3 ms·
It would surprise me if acetylpropionyl will not have similar effects, it is a close analog of diacetyl, and an equally reactive alpha dicarbonyl substance, and
by gpcr1949 4y ago
It would surprise me if acetylpropionyl will not have similar effects, it is a close analog of diacetyl, and an equally reactive alpha dicarbonyl substance, and for example generates free radicals at a similar rate as diacetyl[0] and at a higher rate than other flavorings. The only difference with diacetyl is probably that diacetyl's harms are more well-documented.
Speaking of beer brewing: diacetyl is actually generated during the brewing process and, although considered an off-flavor[1], is important for the characteristic aroma of some beers, one famous example is Pilsner Urquell.
[0] https://pubs.acs.org/doi/pdf/10.1021/acs.chemrestox.8b00400 https://pubs.acs.org/doi/pdf/10.1021/acs.chemrestox.8b00400 (figure 5)
[1] https://onlinelibrary.wiley.com/doi/pdf/10.1002/jib.205 https://onlinelibrary.wiley.com/doi/pdf/10.1002/jib.205
- feet 4y agoFrom a harm reduction philosophy point of view it's honestly just best to have no flavoring whatsoever. All flavorings used are from food products which have been approved for oral use and not inhalation. We have no idea what these compounds are doing to the lungs or other tissues when bypassing first pass metabolism. From my perspective it would be the least harmful to stick with just nicotine + PG/glycerol.