roadnottaken

12 ms·

61.
by roadnottaken 10y ago
From the article: "there’s nothing that could be described as solid clinical data linking the gut microbiome to depression or anxiety in people"
62.
by roadnottaken 10y ago
Um, explain to me how their expertise could be thrown into pharma?
63.
by roadnottaken 11y ago
If researchers would stop voluntarily sending their papers to private, for-profit journals then this wouldn't be an issue.
64.
by roadnottaken 11y ago
This is nice, but you can lose notes if you write in multiple Papier tabs. One has to be careful that they don't have another open Papier tab before they start note-taking.
65.
by roadnottaken 11y ago
No.
66.
by roadnottaken 11y ago
https://en.wikipedia.org/wiki/Christopher_Poole
67.
by roadnottaken 11y ago
>I don't think there are specific guidelines as to when you start calling something a candidate True, that's why I said "at our company". It differs everywhere, as you mention. My only point was that we screen thous
68.
by roadnottaken 11y ago
Fair-enough. I'm not an insulin expert so perhaps I don't appreciate the particular challenges here. But the way it was described on the website didn't make the task sound too impressive. I was also struck by the money invo
69.
by roadnottaken 11y ago
> construct a roadmap I just don't understand what this means here. Cloning a gene and expressing it in e.coli is something that has been routine for decades . Literally. These simple experiments won't provide a roadmap to d
70.
by roadnottaken 11y ago
Don't get me wrong: synthesizing compounds and expressing proteins is not that hard. Those things can be done in a garage. Extensive pharmacological testing in cultured cells and animals is much, much harder. I respect what you&#x27
71.
by roadnottaken 11y ago
I'm a biologist who works in the pharmaceutical industry. I like the idea of open source insulin as much as the next guy. But. I just took a look at their website and it's a complete joke, frankly. It's basically a high-s
72.
by roadnottaken 11y ago
But as forrestthewoods pointed out, if the improvements in the new version are so marginal, then you'd think there would be a booming market for the old version if it was cheaper (generic). So what's stopping the generic manufact
73.
by roadnottaken 11y ago
This is my question, too. Can iOS updates be applied to a locked phone? Seems like it should be a simple yes/no answer (and I thought the answer was 'no') but I can't find any clarity here or elsewhere.
74.
by roadnottaken 11y ago
Can someone explain this to me? The FBI requests a new version of iOS to be installed on a single phone that was involved in the attack. What, exactly, does this mean? If the phone is locked, how will they install new software on it witho
75.
by roadnottaken 11y ago
That's a reasonable description of some common concerns with covalent drugs, but to say that they haven't had much impact in the clinic is misleading. See, for example * Beta lactam antibiotics (e.g. penicillin) * Aspirin * Prilo
76.
by roadnottaken 11y ago
How come error-bars are so unusual in these sorts of libraries? I'm a scientist and NEVER make charts without error-bars on it, but they're rarely included in charting libraries and when they are it feels like an afterthought.
77.
by roadnottaken 11y ago
PhD programs in the sciences (e.g. bio, chem, phys) in the US also come with a salary/stipend that one can live off of.
78.
by roadnottaken 11y ago
From someone who works in the biotech industry, this is utter rubbish. Most good ideas in biopharma are wrong and don't work. You don't get to really test them out in a meaningful way until you get into human clinical trials. I
79.
by roadnottaken 11y ago
Yeah, what's to stop somebody from just lying about their business affiliations?
80.
by roadnottaken 11y ago
How would your suggested replacement prevent unscrupulous business owners from writing fake reviews?
81.
Insider review of Y Combinator bio-pharma startups(pipeline.corante.com)
5 points by roadnottaken 12y ago|1 comments
82.
by roadnottaken 12y ago
To be fair, the HN mobile experience is terrible.
83.
by roadnottaken 12y ago
What a load of crap. The author has no idea how medical research is actually performed. It's very hard and expensive and data-collection/analysis is a tiny, tiny challenge relative to the complexities and costs of developing nov
84.
by roadnottaken 12y ago
Very interesting, thanks
85.
by roadnottaken 12y ago
How does it handle in the snow?
86.
by roadnottaken 12y ago
I had the same experience. Still don't get it.
87.
Blast from the past: reprint request postcards(googlescholar.blogspot.com)
3 points by roadnottaken 12y ago|0 comments
88.
by roadnottaken 12y ago
Yeah, but liquid water is probably required.
89.
by roadnottaken 12y ago
I agree, this sounds like a great future!
90.
by roadnottaken 12y ago
HN doesn't have a mobile-specific interface. It renders fine on a phone/tablet, but you have to do a lot of annoying zooming/scrolling.

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