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Science Vigilante Calls Out Bogus Results in Prestigious Journals
- bayesian_horse 7y agoShe should get funding from someone like the Gates Foundation. After all, she could save them money and time.
- KuhlMensch 7y ago> Within her manual search of more than 20,000 pieces of biomedical research, 4% contained manipulated images. Shocking. And even if she reports the lies, they are not likely to be actioned: > Despite Bik’s work finding these manipulations, she estimates that only 30% of those papers have been corrected or retracted And she does it off her own back in more ways than one: > Living off savings, Bik reckons she has about a year’s leeway to work on her image manipulation sleuthing and hopes to find a way of monetizing her expertise as a science misconduct consultant to journals. and: > she writes and reports under her own name. In some ways, then, Bik is a surrogate for so many. She posts and reports publicly, often after being tipped off to papers from those who aren’t able to do it themselves
- teekert 7y agoIt's shocking but imagine you are a PhD student, you need 4 papers out in 4 years but you are operating in a field where your results are only accepted when they are positive and new (sometime even only when the confirm a certain theory!). It feels really unfair as it is essential a probabilistic process whether you will get a PhD or not, it depends only to a certain degree o how had you work and how smart you are. This needs to change. There are moments when you feel like giving up, for example when you receive a DNA construct that has been proven to work in some Science paper. You set up your experiment and for 1.5 years you wonder why it does not work for you. And you can only conclude that the Science paper didn't in fact produce a working construct, you start to see in the images of said paper that indeed, they may be coincidental and not the result of a working protein. And it sets you back 1.5 years. Or, you write around it, creatively as you explore the borders of your own ethics.
- arkh 7y ago> It's shocking but imagine you are a PhD student, you need 4 papers out in 4 years but you are operating in a field where our results are only accepted when they are positive and new. Get the fuck out of this field. Those stupid things keep on being only because some people are willing to be abused. When a lot less people enroll for those programs maybe some change will happen. Or maybe those students could start rioting.
- teekert 7y agoSo you would be the brave one, the one that will tell his professor: F U, I wont stay for 3 more years on this slave wage, you're going to have to make me a PhD based on my hard work that amounted to a set of results that you deem unpublishable. Good luck.
- ipunchghosts 7y agoThis cant be a serious article. This woman worked for ubiome and they recently had to shut down because they were being investigate for fraud by the FBI!
- dekhn 7y agoOne of the reasons I'm no longer a scientist: as a postdoc I was called on to read a paper about the functional impact of deleting genes in yeast, take their published data tables, and make sense of their results. The paper was fairly straightforward to read (a rarity) and the data was easy to access. I wrote a bunch of scripts to parse the data and ask questions (this was ~20 years ago). The paper described experiments where the scientists created 6000 yeast clones (yeast has 6000 genes), where each clone contained "a deletion of a single gene" and they showed which genes, when deleted, had fatal effect (IE, the yeast could not grow as a viable organism on yeast medium). The data table was a list of genes that had not been previously known to be "required", and when deleted, would cause the organism to not grow (IE, it died, so you could assume the gene's protein product was required for life). I was asked to make all sorts of tables showing that the genes that got removed belonged to certain classes, or at least had enriched population of certain classes. Since I've always been interested in overlapping genes, I instead spent time scripting some range intersection queries on the data tables (IE, assuming all genes are intervals on a line, find the genes whose intervals intersect). What I found was, for each gene they reported as a novel important functional gene, it intersected an already known important functional gene. So, the most likely conclusion is their table was a bunch of false positives- they deleted gene X, but also truncated gene Y, where Y was already known that if it was truncated, would lead to loss of organismal viability. I wrote a nice letter to the authors explaining what I had found and never heard back (I also dropped that project, explaining to my PI that it was unlikely the data was of high quality). A year or two later, the authors published a new paper explaining how gene overlaps had important functional significance in yeast... If I were rich, I'd fund an institute, but instead of trying to discover new things, I'd find a bunch of data scientists who went around looking for low-quality papers and properly letting the community know (while publishing all work so that people can verify for themselves the quality of the paper).
- mar77i 7y agoThis is a great idea, Be it only to dampen all the published science and research really is with all these reproducibility crises around. There has got to be a market for this kind of honest work, to make the existing world of published data a better place.
- mindfulplay 7y agoIt's appalling that even proper science research can be fraudulent. If only she also focuses on the much shadier and shittier social "sciences" papers that media outlets and normal people seem take at face value.
- allan_golds 7y agoPaywall
- rozab 7y agoHer powers of pattern recognition must be extraordinary. I know that enhanced pattern recognition has been associated with savant syndrome [0]; I wonder if her abilities are worthy of scientific study? Or maybe it just seems incredible to me because I'm particularly bad at this task. Also, she has a Patreon [1] which currently only brings in $40 a month. Just thought I'd bring that to people's attention. [0] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2677591/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2677591/ [1] https://www.patreon.com/elisabethbik https://www.patreon.com/elisabethbik
- Nasrudith 7y agoVigilante is the wrong term on so many levels for her work. For starters it implies illegality, slipshod at best due process, and a proper authority. Elisabeth Bik is essentially being a good citizen - doing exactly what she should as a reader calling out improprieties. I wish her luck in her endeavor and note that she proves what actual journals could do to stay relevant as a service when true distribution costs aren't there - vetting the data and giving a reason to pay for the data already peer reviewed by others.
