6 ms·

I am amazed at the level of R&D & economies of scale with vaporizers. The tech in these - high-power electronics, computer controlled heating profiles etc is q

by LASR 4y ago

I am amazed at the level of R&D & economies of scale with vaporizers. The tech in these - high-power electronics, computer controlled heating profiles etc is quite sophisticated. Societal evils aside, this could be a very precise drug-delivery system that can be cheaply mass-produced.

newsclues 4y ago
It blows my mind the market is so slow because of legal issues. It’s billions of dollars a year
- akhmatova 4y ago
  Well the customer base isn't too picky, by and large.
lmg643 4y ago
That's a great and positive way to look at vaping. Every time I hear about "medical marijuana" I think about the probable link to schizophrenia, which will likely dwarf the pot economy in both direct and indirect costs. -- edited to add citations -- Spent about 10 seconds finding these using Brave search. For folks who can't resist snarky comments, you have to admit it's strange that this is not at least acknowledged amidst a state-by-state push for legalization. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2424288/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2424288/ >> "There is now reasonable evidence from longitudinal studies that regular cannabis use predicts an increased risk of schizophrenia and of reporting psychotic symptoms. These relationships have persisted after controlling for confounding variables such as personal characteristics and other drug use. The relationships did not seem to be explained by cannabis being used to self-medicate symptoms of psychosis." https://jamanetwork.com/journals/jamapsychiatry/article-abstract/2782160?guestAccessKey=13668b0c-b3e4-45c9-a35c-e4c44d500ea9&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=072121 https://jamanetwork.com/journals/jamapsychiatry/article-abst... >> "The results from these longitudinal analyses show the proportion of cases of schizophrenia associated with cannabis use disorder has increased 3- to 4-fold during the past 2 decades, which is expected given previously described increases in the use and potency of cannabis."
- _eht 4y ago
  Every time my wife smokes the devil’s lettuce she craves a black man. Citation needed, btw.
- hsbauauvhabzb 4y ago
  I’ve always felt like research into drugs has always had polarising bias in both directions.
  - yieldcrv 4y ago
    It is very immature research when you compare it with the designer drugs that go through the federal FDA process, where there are multiple phases of clinical trials all for a single use case. And then all the side effects that are found in a controlled study are listed on the side of the packaging. The state process is completely absent of any research, and the community is relying on anecdotes for an infinite set of use cases. Side effects listed, if any, are based on the same anecdotes. I’ll give that an F for Failure. I’m not for putting dealers or users in prison, I can acknowledge that the consumer protection is absent.
    - monetus 4y ago
      How would the fda go about testing the convergent effects of all the different chemicals when the ratios shift significantly and the means of consuming them change what actual chemicals reach which parts of the body? Distill/synthesize each one, mix them in every permutation, and dose representative patients in every possible way?
      - R0b0t1 4y ago
        By applying the boot to your neck, overdoses are reduced by 50%. Getting an accredited healthcare professional to tell you the boot is good for you reduces it a further 25%.
      - hsbauauvhabzb 4y ago
        Doesn’t that invalidate any existing research also?
asdff 4y ago
To be fair most thc vapes are just a battery putting out fixed voltage and a button. The fancy ones are nice ofc but nothing more than a samsung 18650 battery and a variable voltage controller, maybe microusb charging instead of screw on too.
the_gipsy 4y ago
It's not much tech, just a regulated battery and a wire/coil with cotton soaked in juice.
PragmaticPulp 4y ago
> Societal evils aside, this could be a very precise drug-delivery system that can be cheaply mass-produced. It’s not really that precise at all because it’s up to the user to control how long to inhale. The only reason vape users can dose somewhat precisely is that the drug had a short and obvious feedback loop (how they feel) and they dose many times over the life of a cartridge, allowing them to learn how to dose properly. THC is also very forgiving in overdose, which isn’t a feature shared by most drugs.
- dr_dshiv 4y ago
  Hypothesis: Bluetooth authenticated dosage controlled vapes will be big. Many drugs can be vaped in that manner safely.
  - konfusinomicon 4y ago
    enter your current weight..potency verified via blockchain..DNA and prescription record cross referenced for interactions and sensitivities..a set of smiley faces similar to the pain chart they have at hospitals shows on display portraying various level of stonedness.. pick one and 3, 2, 1 inhale, exhale, and blast offffff
    - vonseel 4y ago
      If you had could go back a few years you might be able to raise funding with that blockchain comment
      - aaaaaaaaata 4y ago
        Or forward.
        konfusinomicon 4y ago
        or NOW!! i present to you Potentately.io . it's a very lucrative investment and if you act now you can get in on the bottom floor of a tower to the moon built upon the expanded minds of stoners worldwide.
soared 4y ago
I wonder if some drugs would only work in vapes, rather than inhalers or nebulizers.
pantalaimon 4y ago
DMT vape liquid is already enjoying quite some popularity.

