Journal of Natural Products is a great journal when it comes to natural products, for example when you elucidate the structure of a complex novel natural produc

Journal of Natural Products is a great journal when it comes to natural products, for example when you elucidate the structure of a complex novel natural product this is a good journal to publish it in (alternatives being eg organic letters). I follow natural products chemistry and together with nat prod rep this is one of the journals where I will make sure to not miss any abstract, this is a top of the line journal in it;s niche. However in natural products chemistry there is the tendency to inflate the importance of measured biological activity, often you will see it reported this or that new compound is cytotoxic against some random cancer cell line but when you read the fine print the compounds are weak and/or not selective. Often this later can prove as the justification of a total synthesis attempt or as the starting point for optimization into an actually potent drug (which does not succeed that often).