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kuhewa
searching PlanetScale…
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49 ms
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691.
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by
kuhewa
5y ago
Peter McCullough's take flies in the face of the weight of subject matter experts and published evidence on the topic. If you like podcast format, perhaps listen to ZDoggMD's dissection of McCullough's interview https:/
692.
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kuhewa
5y ago
No, not unless Pfizer was a typo and you meant Moderna.
693.
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by
kuhewa
5y ago
The increased risk of myocarditis is confined to ModeRNA 2nd dose, not Pfizer or AZ
694.
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kuhewa
5y ago
I take indigenous American literature to mean authored by an indigenous American. Can you suggest more idiosyncratic and important examples? > this "miraculous discovering" is just another cancel latinoamerican culture stunt. i
695.
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by
kuhewa
5y ago
> Because the Spaniards were, by far, the most benign European imperialists. Laughs in Pizzaro
696.
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kuhewa
5y ago
He just released a fifth book. Don't know how it rates. None of his were particularly about the technical side of production though
697.
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kuhewa
5y ago
http://www.janvwhite.org/
698.
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kuhewa
5y ago
Ideal would probably be a mix of resistance training, maximal intensity-metabolic conditioning work (sprints/HIIT/plyometrics), and low intensity steady state cardio (i.e. zone 2, cardio at the pace.you can hold a conversation). E
699.
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by
kuhewa
5y ago
>Arguably, traditional dead-virus vaccines might provide better long-term protection for this reason, but we went all-in on the new tech. That argument sounds good in theory, but we have data we can look at to assess — Sinovac is inactiv
700.
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kuhewa
5y ago
The same reason they surpressed all evidence of widespread wildlife trade in the city in 2019 and lied to the WHO about it?
701.
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kuhewa
5y ago
You can pith the animal prior to boiling it and probably decrease the amount of total noxious stimuli it experiences, no real reason not to
702.
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kuhewa
5y ago
I'm sure the nearest FBI field office would love to show them how it's done if they asked for backup.
703.
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kuhewa
5y ago
There are more main components than that. Sometimes forces like drift are stronger than adaptive selection.
704.
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kuhewa
5y ago
I think the cottagecore aesthetic grew out of representation in anime and Tumblr reposts, along with other less-practical/mundane aesthetics like goblincore. Rather than an actual back-to-the-land movement. With the pandemic it became
705.
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by
kuhewa
5y ago
It's hard to parse that example, because the citation it contains is to a meta-analysis that provides and effect size of aspirin for MI in the PHS in the form of an odds ratio that is much greater magnitude. Digging a bit more, heres t
706.
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by
kuhewa
5y ago
Not enough time has elapsed to say, but it certainly does appear to put immunity back up to original levels, which were against wild-type, even though delta is worst. https://www.nejm.org/doi/full/10.1056/NEJM
707.
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kuhewa
5y ago
So your example of decades being wasted chasing an initial tiny effect size, all the time, was... An example of a failed mechanistic hypothesis that wasn't based on a tiny effect size.
708.
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kuhewa
5y ago
Scientists aren't stupid. No one saw a paper where a predictor explained 1% of the variance in an outcome and based solely on a significant p value decided that was a great road to base an entire career on. The problem, as described by
709.
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by
kuhewa
5y ago
A negative result won't make a career. I don't think there's much danger when requiring negative results going onto a repository of over incentivising negative results. You can't mandate Nature or Cell publishes negative
710.
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kuhewa
5y ago
Nothing is wrong with publishing small effect size results. Setting a P threshold lower or a a higher bar for effect sizes for journal acceptance will just increase the positivity bias and also encourage more dodgy practices. Null results a
711.
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by
kuhewa
5y ago
Even if so, considering the length of incubation and allowing for a decent Ro, there were very very few cases of COVID-19 in the US in Dec-early Jan. If someone claims they had it at the time based on respiratory virus symptoms, the overwhe
712.
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by
kuhewa
5y ago
Pretty sure FDAAA has mandated reporting results for a while now (although some sponsors choose to break the law). Do you have an example of your scenario of an approved drug with many phase 3 trials pre-registered but only one with report
713.
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kuhewa
5y ago
No because you have to preregister all of them.
714.
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by
kuhewa
5y ago
Necessary but not sufficient. Those are issues that can plague all studies, but at least some sources of bias and error can be mitigated against with randomisation and blinding.
715.
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kuhewa
5y ago
What I'm saying is when the largest trial and the one with probably the most leverage in the meta-analysis included turns out to be completely fraudulent, it doesn't bode well for that not being the case for other included trial
716.
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kuhewa
5y ago
My favourite part of this fraud was: > It appeared that the authors had run entire paragraphs from press releases and websites about ivermectin and Covid-19 through a thesaurus to change key words. “Humorously, this led to them changing
717.
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kuhewa
5y ago
Doesn't bode well for the quality of evidence included in the meta-analysis.
718.
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by
kuhewa
5y ago
But we can't produce anywhere near as much beef as we currently do if it is entirely grass-fed and finished. Not without an unfeasible increase in land use footprint. Hence the conversation necessitates a large reduction in livestock p
719.
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kuhewa
5y ago
> Far more damage is being done to human health by industrial wheat, corn, and soy farming, than cattle grazing. But most cattle production (in the US at least) involves converting those crops to cattle with a conversion ratio that is pr
720.
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kuhewa
5y ago
Yes, it is bad for the environment, and comparisons of the best-case grass-fed, regenerative agriculture, ideal conditions vs the worst version of agriculture to produce a plant based don't change that.
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