- bayesian_horse 7y agoA vigilante does not need to do illegal things. The literal meaning from latin is "watch stander".
- tomrod 7y agoCurrent usage implies illegal things done. With due respect to Latin, the choice of vigilante is odd.
- dmos62 7y agoVigilante, in its current mainstream use, means a vigilant person who enacts justice without authority. The justice part is not in the etymology of the word, however. Vigilante, structurally, just means someone who is vigilant. I think calling a watch-dog or an independent peer-reviewer a vigilante is not inappropriate. It's a stylistic choice. I think it's important in literary education to be able to distinguish between what a word is and what cultural baggage it has (how it's used). Of course, where a word ends and its baggage begins is debatable, but it's a good debate to have.
- tomrod 7y agoI think we are aligned on our view of the word choice
- bayesian_horse 7y agoWhat about vigilantes in comic books and derivative media? Clearly positive! (though also illegal)
- Railsify 7y agoI think of this scenarios like she discovered every-time someone uses a line like "studies show", the only thing the study shows is that the author wants a bump in clout.
- symplee 7y agohttps://en.wikipedia.org/wiki/Weasel_word https://en.wikipedia.org/wiki/Weasel_word There's a great list of examples halfway down the page. For example: "A growing body of evidence..." (Where is the raw data for your review?) "People are saying..." (Which people? How do they know?) "It has been claimed that..." (By whom, where, when?) "Critics claim..." (Which critics?) etc...
- nyxxie 7y agoAcademia is almost entirely based on trust and reputation, which we're seeming to discover is not a useful heuristic if your end goal is a net gain in uncovering the truth of the phenomena around us. If you ask me, credibility should be based on reproduction of results rather than reputation of the author, name of the sponsoring institution, journal title, or a vague "peer reviewed" badge. New papers should be by-default untrusted until several reproduction attempts have been successfully executed. This would incentivize authors and scientific institutions to produce science of quantifiable quality.
- ISL 7y agoTotally agreed. Please fund us enough to do replication at that level. (Although, at least in my field, replication is gives less bang for the buck than improved measurements. If I measure a thing, and then you measure it with 10x higher precision, you're not just replicating my result, you're moving the field forward.)
- Retric 7y agoIndividually papers are generally not trusted which is why literature reviews are a thing. https://en.m.wikipedia.org/wiki/Literature_review https://en.m.wikipedia.org/wiki/Literature_review The issue is not on the science side, but how results are communicated to the general public. Administrators tend to add as much hype as possible, and reporters strip out all the important details.
- bayesian_horse 7y agoEvery fraudulent paper adds to the scientific noise rather than to the scientific information. Not only are they wasting their own funding, they are also wasting other people's time and money who often can't afford to ignore prior work. At the very least such papers come up in peer review. And apparently, fraudulent papers can get cited quite a lot in practice!
- i000 7y agoIs this assessment (reviews over papers) based on your own experience? As a scientist I would say quite the opposity is the case, reviews are sloppy in citations, per editorial guidelines have to be written in a positive optimistic tone, and often overstate the claims of the cited articles.
- RcouF1uZ4gsC 7y agoThis is one of the strongest arguments why scientific publications should be open. The more people who have access to the science papers and have the opportunity to find issues, the stronger our scientific foundation will be.
- Enginerrrd 7y agoIf you look at arxiv though, the result has been the proliferation of a ton of really low quality, garbage papers. I wonder if a you could crowdsource the review with voting and discussion a la stack exchange style. That might actually be a good solution, particularly if you have to get vetted as being knowledgeable and constructive in order to vote.
- comicjk 7y agoI use a site called "ArXiv Sanity Preserver" - it's mainly for machine learning papers based on its current audience, but it provides pretty useful filtering based on user reviews. In any case, you can still estimate the quality of a paper with a minute of research into the authors. This is a good idea even if it's in a journal.
- selimthegrim 7y agoI believe there’s a site called scirate
- ac29 7y agoOpen access doesn't necessarily imply free and not peer reviewed like arxiv. There are plenty of good, peer-reviewed journals that are open access - they are certainly not free though ($1-2k when I was publishing several years ago).
- oefrha 7y agoThere are also peer-reviewed “arXiv overlay journals” that are very cheap to run and consequently cheap for authors. For instance, Timothy Gowers (Fields medalist, prominent figure in the movement against big publishers like Elsevier) announced[1] another one of these last week: > I am excited by the business model of the journal, which is that its very small running costs (like Discrete Analysis, it uses the Scholastica platform, which charges $10 per submission, as well as a fixed annual charge of $250, and there are a few other costs such as archiving articles with CLOCKSS and having DOIs)... [1] https://gowers.wordpress.com/2019/10/30/advances-in-combinatorics-fully-launched/ https://gowers.wordpress.com/2019/10/30/advances-in-combinat...
