimized my diet and exercise regularly, half because of this, but it only goes so far. I’m running out of levers to pull.
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- dogmatism 3y agoterrible headline. This is known. What the study elucidates is how (aside from strokes, afib, heart attacks, etc etc that are a consequence of high blood pressure)
- kissingerlives 3y ago[flagged]
- thinkpad13 3y agohow to help and treat people with high blood pressure? any idea? I want to take care and help my mom