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Genomic vapor ware. When will people understand the problem with genomics isn't complexity, it is a lack of raw data. We simply have not collected enough anno
by searine 11y ago
Genomic vapor ware.
When will people understand the problem with genomics isn't complexity, it is a lack of raw data.
We simply have not collected enough annotation on what every gene does and how it interacts. Without that information, you have diddly-squat.
- toufka 11y ago"Garbage in, garbage out", or, "give me enough degrees of freedom and I can fit an elephant". It's a reasonable retort given what's on display here. On the other hand, if you do collect enough data in a particular domain to be able to call some interesting targets, it's straight-forward enough to validate the method. To presume generality (as the scientists probably do not, though as the article and every writeup I've seen here do) is surely foolhardy. As a side note, if the company wishes to pretty much sell to 'big pharma', why then do they publish these touchy-feely tech-crunch articles at all? Their website is designed for all those web-2.0 ideals of retaining customers and click-through and responsiveness, etc. But I doubt Roche cares about any of those things...
- bjwbell 11y agoThe devil is in the details. Look at all the drug trials that work in mice or even monkeys but not humans.
- et2o 11y agoThis isn't 100% wrong, but it's definitely close. To out it vaguely, there is enormous complexity and structure that we can't even model yet.
- gmarx 11y agoit might be fairer to say that before we even get to the complexity problem we have to solve the raw data problem.