rsfern

45 ms·

481.
by rsfern 5y ago
Cool service, thanks! I suppose I should also elaborate, one hangup that I have is that my primary field (materials, specifically alloy design) doesn’t really have a strong preprint culture. So access to fulltext to build something like thi
482.
by rsfern 5y ago
I really like arxiv-sanity. I browse the trending lists and also like to surf the “similar papers” links I wish there was something similar for the general literature, it only indexes like the ML and vision related communities http:/&
483.
by rsfern 5y ago
One hypothesis I have seen around is that is not so much the time since the last shot, but the longer time span between shots that slows for more robust antibody response Seems reasonable, as many of the booster doses for more established v
484.
by rsfern 5y ago
We are lucky we have vaccines at all; it was never a sure thing. Also, IIRC Sinovac’s Coronavirus vaccine is an “old style” inactivated virus vaccine, and the J&J one is an adenovirus vector vaccine. They are not as effective as the mRN
485.
by rsfern 5y ago
From page 1: > Previous infection was ascertained based on SARS-CoV-2 testing from rapid antigen tests or molecular assays (e.g., real-time reverse transcription polymerase chain reaction) performed before mRNA vaccination and ≥14 days b
486.
by rsfern 5y ago
It seems a bit misleading to focus on just this SALT cap aspect when that is part of a broader tax policy change. It’s at least being pitched as a sort of political compromise to get the rest of the build back better plan through. Thoughts?
487.
by rsfern 5y ago
To be fair, GP did use scare quotes to denote “tax cuts”. The specifics of the tax policy matter, to your point, but I do think it’s kind of common to frame this sort of trickle down attitude in terms of cutting specific taxes
488.
by rsfern 5y ago
Frankly I think the fact that there are no current known omicron hospitalizations in the uk this week is what is not relevant. It’s just too soon to make any conclusion about the severity of omicron from this data point. Maybe it will bear
489.
by rsfern 5y ago
Honestly it kind of seems like you just want it to be controversial. You’re post was off topic (as you prefaced) and I just don’t think it’s constructive. Anyway, “they” is a perfectly natural way to refer to a person of unspecified gender.
490.
by rsfern 5y ago
I don’t know, there are only two randomized controlled trials for early treatment discussed in this paper. Neither had statistically significant results, but the review authors speculate that better statistical power would confirm the trend
491.
by rsfern 5y ago
Right, there’s not way to know that without the clinical trials that are required even for small formulation changes, our quantitative understanding of biology is not that good. But there’s plenty of supply chain and manufacturing aspects o
492.
by rsfern 5y ago
Moderna is starting development on an omicron-specific vaccine, as well as testing their other vaccine variants. I wonder if maybe the manufacturing data required for approval could be expedited in these sort of minor vaccine version update
493.
by rsfern 5y ago
Two points i found interesting: - of the three compounds currently in clinical trials, they’re all relatively similar to known drug compounds, but unnumbered by patents (and hopefully more effective) - the grand challenge in drug design inv
494.
AI generated clinical [drug] candidates, so far(science.org)
2 points by rsfern 5y ago|2 comments
495.
by rsfern 5y ago
Yeah, I agree with that. For me it’s still a nice syntax highlighting tool to help me identify and think through those decisions. I use a lot of hedging/weasel words in my first drafts so I find it helpful to have those highlighted for
496.
by rsfern 5y ago
ChkTeX from sibling comment looks really cool! There’s also a set of style linting scripts by Matt Might [0] that I’ve found really helpful in my writing. There’s an emacs minor mode built around them too, writegood-mode [1] 0: https:&#x2F
497.
by rsfern 5y ago
Thanks for the context! The aha link GP shared seems to be the abstract for the poster discussed in this Twitter thread. So not a peer reviewed study, and plenty of red flags in the poster content according to the Twitter thread, including
498.
by rsfern 5y ago
Several universities I have colleagues at have regular testing requirements for all uni community members, on top of vaccine requirements. Maybe it could be a more widespread thing, but I think you make it seem more one sided than it is.
499.
by rsfern 5y ago
Yes! The turbine blades in jet engines are single crystals of typically Ni or Co based alloys that are grown in a mold. It’s more of a directional solidification process though, I don’t think you could grow a NaCl crystal from solution like
500.
by rsfern 5y ago
There’s a lot of interest in superresolution imaging in quantitative microscopy, where this is definitely a huge limitation
501.
by rsfern 5y ago
Shell completion over ssh is one of the really nice benefits of sshconfig. I’m not sure if this is zsh specific though
502.
by rsfern 5y ago
I love section 4 — “things we tried that didn’t work”
503.
by rsfern 5y ago
It’s not about me personally, I’m just saying you could have been more constructive. Edit — thanks for taking the time to reframe your point about the spoiler :)
504.
by rsfern 5y ago
spoiler alert — the article poses a riddle/challenge to find the sample in question, be careful reading the HN discussion if you want to try for yourself
505.
by rsfern 5y ago
I realize they’ve spoiled the challenge, but Kid A was released over 20 years ago. It’s fine to ask for a spoiler alert, but you’re coming off kind of aggressive here IMO
506.
by rsfern 5y ago
Isn’t HN expressly a medium for crowd-sourcing what’s interesting?
507.
by rsfern 5y ago
Pt and Pd are pretty different from proteins in terms of the reactions they’re used to catalyze, but check out https://opencatalystproject.org/
508.
by rsfern 5y ago
I think Weave.jl is a closer match for Rmarkdown. This project seems similar but geared more towards multi-chapter books instead of self-contained reports https://github.com/JunoLab/Weave.jl
509.
by rsfern 5y ago
It’s super interesting for combining scientific models with modern statistical computation in a flexible way Also, randomized algorithms for all kinds of things are very useful in general-purpose computing
510.
by rsfern 5y ago
> push not the best, but the most profitable solutions Don’t you think that cocktails of novel antiviral drugs are a higher profit margin solution then the vaccines that are already available? A remdesivir course costs almost two orders

More ›