michaelbarton

6 ms·

61.
by michaelbarton 2y ago
totally agree - the article seems to imply that you shouldn't be sitting or standing while doing that for at least 4 hours
62.
by michaelbarton 2y ago
If we’re not supposed to sit more than 10 hours a day, and not supposed to stand more than 2 hours then how are we supposed to spend the other 4 hours when we’re not sleeping? I can’t imagine being on a treadmill or exercise bike for than l
63.
by michaelbarton 2y ago
I curious to hear more about your thought. Would it be that they take a suspect’s swab at the scene and then match against a database?
64.
by michaelbarton 2y ago
why not ennnnnnd? https://bugs.ruby-lang.org/issues/5054
65.
by michaelbarton 2y ago
If it’s a particularly wide piece of wood you could try a router planning jig. I think these are used with slabs Otherwise you could try and get access to a CNC or a large industrial belt sander
66.
by michaelbarton 2y ago
I have not used a belt sander! I prefer to start with a planer, then use an orbital sander! Generally work from 60 grit up to 220 depending on the surface. Popping the grain and covering the whole surface in pencil marks in between each! Fo
67.
by michaelbarton 2y ago
I was going to ask something along the same lines. Is the article analogous to saying python is making programmers less familiar with the underlying hardware. Perhaps something’s we don’t want to think about (boilerplate) and other things t
68.
by michaelbarton 2y ago
As an aside, do you know why fish doesn’t support using !! I generally like it a lot but this is one shortcut I miss
69.
by michaelbarton 3y ago
Looks great! Would you have plans to release a jetbrains plugin in future?
70.
by michaelbarton 3y ago
Anecdata, but I and several of my friends have too. It’s a trivial amount of money ($3) but it just really rubbed me up the wrong way and that’s what led to me cancelling.
71.
by michaelbarton 3y ago
Yes! Having done both I like how short the feedback loop is for ceramics, and how much oppourtunity there is for optimisation!
72.
by michaelbarton 3y ago
Glad you brought this up. The CO2 doesn't go away with geoengineering. It's still being pumped into the atmosphere and will dramatically warm the planet in a much shorter time period if the geoengineering stops
73.
by michaelbarton 3y ago
Thanks for sharing your experience! That is similar to what I heard from others too. I wish you the best of luck with building the business!
74.
by michaelbarton 3y ago
I’d also recommend trying ceramics too! It scratches a similar itch
75.
by michaelbarton 3y ago
How do you make a living? I do woodworking at a local workspace. It seems like the margins are pretty tight unless making very high end furniture
76.
by michaelbarton 3y ago
I prefer: thewifipasswordisonthefridgenospaces
77.
by michaelbarton 3y ago
I liked it. Seems like the author has spent a lot of time in self reflection. In particular the section about the cost of being a champion resonated with me. When I was younger I wanted to be the best at everything I did, and there is a hig
78.
by michaelbarton 3y ago
Perhaps I'm misremembering this but IIRC the news at the time the pressure against the door from the inside made it too hard to pull open at get out.
79.
by michaelbarton 3y ago
Glad to read to you’re much better prepared! Agree about the basement apartments, in particular it seems to be the ones with the doors that open inwards that become death traps with flooding
80.
by michaelbarton 3y ago
Great comment and I would add that this has already happened: https://www.technologyreview.com/2022/05/04/1051725/xenotran...
81.
by michaelbarton 4y ago
All good points. A small note though I believe the Queen started paying taxes in exchange for the state’s help rebuilding Windsor caste after the 92 fire. So seems more quid pro quo than something she felt was the right thing to do. https:
82.
by michaelbarton 4y ago
Somewhat related: there was a discussion on NPR about how new builds will likely be much more popular because of rising interest rates. The cause is that there will be a much smaller supply of previously owned homes because owners won’t wan
83.
by michaelbarton 4y ago
if I’m understanding this correctly this is a way for LLMs to call external APIs by showing them special key words that call functions I assume the output of the LLM is monitored by fixie and the result of the function inserted allow the LL
84.
by michaelbarton 4y ago
Good catch
85.
by michaelbarton 4y ago
Unfortunately some bioinformatics tools require multiple passes over the FASTQ. Spades is an example of this.
86.
by michaelbarton 4y ago
Yes exactly. If the most common tools supported zstd then it would make it easier to store zstd FASTQ. At the moment I believe almost none of them do.
87.
by michaelbarton 4y ago
I did play with long mode and it indeed works much better. I omitted it for brevity and to drive faster the main point about gzip. Pretrained dictionaries could also be useful too.
88.
We're wasting money by only supporting gzip for raw DNA files(bioinformaticszen.com)
148 points by michaelbarton 4y ago|165 comments
89.
by michaelbarton 4y ago
While the topic of compressing FASTQ comes up, you might be interested to know that kmer sorting FASTQ files can lead to around an 8% improvement in compression depending on the diversity. I believe this is because it puts similar strings t
90.
by michaelbarton 4y ago
Sounds great! Glad you’re able to bootstrap it. I ask because I’ve looked into this myself. The issue I see with carbon sequestration is how the unit economics add up. Whether the cost of raw materials, labour, facilities, and scaling R&amp

More ›