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jostmey
searching PlanetScale…
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181.
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by
jostmey
5y ago
This makes me want to buy a VR headset! I spend 1/3 of my life in front of a computer, and this looks fun. But how do you find the keyboard while the headset is on?
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The Hacker News of Immunology
(b-t.cr)
2 points
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jostmey
5y ago
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0 comments
183.
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jostmey
5y ago
Author here: Because T cell receptors (TCRs) that recognize antigens can drive cytotoxic and other T cell responses, autoreactive TCRs that recognize autoantigens can drive the destruction of healthy cells and tissues with those autoantigen
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T cell selection prevents autoimmune disease, has been reconstituted in-silico
(doi.org)
1 points
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jostmey
5y ago
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1 comments
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jostmey
5y ago
Agree with you 100%. This chart is just barely scratching the surface
186.
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jostmey
5y ago
Author here: Because T cell receptors (TCRs) can drive cytotoxic and other T cell responses, autoreactive TCRs that recognize autoantigens can drive the destruction of healthy cells and tissues with those autoantigens. Autoreactive TCRs are
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T cell selection forms immune tolerance and has now been reconstituted in-silico
(rdcu.be)
3 points
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jostmey
5y ago
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1 comments
188.
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jostmey
5y ago
Same for duckduckgo. duckduckgo is blocking images of tank man during the Tiananmen square massacre
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jostmey
5y ago
> “...researchers note both (organs) have extremely high energy demands.”
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jostmey
5y ago
Why didn't you say so! I mean, if your psychologists said so then it must be
191.
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jostmey
5y ago
Try participating in extra-curricular, volunteering and community activities while working a minimum wage job 20+ hours a week and going to school. Have you worked in a restaurant? It is fu##ing exhausting. At least testing tries to achieve
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jostmey
5y ago
The purpose of standardized testing is identify the most worthy candidate. It is meant to be colorblind. Certainly it is not perfect, and wealthy families can help their kids game the system, but it is at least something . If you remove st
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jostmey
5y ago
You nailed it. I find it funny how people believe a simple molecule made from a dozen atoms is somehow the elixir of immortality, as if aging is a simple biological process that we can flip off with a single switch. If we want to take aging
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jostmey
5y ago
Short sci-fi film beautifully illustrating the dangers https://youtu.be/Eo2OQsPDwBI It is also entertaining to watch
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jostmey
5y ago
I dislike pickups in cities because they are too big. Many times I've been stuck behind pickup truck driver trying to squeeze into a parking lot, waiting... I've got nothing against pickup trucks in rural areas where I grew up
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jostmey
5y ago
How is this the lab origin story more plausible than the original hypothesis that sars-cov2 originated from the wet-markets? Both are places where human and exotic animals closely interact, where sars-cov2 could have jumped. Why do you thin
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jostmey
5y ago
These are case stories about why people don't want to take the COVID vaccine. I've read the United States will never reach heard immunity, which is believable to me. I can't wait for the vaccine to become available to kids so
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jostmey
5y ago
Why I agree with your sentiment, GANs always seemed finickily and unreliable. I am willing to indulge new approaches to find something more robust
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jostmey
5y ago
Someday people will spell words phonetically. They will look back at our languages as primitive throwbacks, like hieroglyphics
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jostmey
5y ago
I agree with the three issues they identify driving up costs. But I fear “Medicare for All” won't fix all the issues, which go much deeper. For example, the US has extremely high standards restricting who can practice medicine compared
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jostmey
5y ago
Providing resources to students who need it is definitely important, and it is equally important not to stand in the way of the next Newton, Euler, or Einstein
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jostmey
5y ago
The article doesn't make it clear if (1) this is just a lone admin submitting a bad proposal that is ultimately dead on arrival or (2) this framework is seriously being consideration as policy. I won't hide my feelings that this i
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jostmey
5y ago
HEPA filters cannot remove nanoparticles and ionizing filters ionize the air, and well, ozone is not good for us. So plants are far superior in this regard to air purifiers, which are useless
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Plant based air purifier – cleaning up nanoparticles HEPA filters cannot?
(gobreth.com)
2 points
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jostmey
5y ago
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0 comments
205.
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jostmey
5y ago
I love this article. But the article misses the use of plants to improve air quality! HEPA air filters can't filter out nano-sized pollutants
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jostmey
5y ago
Yes, but many of new therapies, such as mRNA vaccines, were slow to receive approval, and have been sitting on the drawing board for a decade
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jostmey
6y ago
1. Most point mutations won't result in significant changes, but if we are talking about gene therapy, the specific point mutation probably did effect protein folding or function 2. Proteins in each cell are broken down into unfolded f
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jostmey
6y ago
I've learned a lot about gene therapy. The immune system is a major bottleneck to wide spread gene therapy. If you modify the genetic makeup of cells in your body, the immune system will recognize the new antigens being presented by th
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jostmey
6y ago
At least the wealthy still have to take the test. With essays, there is no guarantee that the person wrote it. There are numerous websites for purchasing essays
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Predicting precancer progression from T cell receptor sequences
(doi.org)
2 points
by
jostmey
6y ago
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0 comments
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