patall

61 ms·

541.
by patall 9y ago
No, this only says that the about 20000 SNPs (mutations) that they can accurately measure have a limited effect on variance. What the millions of other SNPs do is not known. For example there are estimates for many many thousands of SNPs th
542.
by patall 9y ago
My sister turned out 6'3, my parents would have given a lot to predict that height some years before (as they feared she might end up even taller). Same is probably true for very small people that give their kids growth hormones. And I
543.
by patall 9y ago
Sorry but no, just because something is yours it does not mean you can do with it whatever you want (I understand that this is a totally non-libertarian view). If you find uranium on your plot of land, you also cannot sell it to whoever you
544.
by patall 9y ago
> GWAS have proven to be, at best, of little value. In fact, due to the unfortunate way that many researchers chase p-values, these analyses often result in misdirection. I would certainly challenge that, its just that some people consid
545.
by patall 9y ago
But thats not the point. The question is whether you can make data public that, while it belongs to you, also belongs (partially) to other people (your siblings, parents, unborn children ...) who might not want to have their genetic data pu
546.
by patall 9y ago
From working in that field, I can tell you this is not true. There are lots of women in biology but in computational biology its more like one in three (and often much less). In the algorithmic and tool developmental parts even more so. It
547.
by patall 9y ago
I would not go that far. With every type of olympics these days, you need to have money to fully concentrate on the sport (including many years before you become successful). There may be some sports that require less dedicated support like
548.
by patall 9y ago
Typical Tesla does X article. Its about the future, its going to be the biggest of its kind, not even trying to compare whats already existing. One other (counter) example woule be next-kraftwerke ( https://www.next-kraftwerke.com
549.
by patall 9y ago
It always amazes me what kind of things you grow up with nearby can be a live long dream for other people (Its probably the same for other people with surfing). As kids, it was just one of the many thing we did, that we were invited at scho
550.
by patall 9y ago
Sure, thats why he let some of his products be produced by political prisoners in states like the GDR. Please excuse, my sarcasm but this man was not the good guy, even if he wanted to make everyone believe that.
551.
by patall 9y ago
I do not think that the media is really the problem, its just somehow the topic does not get all the traction it needs to succeed politically. 'Collateral murder' was all over the media but still nothing happened. The NSA affair w
552.
by patall 9y ago
The thing is that those values would have needed to be repatriated at some point anyways (with the added benefits for everyone). So if the repatriation tax would never have been lowered, at some point cooperations would have had to deal wit
553.
by patall 9y ago
While I agree that Trump is not the stable genius he thinks he is, the drone war existed before. We are speaking of a nobel peace prize winner who seemingly did not have either the ability to recognize the hell he helped create or the b----
554.
by patall 9y ago
I totally agree. Lots of people think they are experts (or have understanding) in health care or biology but for this you need to be an expert in health care development which is only partially related. The major difference is that in tech,
555.
by patall 9y ago
While true, this does not mean a forest would be the natural state of the area. Its more likely it would be part of the mammoth steppe if enough megaherbivores would be around. The vast forest only came later when those were all gone.
556.
by patall 9y ago
Can anyone explain how you cope with the 30s shutdown notice? Do you save your network every few iterations to your SSD or is it feasible to save the whole 16 GB from the P100 within the 30s window? I mean, we can freeze a running operating
557.
by patall 9y ago
I cannot say why he is downvoted but there are some mistakes in his comment. First, there would be 47 shareable elements as you have 46 chromosomes plus the mitochondrial genome. And then, any of the 46 chromosomes (besides the Y chromosome
558.
by patall 9y ago
I do not think that carbohydrates all together are the problem. Its just that our capabilities in understanding (poly-) saccharides are 20 to 30 years delayed compared to other important biomolecules like nucleobases or aminoacids while pla
559.
by patall 9y ago
You have probably no idea how wide-spread CRISPR is by now. There are in the order of at least hundred thousand independ research projects going on right now world wide, this one project does not make much a difference technologywise aside
560.
by patall 9y ago
For Germany as well: https://www.agora-energiewende.de/en/topics/-agothem-/Produk... Its very likely because they only use projected production and use.
561.
by patall 9y ago
That's a comment that you get when you only tell half the truth. While the green party was in power until 2005 and was leading force behind the intial phasing out of nuclear power, the conservative liberal government reversed that move
562.
by patall 9y ago
While it may sound easy to change a polymorphism (and even there only for a single base, don't get me started on larger structural variants), do not forget that you have to apply this one single change to 10 ^ 14 cells (or even just 1
563.
by patall 9y ago
I am sorry for that but to be honest your comment suggests that you do not have tiniest idea of how hard medical research is. Not only are the topics you suggest much more complicated than rare diseases (i.e. we do not know the exact molecu
564.
by patall 9y ago
There are many things that can go wrong with a protein. The simplest is misregulation, like a regulatoy motif being disrupted, gene architecture (TAD) being changed, splicing changes (somehow linked to missequence proteins but only via chan
565.
by patall 9y ago
Interesting discussion going on here. One thing I want to add that might serve as a confounding variable of intelligence and genetic disorders is parental age at birth. It has extensively been shown that especially the fathers age is linked
566.
by patall 9y ago
> Most genetic disorders involve a missequenced protein. Most known do, but thats just due to identification bias. We do not even know how many genetic disorders there are. Nor how many people are affected. Nor can we identify most of
567.
by patall 9y ago
It certainly did not ask for me and just switched from startpage to Google. Also auto-installed the update (against my will) after I had voted to wait a few times, though that might have been autoupdate as it was on my work computer (have h
568.
by patall 9y ago
You are missing nothing, its just that modern molecular biology has somewhat changed in what it regards as epigentics. Now, we usually refer to any somewhat lasting changes (a few cell cycles, sometimes just for a cell phase) to DNA as epig
569.
by patall 9y ago
I beg to differ, it is hard to overestimate the importance of CRISPR. There have been gene editors like zink-fingers or TALENs before but CRISPR is in its total capability is a true breakthrough. NGS on the other side is more or less a grad
570.
by patall 9y ago
Very interesting article. Does the fact that silicon carbide chips work at more than 700K mean that we could built 3 dimensional chips with that (as internal heating would be much less of an issue). I do not have insights what really limits

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