gpcr1949

9 ms·

31.
by gpcr1949 4y ago
Yes, I read a bit on this (apparently real after all) business and I saw CO2 is the carbon source. It just confused me the promotional website does not even mention CO2. When they called Solein carbon neutral, I assumed they are talking abo
32.
by gpcr1949 4y ago
I understand it's fake (what is the carbon source? it is stated to be CO_2 neutral) but I guess I don't understand the point or punchline. edit: as pointed out below and elsewhere, the carbon source is CO2, and I misinterpreted th
33.
by gpcr1949 4y ago
It would surprise me if acetylpropionyl will not have similar effects, it is a close analog of diacetyl, and an equally reactive alpha dicarbonyl substance, and for example generates free radicals at a similar rate as diacetyl[0] and at a h
34.
by gpcr1949 4y ago
You can't convert mass to energy like that in this context. A megaton just means a million tons (of TNT in an energy context). You can say: (the energy released when detonating) a megaton of TNT is equivalent to 46.55 g of pure mass to
35.
by gpcr1949 4y ago
i think parent refers to the sabatier process, so the source of carbon is concentrated CO2 externally provided, not from seawater
36.
by gpcr1949 4y ago
Interesting, however the indole ring is very common in biomolecules, and is also present in tryptophan, serotonin, melatonin and others. Most of these will not have fecal odors, I3PA probably won't either. For another stinky indole der
37.
by gpcr1949 4y ago
That's a substance distinct from indole-3-propionic acid, so it is not a form of indole-3-propionic acid.
38.
by gpcr1949 5y ago
In the end the smartphone is quite irrelevant - the detection happens through a color test that should also be visually clear as a purple color. Also, it is a bit impractical because a color test will ruin the drink (hydroxylamine is poison
39.
by gpcr1949 5y ago
This is a pro-drug, the valeroyl indole amide rapidly gets hydrolyzed to LSD in the body. Same thing applies for ALD-52,1P,1B,1cP-LSD. This also means that at some point, these will be made illegal or will fall under blanket "analog&qu
40.
by gpcr1949 5y ago
Besides plant extraction, 5-MeO-DMT is also very easy to synthesize. For example, a commercially available and innocent precursor would be melatonin (which can be converted in one step to 5-MeO-T using KOH and then to 5-MeO-DMT using the us
41.
by gpcr1949 5y ago
> Finally: every kid can draw up novel structures. Then: how do you actually fabricate these (in the case of real novel chemistry and not some building-block stuff). Noone has a clue! I personally have a clue, and the entire field of org
42.
by gpcr1949 5y ago
The fatalities with bromo-dragonfly where due to a mix-up on the distribution end, not only because of the inherent danger of the drugs. In fact, the local distributor (known as Haupt RC) in the bromo-dragonfly 2c-b-fly mix-up incident, die
43.
by gpcr1949 5y ago
Acesulfame K is not sensitive to degradation at coke pH. In addition to acesulfame K coke zero reportedly contains aspartame as well so that was probably the cause of the off-taste.
44.
by gpcr1949 5y ago
Agreed, though of course not every organometallic reagent is alike. It's quite alright to let students try to do a Grignard reaction (the generation of the Grignard reagent being famously finnicky in the hands of beginners and experien
45.
by gpcr1949 5y ago
Many marketed small molecules have fluorine in them, organofluorine compounds are sometimes in fact preferred because they are metabolically more stable than the non fluorinated compound. example of some drugs that have more than 1 billion
46.
by gpcr1949 5y ago
Soda and other beverages are also 98%+ H₂O though. By most standards even beer would count as technical grade H₂O.
47.
by gpcr1949 5y ago
I think >1 μM activity can be ok depending on what kind of target and what kind of IC50 assay is done. Of course, as you know, comparing IC50s is famously something that cannot/should not be done, because they are assay and conditio
48.
by gpcr1949 5y ago
Journal of Natural Products is a great journal when it comes to natural products, for example when you elucidate the structure of a complex novel natural product this is a good journal to publish it in (alternatives being eg organic letters
49.
by gpcr1949 5y ago
the study did not involve testing on humans, and it even did not involve testing on rats (which imo would not have worked anyway), it is cell assays and binding constants only
50.
by gpcr1949 5y ago
The IC50(reported as 24 μg/mL for CBDA against wild type in the live virus assay or 76 μM in more typical units) is far too high to have a relevant effect, you would probably have to use infeasibly large amounts of hemp products (order
51.
by gpcr1949 5y ago
I think I get what you mean but I don't agree on all fronts. 1. that compounds derive from some difficult to handle gas is only a problem for the process chemists. In this case because the TFA-based precursor is available this is not a
52.
by gpcr1949 5y ago
trifluoroacetyl is a pretty stable substituent, as far as the fluorines go. trifluoromethyl as a substituent is a classic "medicinal chemist's favorite" and will not be labile. for example: efavirenz, fluoxetine, celecoxib al
53.
by gpcr1949 5y ago
which is also by far the best DAW that runs natively on Linux (warning: it costs money, though well worth it)
54.
by gpcr1949 5y ago
They are most likely using resolution via the Pope–Peachey Method. There was supporting evidence found in a laboratory in Guadalajara[0]. It is possible to do asymmetric reductive amination using enzymes but this is out of the scope of clan
55.
by gpcr1949 5y ago
> AFAIK the infamous "shake and bake" technique creates racemic meth the shake and bake method uses "sudafed"/pseudoephedrine. therefore, it will produce d meth > This is definitely true for meth, where almost
56.
by gpcr1949 5y ago
To be clear, I'm not arguing vinyl is a superior format, personally I strongly believe a humble (and typical) 16bit 44.1 KHz "consumer cd" type ready for delivery digital file is for 99.9% of listener use cases completely fin
57.
by gpcr1949 5y ago
What is interesting about this to me is that 99.9% of music mastered and produced in 2021 has a digital step somewhere along the chain i.e. whatever perceived technical advantage the physical medium has in terms of sound fidelity is actuall
58.
by gpcr1949 5y ago
have not used kraken, but the convenience i am talking about is that someone who has never used any cryptocurrency and does not hold any, can simply walk in there with cash and have monero a minute later, ready to use. but it is true that f
59.
by gpcr1949 5y ago
They might have cameras, in any case they are in malls so you will be on those cams anyway. Though as someone downthread remarked, thanks to covid it's no problem to be masked.
60.
by gpcr1949 5y ago
This is in Prague, Czech Republic. edit: and re:KYC, there is a money limit above which you need to provide KYC/registration. This limit is 24000 CZK = 1096 USD

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