kanzure

36 ms·

331.
by kanzure 11y ago
Well, given our tremendous struggle with rational design of novel protein nanostructures, my point was that we should avoid that difficulty by designing some ligand-binding proteins only once, then assemble those into the larger structures
332.
by kanzure 11y ago
Why would you need an embryo to select a genotype? You don't need to physically embody genomes in embryos just to get iterative selection.... you can do that informatically before you get to the stage of somatic cell nuclear transfer t
333.
by kanzure 11y ago
I want one of their hyper-aggressive rats: http://biorxiv.org/content/early/2014/04/17/004234
334.
by kanzure 11y ago
other thread fell off the frontpage already? https://news.ycombinator.com/item?id=10492824
335.
by kanzure 11y ago
Sounds like you could get the same benefits by installing sshd into each container and using ssh to execute inside of a single container, rather than using docker/compose "commands". This would allow you to keep your `pip ins
336.
by kanzure 11y ago
> build and run that container every time you have a task to run You don't have to rebuild each time, just use docker-compose rm -f and then run again. The old containers will be nuked, built docker images will be kept.
337.
by kanzure 11y ago
> I don't know how many generations of people breeding it would take to get a selected trait - humans are genetically very similar compared to other species; there is not much variation... so I don't have any idea of what the b
338.
by kanzure 11y ago
> If you've ever read a verbatim transcript of an interview or conversation, you'll know that actual speech is anything but clear When I go to conferences and sit in the audience, I type transcripts in real-time. I somewhat agr
339.
by kanzure 11y ago
Yes, but I am often looking at 10 or 20 things at the same time. I don't need to "read later", I need to read all of them now. I'll probably lose like half my trains of thought if I have to wait multiple seconds to switc
340.
by kanzure 11y ago
Using a phone for search is like sucking in information through a straw. Even if you do find something, nobody really wants to setup copy-paste infrastructure between their phone and desktop/laptop. Yes, I know about AirDroid. Loading
341.
by kanzure 11y ago
Some commentary here: http://lists.linuxfoundation.org/pipermail/bitcoin-dev/2015-... and here: http://gnusha.org/bitcoin-wizards/2015-10-14.log cross-post of https://www.reddit.co
342.
by kanzure 11y ago
Correct, but you can still get binding-specific behavior: https://www.youtube.com/watch?v=Ms_ehUVvKKk https://www.youtube.com/watch?v=q_n0Ij3K_Ho https://www.youtube.com/watch?v=Jml8CFBWcDs
343.
by kanzure 11y ago
Tierra was interesting, but these days I would point anyone interested in that direction instead at Avida and BEACON. https://en.wikipedia.org/wiki/Avida http://beacon-center.org/welcome/ In parti
344.
by kanzure 11y ago
Yeah I really enjoyed your 2014 review of large-scale DNA synthesis techniques. I have been funding a project similar to POSAM except instead of DNA hybridization arrays the goal is genome synthesis. Basic summary is use inkjet printheads w
345.
by kanzure 11y ago
Yeah I guess that is pretty crazy. OTOH, there was a study of a virtual machine where someone filled RAM up with random opcodes and running the machine forward in time brought about self-replicating programs because of random self-copying s
346.
by kanzure 11y ago
Ideally we can find a way to engineer proteins that have known shape and conformations and binding, without having to increase our knowledge about protein folding or DNA folding. Maybe certain amino acids fold more heuristically-predictably
347.
by kanzure 11y ago
Nope, I wasn't involved with Nanorex, just the recovery of the files and then "maintaining" the software ever since I learned about the company's imminent death.
348.
by kanzure 11y ago
One of the startups that fizzled out was Nanorex, which is where Nanoengineer was made. Thankfully they were open to releasing the source code and version control repository when they decided to shutdown. The results of that are here: http
349.
by kanzure 11y ago
Here is where IBLT was specified: https://gist.github.com/gavinandresen/e20c3b5a1d4b97f79ac2 More: http://lists.linuxfoundation.org/pipermail/bitcoin-dev/2015-...
350.
by kanzure 11y ago
> I know I'm simply expanding on what you already said, but ... one way or another, you have to go look at a house that you intend to buy. And you don't want the seller there. So you need someone who is trusted by the seller to
351.
by kanzure 11y ago
> All of the software patent trolls are pretty much going to be out of business in the next 12 - 18 months Sounds like an opportunity to me. They might have existing licensing revenue and they are going to be wondering what to do if pate
352.
by kanzure 11y ago
> What if it's such advanced protocol layering and encryption that those alien signals appear to us to be "cosmic noise"? Another interesting way to speculate is the "under our nose" concept, which is the concept
353.
by kanzure 11y ago
> I've read the early mailing list archives for Bitcoin to see if I could understand Saotoshi's intent in creating Bitcoin. Interestingly, he doesn't seem to discuss it much at all. It seems to be all about the tech. http
354.
by kanzure 11y ago
> Isn't there a startup that's already applied for CFTC approval? Well, there's TeraExchange which applied with the CFTC for trading dollar-denominated bitcoin swaps that are written, quoted and settled in US dollars. Rece
355.
by kanzure 11y ago
> I'd love if anyone can point me to community site for DIY Bio / garage materials hacking. https://groups.google.com/group/diybio
356.
by kanzure 11y ago
> Death is incredibly terrifying. I don't understand it and I don't want to, I just want to live. Do not go gentle into that good night, Old age should burn and rage at close of day; Rage, rage against the dying
357.
by kanzure 11y ago
Here are some interesting previous discussions: https://news.ycombinator.com/item?id=9342348 https://news.ycombinator.com/item?id=8708844 and why not: http://observer.com/2015/02/t
358.
by kanzure 11y ago
> So assuming we fixed that, would you buy it (considering esp that GitLab CI exists and you already use GitLab)? Yes but no, we already switched and we're on to other things. We reported the docker cache issues to you guys a looong
359.
by kanzure 11y ago
> is there a situation in which you would buy CircleCI to go alongside it? Well, we were using circleci for a while until the switch to gitlab-ci just recently. Biggest problem was that the circleci runners lose the local docker cache, w
360.
by kanzure 11y ago
> But I do want to run integration tests before that feature branch gets merged upstream. Specifically, the integration tests should run against the version of the source code in the feature branch that the merge request is about. The ta

More ›