- Trias11 7y agoAI will make her work so much harder soon!
- bayesian_horse 7y agoIf you can create an AI that can fake these images well enough, maybe you should publish that instead of publishing fake research.
- jonsen 7y agoOr it will do the work for her.
- comex 7y agoThat's what I was thinking. Manually reviewing 20,000 papers is simply an astonishing feat. Heck, even searching a single paper for anything that looks like anything else in the same paper (possibly rotated, scaled, or alpha blended) might be beyond me. But it's the kind of task a computer vision algorithm should be able to do very well at. In fact, I Googled it and found (what else) some papers about it, e.g.: https://arxiv.org/abs/1407.6879 https://arxiv.org/abs/1407.6879
- LessDmesg 7y agoAh, so consensus is not a measure of scientific fact. Glad people are catching on to that. Maybe if enough people smarten up, we can dismantle the "97 percent of climate scientists" fairy tale that the climate alarm propaganda is based upon.
- Pinegulf 7y agoShe is brave. Exposing 'pretend science' gets you backlash. Just see consequences from 'Sokal Squared': https://www.chronicle.com/article/Proceedings-Start-Against/245431 https://www.chronicle.com/article/Proceedings-Start-Against/... BTW, If you like what she is doing, you might like RealPeerReview (https://twitter.com/realpeerreview https://twitter.com/realpeerreview)
- n4r9 7y agoDo you think Sokal-type pranks are legitimately exposing pretend science? It seems to me, the strongest conclusion you can make is that some journals are over-eager to publish studies with edgy titles or themes. This might bring into question the average level of scholarship in a field but it doesn't directly challenge whether a field is legitimate. Moreover I don't think a journal with a title like "Gender, Place, and Culture" would classify itself as scientific. Its website certainly doesn't do so [0]. You can't expose pretend science if there's no pretension of science. [0] https://www.tandfonline.com/action/journalInformation?show=aimsScope&journalCode=cgpc20#.VeTSWpjDWRY https://www.tandfonline.com/action/journalInformation?show=a...
- Pinegulf 7y agoNo. It's not to expose pretend science, but pretend science publications/magazines. I believe (No, I don't have evidence) that fields of 'X - studies' have people performing research with rigorous practices. Yet, those holding to standards are marred by nonsense publications from people who disregard standards. Edit: This is enabled by magazines printing without... you know, Review.
- geomark 7y agoIf you have not watched Peter Boghossian and James Lindsay on the Joe Rogan show you should. Very entertaining and shows how ridiculous these publications are. https://www.youtube.com/watch?v=AZZNvT1vaJg https://www.youtube.com/watch?v=AZZNvT1vaJg
- maxiepoo 7y agoIt seems the consequences of 'Sokal Squared' are because the papers contained falsified data, which is very different from what Dr. Bik is doing here.
- Gatsky 7y agoThis kind of thing gets too much hype. I mean, these people are just sloppy, and catching them out is just a matter of how much effort you want to put in. Generally in any field you get to know quite quickly who isn't trustworthy, and largely ignore their papers. If only journal editors had the same information. What is a bigger problem is papers which seem important but actually reveal nothing due to statistical errors, mistakes you can't ever find without getting the data and redoing the analysis, irrelevant or contrived model systems, inadequate controls, inscrutable analytical methods etc
- bayesian_horse 7y agoApparently there are quite a lot of "sloppy" people and they are screwing up even more researchers.
- jononor 7y agoWhat about people who are not 'in the field' (presumably several years of work there), how do they know who to trust and not?
- Gatsky 7y agoDon't get me wrong, ideally every paper would be trustworthy, but working scientists are well aware of the issues, and aren't waiting for a posse of armchair crusaders to save them. If you aren't in the field, then it's difficult, although perhaps inconsequential.
- bjornsing 7y agoLooking at images of crystallized materials and interpreting all similarity between small regions as proof of scientific fraud is a bit dangerous though... If I had to guess I’d say it’s more likely that that electron microscope image in Bik’s embedded tweet is genuine than not. This whole situation is a farce and an embarrassment to science though. The motto should really be “adhere to the rigorous standards of science, or perish”.
- 9nGQluzmnq3M 7y agoTake a look at the full-size image: there's plenty of clear clone tool action going on in there. The red blob is particularly damning. https://twitter.com/MicrobiomDigest/status/1174461680580882432/photo/1 https://twitter.com/MicrobiomDigest/status/11744616805808824...
- ladberg 7y agoSomeone replied to the tweet mentioning exactly that, but she seems pretty sure that it's fraud. I'm closer to believing her because I'd bet the original authors would challenge her if called out incorrectly.