medymed

8 ms·

61.
by medymed 6y ago
Would recommend ‘A Tour of C++’, also by Stroustrup. It is quite short, largely updated for C++20, and a reasonably speedy intro for people who know other languages.
62.
by medymed 6y ago
Email to self
63.
by medymed 6y ago
Maybe an alternate distribution would be some number n such that there is one paper cited at least n times, at least two papers cited n/2 times, at least 3 cited n/3, up to n=10 or so. Allows for a bit of a tail and still easy to
64.
by medymed 6y ago
The long tail of artists that makes the platform more long-tail money with minimal cost is comparatively safe. Especially given that artists/labels do the grunt work of loading everything to the electronic platform and even for them th
65.
by medymed 6y ago
When I found that interfaces/abstraction was way more critical to understand than recursion or obscure algorithms for most real projects. Half of the battle of starting (or understanding) any project is clarifying the interfaces in whi
66.
by medymed 6y ago
I often wonder metabolic switching between e.g. fat vs carbs as energy sources would be a good way to force cells to perform some acrobatics and die if they have a distribution of mutations that make them metabolically inflexible. Might be
67.
by medymed 6y ago
Also strongly agree with this. Never used to skip a meal, rarely used to exercise. Now most days I only eat dinner and often exercise beforehand. Would not have thought such a metabolic schedule would be realistic. On days when I have to e
68.
by medymed 6y ago
Alternatively, ‘AirBnb revenue kept at 33% of prior level during worldwide pandemic with far-reaching intranational and international travel bans’
69.
by medymed 6y ago
Or the graduating class writes their own oath
70.
by medymed 6y ago
I don’t think you parsed the paper quite accurately. It was just the same virus as the 50s. There was no gain of function. The mention of gain of function regards debated policy issues in 2015 when the paper was published.
71.
by medymed 6y ago
H1N1 in 2009 may fit well with the ‘antigenic shift’ paradigm of influenza, where there is a reassortment of genes from different types of flu (which might both infect the same animal at once) that create a new hybrid to which there is litt
72.
by medymed 6y ago
I’m not a programmer by trade so I exclusively work on smallish projects, not profit driven but rather interest driven. Percent of seriously considered side projects that I actually start: ~10-20%. Percent of projects started that are ‘fini
73.
by medymed 6y ago
While there isn’t too much clamorous mainstream debate about the current strain (SARS-CoV-2), the first SARS escaped the lab several times: “SARS has not re-emerged naturally, but there have been six escapes from virology labs: one each in
74.
The Reemergent 1977 H1N1 Strain and the Gain-of-Function Debate (2015)(mbio.asm.org)
76 points by medymed 6y ago|25 comments
75.
by medymed 6y ago
Intuition can die often, but on the other hand many individual processes within immunology are somewhat well characterized as far as biology goes, and are amazing. The VDJ recombination process for B and T cell development is a stochastic-e
76.
by medymed 6y ago
In a similar (even stranger?) vein, in the 1950s there were cyclops baby sheep related to maternal consumption of wild corn lillies. Many years later this led to discovery of the sonic hedgehog pathway and related targeted inhibitors like v
77.
by medymed 6y ago
In Haskell you can generate an infinite list of all integers starting from 1 with [1..] This is both very succinct but for best use also requires a sufficient understanding of what goes on in the backend, which is true for many features of
78.
by medymed 6y ago
I would say software integration is more like a docking mechanism between spacestation units that were designed in isolation by different countries than like snapping LEGO blocks. At least software pieces are products of human design and fa
79.
by medymed 6y ago
I’ve often been intrigued at the sense of fascination, cultural and technological, directed towards the USSR on HN. I share the fascination. It may stem from an appeal to see engineered works from a system far different than our own both on
80.
by medymed 6y ago
The other leading theory is that major (non emergent) operations and management changes (like starting chemotherapy) will often be postponed until the senior physicians get back.
81.
by medymed 6y ago
Electronic medical record post-click data load time
82.
by medymed 6y ago
It seems like their simulated model makes certain members of a population less ‘active’ and so at less parametric risk of infection/transmission than in a model where everyone is active. This is useful, and/but doesn’t appear to b
83.
by medymed 6y ago
The many facets of carrying capacity population dynamics-- "The vices of mankind are active and able ministers of depopulation. They are the precursors in the great army of destruction, and often finish the dreadful work themselves. Bu
84.
by medymed 6y ago
For me maintaining interest requires a bit of perspective and context to pick routes of action leading to positive feedback loops of curiosity. If steps 2-99 of the route are boring even if executed in an order of my choice, I try to avoid
85.
by medymed 6y ago
You could try to read a github project and look up syntax when you get stuck. But for languages, I just like to suck it up and go through the text version of the basic tutorial extremely fast. Or watch boiled down video tutorials at 2x. Tak
86.
by medymed 6y ago
I also don't think this approach would be helpful, but regarding these points. 1. Photopheresis units already exist but would require some modification for whole blood irradiation rather than wbc only. 2. There are (a limited number of
87.
by medymed 7y ago
This is great! Best wishes for continued development, will follow. From a user perspective, would be nice to have a version that applies pressure around the head like N-95 or FFP-2 straps rather than additional pressure around the ears whic
88.
by medymed 7y ago
On second thought, I do appreciate fever dream interpretations of things as an intellectual challenge and really enjoyed reading the article.
89.
by medymed 7y ago
From a medical perspective this is quite a hand-wavy fever dream interpretation of the immune system and psychology/psychiatry. It’s like saying you should use python instead of rust because it’s syntax more appropriately recapitulates
90.
by medymed 7y ago
Resident physician in NYC, not yet called as backup on the front lines. From comfort of home at this point refreshing my knowledge of ventilator settings. Also in spare moments have been considering similarities and differences between oper

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