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rubidium
searching PlanetScale…
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13 ms
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31.
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by
rubidium
1y ago
They make it seem like a big deal. It’s pretty much how all software used to ship :)
32.
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rubidium
1y ago
You’ve taken a very small slice of the total workflow to develop cas9 crispr edits. Yes some components are “not crazy expensive”, but that’s not therapeutic production levels. And no sequencing. And no bioinformatics. And then zero tissue
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rubidium
1y ago
I thought it supports most file storage sync solutions? I’m using with the free iCloud level storage I believe.
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rubidium
1y ago
Yes. Aldevron and IDT are two companies (owned by danaher) that collaborated to make this happen. They have multiple authors listed in the NEJM article. https://jobs.danaher.com/global/en/search-results?keywords=S.
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by
rubidium
1y ago
More or less, yes. An interesting part of the study was determining what a clinical dose _should_ be. You need enough to edit enough liver cells. But don’t really want to completely overdo it to limit potentially negative side effects. Seem
36.
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by
rubidium
1y ago
It can make “bad edits” eg off target effects. But in this case there were, as far as is known, none. It’s aided that this was a single nucleotide defect. They specifically tested for off target edits in the mouse study and found no harmful
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rubidium
2y ago
Major diseases have been a part of human history throughout. There is no evidence that mega farming is making it worse.
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Ask HN: Year in Bay Area Biotech?
2 points
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rubidium
2y ago
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1 comments
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rubidium
2y ago
Dude, the number of times outright lying has been done and brushed off in a 24 hour news cycle means it’s totally what they are doing.
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rubidium
2y ago
Would you share what setup you use or recommend for this, both NAS and software for phone streaming?
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rubidium
2y ago
You got books from the library to figure it out. Better than google slop these days?
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rubidium
2y ago
Glad to see Ted Gioia’s work here. He writing over the last year has been helpful in getting new understanding for me. His posts on technology are sane and levelheaded without being Luddite.
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rubidium
2y ago
I have the paid version and it’s not connecting
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rubidium
2y ago
Going way back to the start
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rubidium
3y ago
Yes these were my questions too! It’d be even better if it could be administered by a concerned offspring of an aging parent as they’re likely the first to wonder!
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rubidium
3y ago
Um, no they’re trained to get in as fast as possible. Life >> cost of any door.
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rubidium
3y ago
Historical homes are energy efficient. They don’t require any new resources to build, and will typically last much longer if they were built with old growth lumber. Retro fitting is the way. Don’t tear them down for some new crap.
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rubidium
3y ago
It depends on your role. If your just a SW dev on big team delivering some incremental feature its pretty dull. If you’re reporting to a director or above you can try fun stuff and push the envelope more.
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rubidium
3y ago
This is one of the subjects that I upset about. How did it get so bad? How can we fix it? I’ve tried DuckDuckGo but it fails due to spam too. I think the only viable option in the next 5 years in a good LLM with a user (or community crowd-s
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What happened to my search engine?
(honest-broker.com)
4 points
by
rubidium
3y ago
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3 comments
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rubidium
3y ago
UX started with hardware, it was just called human factors. And most of what they came up with then gets forgotten today.
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rubidium
3y ago
Beg your pardon, but I think I would know (PhD in experimental AMO physics). It was one of these: https://www.ipgphotonics.com/en/products/lasers/low-power-cw...
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rubidium
3y ago
Agreed. A 40W 1550nm laser I used in grad school would burn post it notes readily and slowly burn black painted objects. It gave me a little burn once too (Was like touching a hot stove). 1.5W focused to 100 um would be a zinger, but at 4 m
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rubidium
3y ago
My Maverick went up in price after I bought it at MRSP. But that was a market anomaly. There’s usually a drop some but that amount is excessive.
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rubidium
3y ago
QC is just as solid of theoretical footing at fusion. It is mostly a technical/engineering/materials problem with plenty of room for clever physics to make it easier.
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rubidium
3y ago
“We therefore appoint the most possible mechanism to the superconducting vortices. The low-field absorption of microwave power with the assistance of dc magnetic field points to the small superconducting gap, and the relevant metastable exc
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rubidium
3y ago
No. That’s not actually how most orgs break it down. R&D, marketing, sales is “bringing new business” so are profit centers. This means their budget grows with revenue. Manufacturing, QA, IT and service are cost centers so get squeezed
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rubidium
3y ago
I don’t get negative reviews to my knowledge :) Maybe it’s the balance of regular coffee intake for lowering pH but a naturally higher pH?
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rubidium
3y ago
Nothing that severe. I have beer, toast, sandwiches and burgers. I don't do a ton of sweets / soda but I do some (and if I do my teeth definitely get a fuzz that motivates brushing!). My great grandma loved jello “salad”s (eg jell
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by
rubidium
3y ago
Anecdote time: My great grandmother lived to be 102 and never had a cavity. Kept all her teeth to the end. One time, an orderly who thought she was just being senile tried to reach into her mouth to take out her teeth (thinking she had dent
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