by LASR 4y ago

newsclues 4y ago

It blows my mind the market is so slow because of legal issues. It’s billions of dollars a year

akhmatova 4y ago
Well the customer base isn't too picky, by and large.

lmg643 4y ago

That's a great and positive way to look at vaping. Every time I hear about "medical marijuana" I think about the probable link to schizophrenia, which will likely dwarf the pot economy in both direct and indirect costs. -- edited to add citations -- Spent about 10 seconds finding these using Brave search. For folks who can't resist snarky comments, you have to admit it's strange that this is not at least acknowledged amidst a state-by-state push for legalization. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2424288/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2424288/ >> "There is now reasonable evidence from longitudinal studies that regular cannabis use predicts an increased risk of schizophrenia and of reporting psychotic symptoms. These relationships have persisted after controlling for confounding variables such as personal characteristics and other drug use. The relationships did not seem to be explained by cannabis being used to self-medicate symptoms of psychosis." https://jamanetwork.com/journals/jamapsychiatry/article-abstract/2782160?guestAccessKey=13668b0c-b3e4-45c9-a35c-e4c44d500ea9&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=072121 https://jamanetwork.com/journals/jamapsychiatry/article-abst... >> "The results from these longitudinal analyses show the proportion of cases of schizophrenia associated with cannabis use disorder has increased 3- to 4-fold during the past 2 decades, which is expected given previously described increases in the use and potency of cannabis."

_eht 4y ago
Every time my wife smokes the devil’s lettuce she craves a black man. Citation needed, btw.
hsbauauvhabzb 4y ago
I’ve always felt like research into drugs has always had polarising bias in both directions.
- yieldcrv 4y ago
  It is very immature research when you compare it with the designer drugs that go through the federal FDA process, where there are multiple phases of clinical trials all for a single use case. And then all the side effects that are found in a controlled study are listed on the side of the packaging. The state process is completely absent of any research, and the community is relying on anecdotes for an infinite set of use cases. Side effects listed, if any, are based on the same anecdotes. I’ll give that an F for Failure. I’m not for putting dealers or users in prison, I can acknowledge that the consumer protection is absent.
  - monetus 4y ago
    How would the fda go about testing the convergent effects of all the different chemicals when the ratios shift significantly and the means of consuming them change what actual chemicals reach which parts of the body? Distill/synthesize each one, mix them in every permutation, and dose representative patients in every possible way?
    - R0b0t1 4y ago
      By applying the boot to your neck, overdoses are reduced by 50%. Getting an accredited healthcare professional to tell you the boot is good for you reduces it a further 25%.
    - hsbauauvhabzb 4y ago
      Doesn’t that invalidate any existing research also?

asdff 4y ago

To be fair most thc vapes are just a battery putting out fixed voltage and a button. The fancy ones are nice ofc but nothing more than a samsung 18650 battery and a variable voltage controller, maybe microusb charging instead of screw on too.

the_gipsy 4y ago

It's not much tech, just a regulated battery and a wire/coil with cotton soaked in juice.

PragmaticPulp 4y ago

> Societal evils aside, this could be a very precise drug-delivery system that can be cheaply mass-produced. It’s not really that precise at all because it’s up to the user to control how long to inhale. The only reason vape users can dose somewhat precisely is that the drug had a short and obvious feedback loop (how they feel) and they dose many times over the life of a cartridge, allowing them to learn how to dose properly. THC is also very forgiving in overdose, which isn’t a feature shared by most drugs.

dr_dshiv 4y ago
Hypothesis: Bluetooth authenticated dosage controlled vapes will be big. Many drugs can be vaped in that manner safely.
- konfusinomicon 4y ago
  enter your current weight..potency verified via blockchain..DNA and prescription record cross referenced for interactions and sensitivities..a set of smiley faces similar to the pain chart they have at hospitals shows on display portraying various level of stonedness.. pick one and 3, 2, 1 inhale, exhale, and blast offffff
  - vonseel 4y ago
    If you had could go back a few years you might be able to raise funding with that blockchain comment
    - aaaaaaaaata 4y ago
      Or forward.
      - konfusinomicon 4y ago
        or NOW!! i present to you Potentately.io . it's a very lucrative investment and if you act now you can get in on the bottom floor of a tower to the moon built upon the expanded minds of stoners worldwide.

soared 4y ago

I wonder if some drugs would only work in vapes, rather than inhalers or nebulizers.

pantalaimon 4y ago

DMT vape liquid is already enjoying quite some popularity.