philipkglass

375 ms·

2851.
by philipkglass 10y ago
I don't know off the top of my head of any drugs that work in humans but have intolerable problems in mice. I do know that some substances are much more toxic to other mammals than to us. For example, acetaminophen is very toxic to cat
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by philipkglass 10y ago
I would guess that you are right simply because most drugs that initially show promise in mice fail during clinical trials in humans. But it's also worth remembering that the trope in fiction of $REALLY_GOOD_THING turning out to be
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by philipkglass 10y ago
This is a nice improvement. It looks like the translation backend for Chrome hasn't been switched yet. https://www.chinadialogue.org.cn/blog/9258-The-debate-over-t... One paragraph translated through the Google Tr
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by philipkglass 10y ago
I'd say say that transport electrification is going to be more directly responsible for reducing oil demand. It's very important to the climate that electric vehicles get charged with low-emissions sources, but the petrostates are
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by philipkglass 10y ago
I think the reasoning is that understaffing means each examiner can't spend as much time looking for prior art, so things might be patented that should have been rejected by a lengthier prior art search.
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by philipkglass 10y ago
many religions will tell you there is really no limit to human desire Yes, and I've heard both environmentalists and economists say that human wants are infinite. The economists say it in a reassuring tone (don't worry, robots c
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by philipkglass 10y ago
I think that his argument works in the limit case. Above a certain square footage the work of keeping a larger dwelling outweighs the benefit of having more space. (I've avoided buying a larger house that I could easily afford because
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by philipkglass 10y ago
I will actually click ads if they show me things that interest me. I'm not a miser or trying to hide my true interests from advertisers. But weirdly I still seem to see more ads relevant to my interests when reading a niche print publi
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by philipkglass 10y ago
I browse most of the time without extensions other than a cookie editor, since I've encountered a number of weird bugs in my company's own product that turned out not to be bugs but weird interactions with browser extensions I was
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by philipkglass 10y ago
I shouldn't have put "it's all in your head" in quotation marks, because I wasn't there in person and I too doubt that a doctor uttered those literal words. There was however an attitude of skepticism/annoyance
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by philipkglass 10y ago
I had a sibling who struggled with CFS for years. Even before this bad study came out the usual reaction from doctors was you're suffering from mental illness/try exercising/you're faking . It sounds almost like this st
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by philipkglass 10y ago
The last two projects mentioned in the article (Literome and better interpretation of medical images) sound like they may be useful. The projects that are described as cell-debugging and cell-reprogramming sound like the sort of hubristic p
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by philipkglass 10y ago
I too am unhappy about clean energy fratricide between renewables and nuclear power. (Though I think that most of the financial pressure on nuclear in the US is actually from shale gas; renewable generation hasn't been able to grow a
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by philipkglass 10y ago
Those are nuclear-sized dollar numbers. I don't know of any solar PV farm that has been built in a single $3 billion phase. Flexible scaling is one of the big advantages of PV projects over other types of electricity generation project
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by philipkglass 10y ago
The investment tax credit for solar works as you describe. Wind instead has a production tax credit where the owners get a tax credit for each megawatt-hour produced over the first 10 years of the project's life. The tax credit has b
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by philipkglass 10y ago
It's not sufficient to just lean heavily on cash. You also need to have a legitimate-looking explanation for where the cash came from if the tax authorities check up on you. Even if you can work anonymously and get paid via anonymously
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by philipkglass 10y ago
The other big thing is that US per-capita steel consumption (including imports and finished products) is significantly down since the 1970s. This says that US steel consumption per capita went from 622 kilograms in 1979 to 451 kilograms in
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by philipkglass 10y ago
Industry average for solar PV is currently about 5 grams of silicon consumed per nameplate watt of module capacity. That includes processing losses (wafer sawing, etching, etc.) I'm going to assume a capacity factor of 20% for solar PV