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vikramkr
searching PlanetScale…
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841.
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by
vikramkr
6y ago
Interest rates are at a record low. Amd is at a pe ratio of like 100, the average pe ratio today is around 15 iirc. With a growth expectation increasing because of apples adoption and all, plus with record low interest rates, a 60x multiple
842.
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vikramkr
6y ago
The scientific field is already doing a ton - Neuro is one of the most active areas of research right now. Behind COVID that is, currently pretty much everything is on hold for COVID. Pre-COVID however oncology and neuroscience were already
843.
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vikramkr
6y ago
It's a good example of the importance of using respect/a large platform appropriately. If I was in your position I also don't think I'd have really fact checked it, since that level of scrutiny on everything would be nea
844.
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vikramkr
6y ago
Neither of those could really be counted as "extinguished" though. Hotmail evolved into Outlook, and Xbox is doing quite well. Those seem like pretty solid outcomes.
845.
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vikramkr
6y ago
Are there any good examples of embrace extend extinguish under nadella's tenure? I keep seeing this meme everywhere (including in this thread) but git is doing fine, Linux is doing fine. The only notable things I've seen extinguis
846.
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vikramkr
6y ago
Chitosan is not used as a preservative and isn't an alternative to aluminum.
847.
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vikramkr
6y ago
Even if you've read HP lovecraft, the lessons contained are pretty specific to the 1920s. Air conditioning, non-euclidian geometry, previously unknown colors, cities, black people, poor white people, immigrants, native americans, inter
848.
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vikramkr
6y ago
If the microbes were dead then yes. If they are still alive, presumably they've been doing a basic level of life stuff for the past 100 million years which involves replicating and preserving DNA.
849.
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vikramkr
6y ago
There's an offhand comment about the first remote demo day failing - is that true? And what does a demo day failing mean? Were companies unable to raise money, and if so, is that because of the macroenvironment or the new remote setup?
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YC S20 Virtual Demo Day
(blog.ycombinator.com)
2 points
by
vikramkr
6y ago
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0 comments
851.
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vikramkr
6y ago
I think regular folks are already pretty clued into how other things like text mining and sentiment determination have big markets considering how strong the backlash against tech politically is right now. The everyday public and by extensi
852.
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vikramkr
6y ago
That 20 watts is to run the network. Our brain has had a billion years to work out details of the architecture and encode a lot of basic stuff as instinct (and it still sucks at a lot of things). You should be counting that energy cost as w
853.
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vikramkr
6y ago
From a management perspective a company where software is not the product makes the software team is what's called a cost center. And companies love cutting costs. At a company where software is the product, the software team would be
854.
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vikramkr
6y ago
I agree with one point and disagree with another. The point about taking a lot of time - people would be well served to really internalize that. Even in something like biotech you have a push for development and exists within a year of star
855.
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vikramkr
6y ago
Sayong they are converting water to fuel focuses on the wrong (least important) part of it. The point is that it fixes CO2 from the air into hydrocarbon fuels via generating carbon monoxide and using the Fisher troph process to assemble fue
856.
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vikramkr
6y ago
This is some really cool stuff on a scientific level - RNA binding proteins are just really fascinating and throwing in some post transcriptional splicing and, wow. That's some really fun stuff! One awesome thing about the state of bio
857.
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vikramkr
6y ago
That is super weird. I imagine it wont be long till the seeds are identified, but whatever the story is behind these, its bound to be at least mildly interesting.
858.
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vikramkr
6y ago
Continued gerrymandering keeps the incumbents in power. Ongoing voter suppression targeted at minorities silences their political voices and swings elections, denying democracy its due. Since 1990, the Republican party has won the popular v
859.
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vikramkr
6y ago
You say "even" as if two powerful leaders that helped catalyze enormous changes in society resulting in a fundamental shift in who has power and autonomy would somehow be less likely to have ruthless enemies. Those are the folks w
860.
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vikramkr
6y ago
You see giant protests occupying cities for weeks and your first thought is that americans are totally OK with the state of things? All those folks on the street in Hong kong - they must just be out there celebrating their loss of liberties
861.
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vikramkr
6y ago
People can absolutely do whatever they want to themselves of course. My concern is when they turn around and sell CRISPR kits and misinform the public so people like me (biologists/biohackers with connections to the DIY space) get aske
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vikramkr
6y ago
Now that you mention it, I wonder if maybe these hand sanitizers have methanol contamination because the manufacturer saw that denatured alcohol was cheap/available and tried to swap out their usual source to make a quick buck?
863.
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vikramkr
6y ago
Toxicity for methanol also comes through skin absorption and inhalation of vapors. The effect you're concerned about there is what happens when your body breaks down the molecule - formaldehyde is an intermediate metabolite and is pret
864.
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vikramkr
6y ago
Reading through the number of off target effects and poor controllability of the process in this cow, this just makes the case of the CRISPR baby that much sadder. This is why irresponsible biohackers self injecting with crispr and unethica
865.
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vikramkr
6y ago
Even with the disclaimer that the variables are all probably correlated, I think the author is vastly vastly underestimating how strongly correlated these variables are going to be. Raw mental power and creativity + long-term planning and v
866.
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vikramkr
6y ago
I wonder how that behavior is reconciled with the idealistic basis of YC's application process where its open to everyone without needing warm intros and all. Pretty hypocritical to decide the only people worth your time are the people
867.
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vikramkr
6y ago
I'm unsure about your example of James Watson as a successful scientist. He was successful, yes, and was a scientist. But I don't think he was successful as a scientist. Rosalind Franklin made the key scientific insights crucial t
868.
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vikramkr
6y ago
I hope this leads to drastically lower rents in the NYC area. A lot of companies like mine still need some space, but even needing a little bit means we have to head way out of the city before we can find anything affordable. That makes c
869.
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vikramkr
6y ago
So this didnt come across in the title - but the first company they use as an example is one Amazon actually did invest in? And that was four years before the "competing" product (which is literally just providing data for AI trai
870.
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vikramkr
6y ago
That doesnt jive with the string of spectacular silicon valley blowups recently. Hype seems to be just as good a substitute as product market fit. And it seems that derisking unit economics to show you can be profitable doesnt matter at thi
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