vibrio

9 ms·

121.
by vibrio 3y ago
IMO, “Single cancer cell” isn’t really a the unit. Solid tumors act more like a mini organ with different types of cells having roles: driving blood supply, immune suppression, or enabling and executing metastasis are examples. Cancer isn’
122.
by vibrio 3y ago
“They also tend to over-estimate the effect of peer review (often equating peer review with validity).“ In my experience, scientists ate comfortably cynical about peer review- even those that serve as reviewers and editors- except maybe jun
123.
by vibrio 3y ago
I don’t think that is pedantry. Translations are interpretations by a third party that may or may not have an opinion on the topic.
124.
by vibrio 3y ago
The size of the single virus is a false metric here. There is a wide range of respiratory droplets containing virions. Those droplets can range from visible (way bigger than a mycobacterium ) to only large enough to hold one virion. The siz
125.
by vibrio 3y ago
“Scratching the surface on talc“ Did you pun here on purpose? Almost ironically, Talc is a standard of care for malignant pleural effusions ( mesothelioma, long metastasis is other cancers cause “pockets” in the lung cavity which collect f
126.
by vibrio 3y ago
The scientist Lew Cantley has done nice work in this area. He describes how fructose changes liver metabolism, and is linked to some cancers. His concern is mostly large amounts of high fructose corn syrup, and if I recall, one would have t
127.
by vibrio 3y ago
The hope level can be lowest (and cynicism maximal) late and at then end when one is the senior student and the major (only?) contributor in the lab or key project with no one coming up behind. A weak thesis committee won’t stand up to the
128.
by vibrio 3y ago
I wouldn’t say outfight rejection of intelligent design. If one studies viruses, much time has to be spent considering evolutionary aspects, just due to their numbers, variability, and life cycle. The involvement of an Intelligent Creator a
129.
by vibrio 3y ago
I don’t know. Do hydrogen atoms have a purpose? Do rocks have a purpose? I think of them having properties that maybe can be applied towards a purpose. To me Purpose implies specific intent. I’m not sure where that intent comes from for an
130.
by vibrio 3y ago
This is reasonable. A purpose sounds like a predetermined goal, which isnt how I think about viruses. They could have an effect that leads to a benefit, npbut that to me seems different than purpose. Again maybe me being pedantic, but I’ve
131.
by vibrio 3y ago
Just going by the definition of purpose, which I would take as the reason viruses exist. I think there could have a purpose in their “actions”, such as changing enevelope tropism to broaden target cell range, or more tightly binding a cell
132.
by vibrio 3y ago
Purpose of viruses? At the risk of sounding pedantic or snarky, that sounds like intelligent design. The “purpose” of viruses is to optimize making more viruses. Sloppy viral biology may allow some transfer of genes, and if that helps virus
133.
by vibrio 3y ago
I know many in the US that fluoride treatments that are ridden with fillings. I think you have a tooth shape and oral microbiome, that is resistant to cavities, rather than the fluoride treatments. How can we know what the provided the bene
134.
by vibrio 3y ago
Peter Schultz and team has been working on this problem for more than a decade. His company Ambrx was founded 10 years ago. They've done ok with fundraising, but I'm not sure he raised 'a hell of a lot of money'. Sure th
135.
by vibrio 3y ago
This stuns me for some reason. I was not explicitly aware of this. Why? Just left over momentum from something? Is there a bias in direction (overall or among subsets)?
136.
by vibrio 3y ago
I came here to say I could practically see Elons redlines on her draft - wether real Elon, or the Elon on her mind. Not a criticism. She has a vision to achieve.
137.
by vibrio 3y ago
Elon would like a word with you.
138.
by vibrio 3y ago
…and they can get that much distance on their rockets?
139.
by vibrio 3y ago
I once barely survived a ride with a taxi driver in Tijuana who claimed to have learned to drive playing GTA. Based on his real-world driving it seemed plausible although We did not have to visit a spray’n’pay at any point. I never got to s
140.
by vibrio 3y ago
“ The super high income (radiology) jobs people are alluding to here (500k-1m) are structured as partnerships that don’t offer employer contributions” Am I reading correctly that having no 401k match would be a concern for someone making $5
141.
by vibrio 3y ago
Wow…I have some reading to do to cover the blackwater>>>constellis thing. That escaped me.
142.
by vibrio 3y ago
Fair and thank you I was feeling cynical this afternoon. I’ll agree his Foundation is a win. I was thinking more of companies on the focus (eg. calico) and not of funding organizations like the CF foundation (huge success story) and HHMI (g
143.
by vibrio 3y ago
Anecdotally, Billionaires pushing money into science so they or a loved one can live longer has been some of the most misspent research money. There have been a good number of time I’ve read about a “genius financier” or “high tech magnate”
144.
by vibrio 3y ago
Agreed. For young scientists, asking why the paper didn’t make it into a ‘better’ journal can be a good thought experiment, but dismissing it on the basis of impact factor is against the whole purpose of science.
145.
by vibrio 3y ago
Well put. Regrettably, McKinsey will continue to McKinsey.
146.
by vibrio 3y ago
I was expecting to hear Jello Biafra singing on the other end of that link.
147.
by vibrio 4y ago
We can throw in Vienna also (VY-enna).
148.
by vibrio 4y ago
Correct. Now do Cairo.
149.
by vibrio 4y ago
100%. As someone who has seen a ”normal, orderly” childbirth, I’m not sure it’s not already the most dangerous thing an average woman does.
150.
by vibrio 4y ago
it is here, and as it grows, much of the pain of drug resistance won't be chaos and screaming in the streets. It won't happen all at once. It will increasingly impact people getting routine procedures, or otherwise minor injuries.

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