searine

65 ms·

631.
by searine 11y ago
That is the kind of tasteless shit architecture that only LA could produce.
632.
by searine 11y ago
>DNAnexus, Seven Bridges, and Illumina BaseSpace all provide cloud storage and analysis. "Analysis". There is a difference between meaningful analysis which answers long standing questions of biology, and running a program whic
633.
by searine 11y ago
The bottleneck in genomics hasn't been cost since about 2012. The chokepoint is analysis. Most biologists don't know how to program, and most programmers don't know biological context, neither know statistics well. I work wit
634.
by searine 11y ago
Why pay for features that should be free, and are free with 3rd party tools?
635.
by searine 11y ago
The database isn't expensive, the single-use SNP chips are.
636.
by searine 11y ago
That was the most pretentious review I've ever read. Someone needs to beat this guy over the head with a copy of The Elements of Style, or at the very least confiscate his thesaurus.
637.
by searine 11y ago
Interesting software, horribly written article.
638.
by searine 11y ago
>It's very hard for me to believe combined therapies can beat evolution. Obviously the faster an organism mutates/replicates the harder it is to slow/stop evolution. HIV for example is "worst case scenario" but w
639.
by searine 11y ago
Not necessarily. Current prevalence of resistance to artemisinin is mostly due to what happened shortly after the drugs discovery. That is, wide-spread single-mode-of-action use. This was due to uncontrolled over-the-counter use in South Ea
640.
by searine 11y ago
No. Monsanto created novel genes, based on real ones.
641.
by searine 11y ago
Not likely. Dude to the chemistry of nucleotides, they can degrade in a particular pattern that obscures the ancestral allele. For example the deamination of cytosine to thymine can leave us with an ambiguity in what in our read for the cor
642.
by searine 11y ago
>Robert Markowitz is working on a memoir. Thriller of the century.
643.
by searine 11y ago
It will never, ever, be able to out compete Dirt + Sun.
644.
by searine 11y ago
Wait, you're telling me a perishable luxury product is a tough market?
645.
by searine 11y ago
Probably have better luck writing your own poker-bot.
646.
by searine 11y ago
That draw distance is giving me Superman 64 flashbacks... In all seriousness. Voxel tech is awesome and I can't wait to see some games implement it fully.
647.
by searine 11y ago
A couple general tips : 1. For second-wave bioinformatic analysis, stick to organisms that have a (semi) decent reference sequence. It removes untold among of noise from your eventual analysis. M. tuberculosis, for example is a good candid
648.
by searine 11y ago
>Things I'm thinking of are, (would like to hear from the experts any hints, tips or links): I mean, if you just want to replicate what they did, that's fine, but it kind of misses the point of it all. Science is about finding
649.
by searine 11y ago
>Edit: The downvoters are free to be subjects for future genetic engineering projects themselves. Where do you think food came from in the first place? Do you seriously think strawberries are in any way a product of a natural process?
650.
by searine 11y ago
I've been following this story pretty closing for several months now. So here's the opinion of an actual research scientist. Q. Does the Em drive produce thrust? A. Undetermined. Several tests from multiple independent labs have r
651.
by searine 11y ago
If you are in a rural area of southern china, drink your gin and tonics daily. If you are in a city, particularly a northern city, I wouldn't worry about it.
652.
by searine 11y ago
Travelers aren't at high risk for malaria. They visit cities and areas where malaria isn't usually endemic. Eradication of malaria has been a failure because we can't reach the more remote areas where humans live with it. Bec
653.
by searine 11y ago
OP should make a startup that manufactures "bad decisions" because he is a goldmine. Do yourself a favor and delete this post.
654.
by searine 11y ago
Genomic vapor ware. When will people understand the problem with genomics isn't complexity, it is a lack of raw data. We simply have not collected enough annotation on what every gene does and how it interacts. Without that information
655.
by searine 11y ago
>Anyone I've ever heard say "programming is easy" is without fail a terrible programmer. Development of a worldclass application, is difficult because of the complexity built into a program of large scope. Knowing enough p
656.
by searine 11y ago
>And how does the Right Question appear if not through exploration and manipulation of the data? Questions don't magically come out of a data set. Doing so is called a fishing expedition and usually results in boring, descriptive re
657.
by searine 11y ago
No I've just seen too many people spin their wheels on "analysis" that is not hypothesis driven. You got to start with questions to get answers, and the hard part of science isn't crunching data, it is asking the right q
658.
by searine 11y ago
>Spending the better part of your young adulthood getting a phd in statistics, unless you want to go into academia, just makes you look like a fool. This is why you are a DataWorker, and not a dataScientist. Anyone can push bits around.
659.
by searine 11y ago
Great article.
660.
by searine 11y ago
Moving data around is just grunt work. Real science requires a creative and critical mind, which takes years to mold.

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