new299

82 ms·

691.
by new299 10y ago
Yes, there would be rare edge cases. But they should be rare and well characterized. Unlike the current situation. Practically how the comparison is done depends on the informatics (yes it's unlikely to be implemented as a X~million sy
692.
by new299 10y ago
That and it should really be the false promise of DNA fingerprinting. There are other approaches that would work far better.
693.
by new299 10y ago
It is to be frank crazy that we're talking about anything less that a 99.9% match with today's technology. We have platforms that for less that 1000USD can sequence (read) a complete human genome. Each individual has millions of m
694.
by new299 10y ago
Honestly the technology is also somewhat flawed. There are much better methods that could be used, and would be less prone to flawed procedures. It's just that forensics so highly conservative and unlikely to move to new platforms.
695.
by new299 10y ago
It's infuriating to read about DNA fingerprinting being used such critical cases when DNA sequencing could be used to far more accurately and robustly compare sample and targets identities. Fingerprinting uses common relatively large c
696.
by new299 10y ago
Artworks was also pretty wonderful. This post has reminded me of so many awesome RiscOS applications. There were so many neat little applications. Most things seemed quite solid too. I guess in part because if they crashed the whole system
697.
by new299 10y ago
Oh my goodness yes. So much to love about !Zap. My first ARM assembly programs were written using the Zap disassembler/assembler extension. I also really miss the way it displayed search results, not seen another editor that does it qu
698.
by new299 11y ago
See if you can find a copy of silicon run: http://www.siliconrun.com/sr_lite.shtml
699.
by new299 11y ago
Thanks for the link. I started reading his thesis. While AlphaGo is obviously exciting, it seems like your uncles approach could help us better understand how humans play go which seems hugely valuable. I look forward to exploring his thesi
700.
by new299 11y ago
In the case of JMLR it's not 10USD per-view. It's 10USD per article published. I'm not sure if that was clear from the comment above. Commercial journals generally charge far more than that per-view. JMLR charge nothing per-v
701.
by new299 11y ago
It's off topic but... Personally I'm the guy who ticks "prefer not to say" when a form requests my "ethnic origin" so I don't particularly like that method of measuring diversity.
702.
by new299 11y ago
In my mind Dropbox became a company not worth supporting when Rice joined Dropbox's board ( http://www.drop-dropbox.com/ ). I don't know what their future holds. But personally, with a board member who advocates war
703.
by new299 11y ago
John Gilmore's political views are well known. And the statement was likely chosen because he felt it was inline with his own beliefs: https://en.wikipedia.org/wiki/John_Gilmore_%28activist%29
704.
by new299 11y ago
My apologies for bring this up again, as I'm sure the developers worked hard on this feature, but since Rice joined Dropbox's board ( http://www.drop-dropbox.com/ ) I'd have severe concerns using anything relea
705.
by new299 11y ago
Here's what I did to stop various scammers calling, I talked to them endlessly. They seem to almost never hang up, they'll just keep going and going. So I was bored one day and decided to see how the scam played out: http:/&
706.
by new299 11y ago
I'd like to see a reference on the Oregon school forced to buy Windows licenses for Macs. But could only find references to Microsoft/BSA raids on school with legitimate licensing issues: http://www.salon.com/2001&
707.
by new299 11y ago
I'm sure it's a great communications tool, however since Rice joined Dropbox's board ( http://www.drop-dropbox.com/ ) I'd have severe concerns using anything released by Dropbox. Even if it's open sou
708.
Government to abandon all ideas of trying to ban strong encryption(petition.parliament.uk)
2 points by new299 11y ago|0 comments
709.
by new299 11y ago
Human genomes are very much not random strings, and in any case if calculating the edit distance between two human genomes they are likely largely similar, and if memory serves there are suffix tree/array based algorithms for bounded e
710.
by new299 11y ago
Yes, though there's the added complication of time to answer however. You can turn a Sanger run around relatively quickly (I'd guess hours). High throughput runs sequence many millions of fragments of DNA in parallel very slowly.
711.
by new299 11y ago
About 6 Gigabases per hour, somewhere in that ballpark. Probably something like the equivalent of the human genome project (which took >10 years and 3 billion USD in the 90s) every few days. Error rates are in the region of 1 to 0.1% gen
712.
by new299 11y ago
> Now there's a plethora of technologies that are both faster and more accurate. Sorry to nitpick, but the inherent error rate of high throughput sequencing platforms is still higher than capillary sequencing. This is more than miti
713.
by new299 11y ago
I recently did it, took about 10 minutes online I think. I would guess the services make things easier for you by suggesting a default number of shares, and automatically filling in director information etc. My accountant also would have do
714.
by new299 11y ago
> But it sounds like you're doing much smaller chunks of stuff for multiple clients? I tend to dedicate myself to one client at a time and work more or less full time on one project. Serial monogamy one might call it... I'm not
715.
by new299 11y ago
> Rate - Daily is good, hourly can also work. My current client will pre-authorise overpayment of a few hours a week if I work them. A little income boost if I want it. How do you manage your hours with a day rate? Is a work day 8 hours,
716.
by new299 11y ago
> OTOH you can charge the company for your lunch every day, which means you get that paid for before corporation tax, income tax or anything else... Hmmm. I think my last accountant told me things like lunch every day were not billable t
717.
by new299 11y ago
Specifically I was talking about the situation where your clients are outside the EU and you wouldn't be charging them VAT anyway. If you are working with UK clients I'd imagine it's most likely in your interests to be VAT re
718.
by new299 11y ago
Yep, having set consulting companies a couple of times now having something like Freeagent is invaluable. Getting a good accountant is important as well, after switching once I now use 3wisebears who I'd recommend.
719.
by new299 11y ago
It's probably worth noting that you only need to register for VAT if you're expecting to make > 82KGBP in VATable sales per year. If you're contracting is mostly remote and outside the UK, you don't need to register,
720.
by new299 11y ago
There are open source ssh clients (I wrote one called hterm a while back). So you could compile it yourself. I agree that being able to check signatures would be nice though.

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