Right, there’s not way to know that without the clinical trials that are required even for small formulation changes, our quantitative understanding of biology

Right, there’s not way to know that without the clinical trials that are required even for small formulation changes, our quantitative understanding of biology is not that good. But there’s plenty of supply chain and manufacturing aspects of the approval that seem like wouldn’t need any more stringency than the ongoing monitoring for the currently approved vaccines, from my lay persons perspective anyway