What I'm saying is when the largest trial and the one with probably the most leverage in the meta-analysis included turns out to be completely fraudulent, it

What I'm saying is when the largest trial and the one with probably the most leverage in the meta-analysis included turns out to be completely fraudulent, it doesn't bode well for that not being the case for other included trials. This one was 'preregistered' after data was collected among other major red flags and shouldn't have passed QC. That is the type of bias/error that can't be accounted for in the analysis itself.